Teorías sobre las migraciones

� t/perently to tbo 4�trccte o:r e#eesive _ao&ell

or th:troprotein. _{'rh$ l.Lver W1lts removed} immetUe t ely tmd Ofa,aycd _{for' Vi tmnin '·} QD4 corotena. t\ppro:d.m�tely

100

f.:t1L uampltta of frenhlv voided _{tueoeo wore}

collected

twice _{(\tl1l.V from the}

rer:tJ!'I1n1ng

two

caimalo

on

ana .e>u(\ the _tutim�ltJ were

on

Imrther

blood eentple.a wero taken _{llt u1aughtcr t·n•� the livere were} veJn£:)Ved. A es.ln.l)le ot i'nee�n:s 'WAG also taken

from the rectum.

-

·.:tlppJ.1cu b:-i the �ri tlGh

Ghlol•Ot'l�

.ll oo.

.2

-

Prapsrod tmd euppltad b� the _Ds117

- 91 -

/.6

Hoy,

curot-me

<'onccntrote _{rmd .!'oec:oe} were

n ol.lOfd

fot"

carotene ueing _{the mtt�4} of

Coo_ro

( 159).

_{ou-otone and} v1 tomin _{A wctre} aotlmated in tbo blood pltllll*l

ua1ns

_the

cethoc:) or iC1l1ble

( 108)

_{!30rt1t'1<.,d by} the 1nclueion ot the 80lJODit1cotiol'l filtep f••

reeommcmdcd by �">r>rrlsh, \Vi o and ftughes

( 5,).

The _met.bo<t or

ounup

on4 Hoettor

(4-6)

Blr�<� d1eeueso4 waa _uaod

_for

_{liver eomplee.} 'l'he -whole li<fwo

wore

minced

t.trul 10

gl*&a ardnl,lle-a or _{tho well} n.Uxed orocluc:t _ut�ud tor

Chromlwa ae wee _{dote1'1111lo4} 1n ox14e and the uatns the

m.ot.bo4 deecr-1 bec:l by _{Bami coe t}

( 129)

• All dotor.m1r.JDt1nne were aorried out 1n dupllea, t e. None ot _tho plaemo aamplee contained _{moo�uronble}

Q\Utnt1

t1 ee

ot

c&rotenc

_1'ru1

no

dot1n1 to t"nd e were 1'oun4

1n tha vi t_oRJ.n A contant, _the 11m.&ll

rtuctu&tlon

_being

of

on er�tie

n�ture.

ln the v1

tF•r.Un

content or t.l.e li _Vtt'f:• The throo l.1vf1re dld eontain ::inll t.r.1ount1: o1' _{�..:• t·t.. tenc}

Lut only

of

the li'!Ute

ordor

n o tv·u

'bacn

t'ouna in 11

v<.il' a o 'f

ah�ep

fed

normully on .,> •frt,llr� •.JX' on h!1 .;t t.r.d

conc:dntrutee

( tlnl'\tbl1ehed

reo.llltG) und &a ro�>orted for ..>'-'St'H'tt-t'e4 thi" exr,eriment _{ore thcnm in fl'oblu 6.}

one lt1VW8 t.1vora Ehe

::1/6/1}8

2'\/G/,.8

'2/7/l:.e

G/7/48

1

�8

)2

2G

,1

�2

2.0

2

₃₃

30

29

285.

/_.. • _7''

'

26

2.8

' 1

₃₀

_,,6

_G

t1 AD . tJY e{\ followlnr- o!!oth cf -nieml on

�/7/�J8

1ntr,ke

_{o!" 1+7}

me. ,,er ooy _{or r1 ntcmo to}

cr2o3

J. ·� tio

1n the _{teeu of}

1 5.7 mg/ermt

cr2o3• _!'he 1'�1 tJ.os

- 92 -

w1

th the calcu lnte4 n 0!-)arcnt ct1goet! b111 t1 eo nre m..'lo\1n

in Tnblo ).

dlgentib111 ttoe ot thG 03lll\:l order .,erer obtn1 ncd ':1 tb

othor �hcop _{toil tht:t MY either Rlone nr} oup;.llC!,<mted lfith

1 5

mg. vi tom1n _{A per d&ly.}

Pced ><�aco�e

Jw'7148

., ... p.m.

fj/7/1,8

o . m. r;». m..

G/7/48

Averngc excz•etion 1 5·

7

'

1 1 . 2

9.6

1 3·'

9·9

1 2 . 8

1 1 .

4.

ApParent d1geet1oil1tf

por can tae;o" 4�

tt Calculnt� !'!'om th� 1·ot·��

rhe

...

12. 1

1 3. 6

1 2.9

10. 2

1 2 . 9 1 2 •.

,

,a�

Ap!)t1l"ent <Uceotib111 ty �crcentuge

ot

•

100

•

"i!i!

nutr1Qlnt

wh�ro f • rot1o nutrient to

vvrfJ.,

tea

o ,. rst1o nutrient to

CraO,

oxcreted.

( 1 29 )

t\U will �e thown lntcr, the carotene oxcrcted rnoy not rep1•eeent, a s hae been Oli�ume<l

lwro.

the

t�1fferenee b twet."tl the carotene 1nc;c·t;tO<l t.nC1 thnt

nbsorbod o� destroyed _in the d1gust1vo tr�ct.

for

eh1•orniur.l 'n� CPJ'otono to obt111n .n

int1.1atltion

ot wherl.i the ll� e t l"Jct1on o f: tho cn r-otonc, 11' uny, \Vtte

nlixinn c11: the oxide ·.: 1 t h t !'):: t'cua

1u

_{the uvpa1·} portion of' the _cHrrcntlva tru c ·t , \?.1cl�ly _{<Jlffet•t.nt} l'&.tio� _we�e

obt o1necl.

but corotune chnnge:e in the d1t&�t.1 "lt: t1.·t•c:te ot

noranal

'.l'b� C.!'fect 0� th10UI•oe1l Oll the etllbili ty or oor�t en� wP.e ale� 1nvoattgotod by 1ncubnt1ng &olutione

o� collt 1t..'i•l onrotcnc wt th 'ltnryinn coneentr"Dt1ones of thiou _r'l cil .for from 14. _to

1 2

houro o t

'7°1.

ln no _car.e

wuo tho e:n�oten� deoompot:\1 tlon eraator thnn in the

controls inC'\.Ib8ta4 t.JnCIOl' _{tll<J GUme} com11t1ono l.mt

wi thout thioure.o11.

From _{thcoe o.xperirnentu it}

oeomo

unlikely that

thiour�'c11 decreueoa the otnb.tl1 ty nf oerotcme _{1n tbo}

di��eGtivc troct.

pla _{aJJn or 11 vur} vitAMin _{� du�} t,, _{v�r1· tlon� 1n the}

converuion _or carotene would _{b o} countet-bAltmaed bV the & tl!Jf) l'Cnlt dftcact o£ the t.1.rro id _{etf)te on v1} tsmin _A J'fHiU iPeliltmta bO thot

only po�\1t1ve

Z"<!!IU!te _{'t70nlu ho.vct} �.ny ret-.sl :a1gn1f1cancc. The Uf1mo u p�.�11en to the ft�llur.e to

o<!tL'<.:.t c�1't�·tcno 1n

the _{:'lln emu or to fJn-y exttmt} 1n _the 11V ut'L• 1.. tH•otc:mc.: in tlto Ll.OCC. or the hZ{OY;>thyr01(1 animal

:for

e:Kf;r:tvl� �.cmld h£)vo 1nd1 et:tted "n net ion d1rectlv _on

the �ru.�yr.te ��tJteM _1nvclvod 1n _tho c:"onverelon, _{,.rld vrh..tle}

D negH tive r·ct:.ult could be explrt 1ned by ruummlng no

.r·CltJtil'HWhi� _{of thi} � t�/.)t'! bettteen thyro1a fUnction r.nd co rotene eonvernion, 1 t oould tt l Go x-esult t"ron o

t:eoreoa«td convct,t..im"' t! U �oc1mtod

w:lth

decreAsed

o lJcorvtion _{o� cu.rot�ne.}

of nnit>�; 1

2 NHH'

to

1 1

timer ru-r ,(.c 1 (!•,t•inrc tht: co,,roe

of _the th:n'orn•otein tre:1tm.t.nt _{f'oll •,\•:1m; by itc deoth} !'or ahcep, ont! Jrt•tJ:.! of thia ;'"l<!ll" 10:1 lb.l. '!tvc w�1Sht 10 <.-one1d­ ortet1 su!'f'lclant to .n·<>llucc:t thyroi d hyncrtt•ophy

( 1 �1 )

tin a t:Uil'lttl

)

rttot�i veu ovor

3

t:imes ��.tc moount ot•

thionracil i'OP _{tht:J loot}

7

_{<"f.lye. It Ct1n} be �onclu4e4 therefore thnt the coro t cmt- metDiml1tHB of _{oheep 1n} a

- 9� -

detcct:ib4f r1-o!f\ tl1e nor-molJ 1� the conversion or edroteno tc vi tt m1.n _{A is} 1nf'1.u �ce� b:t th�

th:,rt·o1d

otn tc·, the \3ff'eot

<'oco

not npc)c·tr to be on the

t:mv;v!l'lo eyet<t�t involved Ol1 on the etab111

t1

o� the

I t 1 o qui to poastbl<t hov.•over

thnt the

tH..;fiot·pt1on ot.' cnrotenG _{rnuy be uffeotecl G1nee}

Althauacn �nC1 t tocJtholm

( 1 61.-)

hDve ol'wl'in thllt

/ )

;:•ue�orotion proaoueea aro roto.rde4 1n the

eypotbfroid

state.

It

YiSlB iutenc'C!o to

re�oo't th1B

v:o1.,k UD1ng

on o h1phc:r carotene int�.lke

( about

2

grlo\DlO

per c'�S 1'.rom o,..

etm·o)

t n t1 t>O�tibly ':.r h1��H!:r thlourttoil

IJ eimi le r cy pe, ·

.

�bt

te

'"�"t! tH.iOd ln thls 1n��Gtigat1on ( on ,J body w :1t:.rllt b::&i� t.hie 1&

ubo11t t'1 ve tlroee

tho

leval used for

tho ohet:p� }

'l'ho rcwu l tc- �ere thft � nno n e tlaose obtu1n� 1n thie 1nvc&Jt-

1got1on. t:o carotene _{t;�: c u�toated in tho}

pla

_on4

vt _{tJ:4rre1n levell! 1n the�e 9na c 1m11er uni�alo}

treate<l

with ,,�ca1ecated th.vr:>l t1 v1ere normal..

Ooodwin _aoncludea

f'rom h1n i'inuingc that the n•1mery t.Hltion o:r

thtourtHtl.l

In _{view ot}

1'0T"O I't'c>�r>tl :· _{� 1lff1 1 1: 1 t: C • n :}

. .

_{)!:C'Ob�Ol1}

{ 1(.1)

i'ed

iot·tm•ted

c� ne!n to c"' lvct.: ot ·i lev�l ot

1 . 5 ems/

100

1t:>P, t-·'\cly v; i r'\t t J t

fo,tn�.!

lt ttl<! or no ci'1"cct on

-

95

.

l.&vol

of C:'.lrotent! 1ntn"e the incrett sod

Jttetfibol.te

r11ltO

on

tho

In document Integración de inmigrantes latinoamericanos en Canadá : políticas sociales y problemáticas de inserción de los inmigrantes (página 65-72)