20.201 Drug Metabolism Problem Set 1 Answer Key

20.201 Drug Metabolism Problem Set 1 Answer Key

O Hydrolysis O O

1.

O OH H

O O

2.

NH₂ NH₂

O

O O

3.

NH₂

NH₂ GS

NH₂ NH₂

N N NH₂ H₂N

4.

NH₂ + NH₂

S S

O O

H₂N H₂N

H + HN

Oxidation O

N O

5.

H + N

H H

O O

Oxidation OH

6.

H H

O O

Oxidation N N OH + O

7.

H H

O OH O

Oxidation

O N N

8.

HO O

N

OH H O

N H₂N O

H

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20.201 Mechanisms of Drug Actions

Fall 2013

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