[PDF] Top 20 Aplicación de flavoenzimas en síntesis orgánica
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Cyclodextrin and Polyethylenimine Functionalized Mesoporous Silica Nanoparticles for Delivery of siRNA Cancer Therapeutics
... surge of particles that passed through tumor blood vessels in the first 10 minutes following administra- tion. The number of particles leveled off after 20 minutes, and approximately 40,000 CP-MSNP/siRNA particles ... See full document
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Targeted delivery of anti-miR-155 by functionalized mesoporous silica nanoparticles for colorectal cancer therapy
... blot analysis showed that NF- κ B (P65) proteins were also upregulated in CRC tissues and CRC cell lines (Figure 1B, C, and F), and Spearman’s correlation coefficient test showed that NF- κ B (P65) proteins were ... See full document
5
Highly effective antiangiogenesis via magnetic mesoporous silica-based siRNA vehicle targeting the VEGF gene for orthotopic ovarian cancer therapy
... magnetic mesoporous silica nanoparticle (M-MSN)-based, polyethylenimine (PEI)-capped, polyethylene glycol (PEG)-grafted, fusogenic peptide (KALA)-functionalized siRNA delivery ... See full document
8
Original Article Hyaluronic modified and amine-functionalized silica nanoparticles as intracellular siRNA delivery carriers in lung cancer gene therapy
... nM siRNA-HA conjugate. Bran- ched polyethylenimine (PEI) with an average molecular weight of 25,000 was used as a pos- itive control because it has been reported to be the gold standard in gene ... See full document
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Preparation and Application of Cell Membrane-Camouflaged Nanoparticles for Cancer Therapy
... of nanoparticles can be easily engineered by coating particles with membrane derived from cells or bio-vesicles of different types ...core-shell nanoparticles for cancer therapy (Table 1) [41-47], ... See full document
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Functionalized self assembled monolayers on mesoporous silica nanoparticles with high surface coverage
... Molecular self-assembly of organosilanes has been proven to be a powerful method to rationally engineer the ceramic oxide surface properties [26-29]. In this process, the organo-silanes are hydrolyzed to create the ... See full document
13
Hollow mesoporous silica nanoparticles for intracellular delivery of fluorescent dye
... Hollow mesoporous silica spheres were prepared by a sol-gel/emulsion (oil-in-water/ethanol) method wherein hydrated silica gel was formed on the surface of ...a mesoporous structure, with a ... See full document
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Novel functionalized nanoparticles for tumor-targeting co-delivery of doxorubicin and siRNA to enhance cancer therapy
... To evaluate the in vitro release behavior of RGDfC-SeNPs@ DOX/siRNA, we investigated the release profiles in two kinds of buffer solutions (pH 5.4 or 7.4) at 37 ° C using the dialysis method. The two different pH ... See full document
6
Mesoporous silica nanoparticles as a compound delivery system in zebrafish embryos
... We have tested the toxicity and the capacity for controlled drug delivery of MSNPs injected into living zebrafish embryos. We find that there is no significant difference between the toxicity of MSNP injections ... See full document
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Targeting Somatostatin Receptors By Functionalized Mesoporous Silica Nanoparticles - Are We Striking Home?
... nanosystems functionalized with this octapeptide for SSTR ...nanocarriers functionalized with octreotide or its close derivatives (Table 1) – and just one out of the published ... See full document
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A GREEN APPROACH FOR THE SYNTHESIS OF DRUG DELIVERY SYSTEM, MESOPOROUS SILICA GRAFTED ACRYLAMIDE –β CYCLODEXTRIN COMPOSITE, FOR THE CONTROLLED RELEASE OF CURCUMIN
... of cancer affect human. According to WHO, cancer is the second leading cause of death ...of cancer patients in south Asian countries are relatively low, this may due to the more consumption of ... See full document
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Cisplatin-functionalized silica nanoparticles for cancer chemotherapy
... the silica samples and the 5 μg/mL cis- platin sample are significantly different ( p≤ ...the silica–cisplat- in system, it is important to note, however, that no apparent synergistic effects were observed ... See full document
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Supramolecular Nanomachines as Stimuli-Responsive Gatekeepers on Mesoporous Silica Nanoparticles for Antibiotic and Cancer Drug Delivery
... the delivery performance, and it showed little premature release at pH 7 and rapid release at pH 6 and ...the delivery system and it was fully functional under culture media ... See full document
145
Effect of Paclitaxel Mesoporous Silica Nanoparticles with a Core Shell Structure on the Human Lung Cancer Cell Line A549
... lung cancer involves oral or intravenous administration of antifungal drug formulations ...Pulmonary delivery is an inter- esting choice because it delivers anticancer drugs directly to the cancerous tissue ... See full document
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Synthesis, Characterization and Antitumor Activity of Fe2O3-Cu2O-TiO2 Nanocomposite on MCF-7 Human Breast Cancer Cells
... 4. Youlden, D. R., Cramb, S. M., Dunn, N. A., Muller, J. M., Pyke, C. M., & Baade, P. D. The descriptive epidemiology of female breast cancer: an international comparison of screening, incidence, survival and ... See full document
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<p>Aptamer Hybrid Nanocomplexes as Targeting Components for Antibiotic/Gene Delivery Systems and Diagnostics: A Review</p>
... nanotubes functionalized with piperazine-PEI and an apta- mer for siRNA transference into breast cancer cells proved that gene delivery could be used to diagnose cancer cell ...for ... See full document
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EpCAM aptamer-functionalized polydopamine-coated mesoporous silica nanoparticles loaded with DM1 for targeted therapy in colorectal cancer
... drug delivery has aroused much interest in recent ...inorganic delivery vehicles, as well as increased knowledge regarding physiological factors affecting drug delivery systems, have opened new ... See full document
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Stimuli-responsive hybrid nanocarriers developed by controllable integration of hyperbranched PEI with mesoporous silica nanoparticles for sustained intracellular siRNA delivery
... of siRNA, as well as enhanced intracellular uptake and endo- somal escape of siRNA-loaded ...functional siRNA was revealed intracellularly by tracking the co-localization of the nanocarriers and the ... See full document
6
Applications of mesoporous silica materials in food – a review
... from mesoporous silica materials was reported by Bernardos et ...(2008). Mesoporous silica- based materials contain pH- and anion-controlled nano-supramolecular gate-like ensembles built up by ... See full document
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<p>Improving Solubility and Bioavailability of Breviscapine with Mesoporous Silica Nanoparticles Prepared Using Ultrasound-Assisted Solution-Enhanced Dispersion by Supercritical Fluids Method</p>
... The product exhibited improved characteristics, such as larger surface, smaller particle size, higher DL, less sol- vent residues and better stability, as compared to the BRE-MSNs prepared by the SIV method. The ... See full document
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