[PDF] Top 20 El ministerio público en el proceso de colaboración eficaz
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Tumor-recruited M2 macrophages promote gastric and breast cancer metastasis via M2 macrophage-secreted CHI3L1 protein
... the cancer cells was normalized to that of the untreated ...of CHI3L1-IL-13R α 2 interaction on c-Fos and c-Jun protein expression in the nuclei of cancer ...cells. Gastric and ... See full document
19
Original Article Roles of tumor microenvironment of metastasis and secreted protein acidic and rich in cysteine in human gastric cancer hematogenous metastasis
... a tumor cell is a crucial step in hematogenous ...of macrophages in tumor cell migration and intravasation involves a loop in which tu- mor cells produce colony-stimulating factor-1 (CSF-1) ... See full document
52
<p>CTHRC1 in Ovarian Cancer Promotes M2-Like Polarization of Tumor-Associated Macrophages via Regulation of the STAT6 Signaling Pathway</p>
... and M2- like macrophages — with opposite ...as M2-like macro- phages, which generally promote tumor growth and ...that macrophages can be recruited to the carcinoma tissue ... See full document
7
<p>G protein-coupled receptor kinase 2 regulating β2-adrenergic receptor signaling in M2-polarized macrophages contributes to hepatocellular carcinoma progression</p>
... of cancer cells by secreting various cytokines, which serve as tumor promoters through their support in neovascularization, immunosuppression and invasion in ...of macrophages treated with GRK2 siRNA ... See full document
6
Human breast cancer cells educate macrophages toward the M2 activation status
... a macrophage population recruited and edu- cated by tumor cells, which are therefore exposed to IL- 10, TGF-β, M-CSF (monocyte colony stimulating factor) [6] and other immunosuppressive stimuli [7], ... See full document
127
IL-10 secreted by M2 macrophage promoted tumorigenesis through interaction with JAK2 in glioma
... THP-1, human monocyte from peripheral blood, was commercially available from American Type Culture Collection (Rockville, MD, USA) (TIB-202). THP-1 was cultured according to the manufacturer’s protocol in RPMI-1640 ... See full document
185
MSC-secreted TGF-β regulates lipopolysaccharide-stimulated macrophage M2-like polarization via the Akt/FoxO1 pathway
... in protein levels was consistent with the observed mRNA variation ...iNOS/ARG1 protein lead to measurable dif- ferences in reactive nitrogen species production; the Griess assay results showed that compared ... See full document
17
Exosomal transfer of tumor-associated macrophage-derived miR-21 confers cisplatin resistance in gastric cancer cells
... The gastric cancer cell line MFC,MGC-803 were pur- chased from the Chinese Academy of Sciences Cell Bank of Type Culture ...rived macrophages (BMDM) were isolated and activated as previously ... See full document
12
The evolving relationship of wound healing and tumor stroma
... new tumor vasculature is leaky, which can allow hematogenous metastases to distant ...are recruited to the tumor stroma and release ...tissue. Cancer cells cause the TME to have a low pH and ... See full document
103
M2 macrophages promote myofibroblast differentiation of LR-MSCs and are associated with pulmonary fibrogenesis
... Proteins were purified from either LR-MSCs or lung tissues. Western blotting analyses of cellular lysates were performed as previously described [39]. Cytosolic and nuclear extracts were prepared with nuclear and ... See full document
60
Macrophages are crucial for epithelial cell death and adipocyte repopulation during mammary gland involution
... on macrophages, as demonstrated by their requirement during the expansion phases of puberty and ...of macrophages with M2 characteristics. Macrophage levels peak after the initial wave of ... See full document
15
Macrophages inhibit human osteosarcoma cell growth after activation with the bacterial cell wall derivative liposomal muramyl tripeptide in combination with interferon-γ
... stimulated M2-like macrophages can inhibit growth of osteosarcoma cells in an antibody-dependent manner Both M1-like and M2-like macrophages have been detected in osteosarcoma lesions ... See full document
174
Human mesenchymal stromal cell-secreted lactate induces M2- macrophage differentiation by metabolic reprogramming
... moves across the plasma membrane, while in the latter, it triggers a yet uncharacterized intracellular pathway. It will be interesting to study the pathway by which UC- MSC-secreted lactate induces these ... See full document
94
Similarity between Some Biological Systems, Organotropism and Metastatic Process: Active Role Played By Secondary Organ?
... of metastasis, but are not considered neoplastic ...non-neoplastic macrophages in the in lamed tumor microenvironment (similar in gene expression, morphology, and ...from macrophages or other ... See full document
9
Cisplatin resistant lung cancer cells promoted M2 polarization of tumor-associated macrophages via the Src/CD155/MIF functional pathway
... lung cancer patients often develop resistance against treatment and disease progression ...the tumor microenvir- onment (TME) has emerged and received much ...fact, tumor promoting inflammation ... See full document
10
Original Article Effect of tumor-associated macrophages on gastric cancer stem cell in omental milky spots and lymph node micrometastasis
... Human gastric adeno- carcinoma SGC-7901 cells were obtained from the central laboratory of the first Affiliated Hospital, Dalian Medical University (Dalian, ... See full document
111
Noninvasive Imaging of CD206-Positive M2 Macrophages as an Early Biomarker for Post-Chemotherapy Tumor Relapse and Lymph Node Metastasis
... in tumor-infiltrated M2 ...of M2 macrophages by targeting CD206 could predict tumor relapse post-CTX treatment in an earlier manner (day 7 or 8 ...in tumor size. The dynamic ... See full document
61
<p>MiR-326: Promising Biomarker for Cancer</p>
... can promote cancer cell growth and intensify chemotherapy ...enhance tumor cell prolif- eration and invasion by controlling endothelial cells and peri- cytes in ...mitogen-activated protein ... See full document
57
Clinical significance of macrophage phenotypes in cardiovascular disease
... Mhem macrophage [38] (also known M(Hb) [39] or HA-Mac ...Mhem macrophages arise from culturing monocytes with the haemoglobin/ haptoglobin complex ...murine macrophages (includ- ing M1 or M2) ... See full document
22
Interferon-γ and celecoxib inhibit lung-tumor growth through modulating M2/M1 macrophage ratio in the tumor microenvironment
... kill macrophages (Figure ...reduced tumor weight by 17% com- pared to the control group ...reduced tumor weight by 27% compared to the control group ...reduced tumor weight by 23% compared to ... See full document
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