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TRPM2 channels are not required for acute airway inflammation in OVA-induced severe allergic asthma in mice
... of asthma is the IgE antibody, which is produced by sensitized allergen-specific B cells ...that TRPM2 channels have no direct effect on allergen-induced pro- duction of IgE (Figure ... See full document
9
Allergen specific Th1 cells fail to counterbalance Th2 cell–induced airway hyperreactivity but cause severe airway inflammation
... Allergic asthma, which is present in as many as 10% of individuals in industrialized nations, is charac- terized by chronic airway inflammation and hyperreactivity induced by ... See full document
8
Loki zupa (Luooukezupa) decoction reduced airway inflammation in an OVA-induced asthma mouse model
... of allergic asthma, which have been implicated in eosinophilic inflammation as well as AHR [5, 23, ...the mice with Loki zupa decoc- tion could be attributed to a reduction in IL-4 ...the ... See full document
17
The adipocyte fatty acid–binding protein aP2 is required in allergic airway inflammation
... in allergic inflammation. We examined aP2-deficient mice in a model of allergic airway inflammation and found that infiltration of leukocytes, especially eosinophils, into the ... See full document
69
Inhibitory effect of Dolichos biflorus extract on allergic airway inflammation and hyperresponsiveness in animal model of ovalbumin-induced asthma
... airways, OVA challenge has induced eosinophil, neutrophil, monocyte and lymphocyte infiltration and activation is similar to that of reported in human ...inhibited OVA induced hyper reactivity ... See full document
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Animal models of chronic experimental asthma — strategies for the identification of new therapeutic targets
... experimental asthma have elucidated the central role of TH2 cells and their typical cytokines in the acute inflammatory process resulting in the formation of ...to airway remodelling and ... See full document
26
Attenuation of allergic airway inflammation and hyperresponsiveness in a murine model of asthma by silver nanoparticles
... and OVA-challenged ...saline-inhaled mice administered saline (sAL), OVA-inhaled mice administered saline (OVA), saline- inhaled mice administered 40 mg/kg of silver NPs (Ag 40), ... See full document
19
Endotoxin Is Not Essential for the Development of Cockroach Induced Allergic Airway Inflammation
... (C3H/HeN) mice were pur- chased from Jackson Laboratories (Seoul, Korea). All mice were housed under specific pathogen free conditions, the American Association for the Accreditation of Laboratory Animal ... See full document
16
Deguelin Attenuates Allergic Airway Inflammation via Inhibition of NF-κb Pathway in Mice
... in allergic airway inflammation both in human and in animal models ...of inflammation [40]. In addition, TNF-α stimulation of airway epithelial cells triggers NF-κB-dependent gene ... See full document
28
Comparable Function of γ-Tocopherols in Asthma Remission by Affecting Eotaxin and IL-4
... of airway lumen in the four model sub- groups ...the airway lumen of the asthma subgroup was found with evident incras- sation and blood vessels infiltrated a large major- ity of inflammatory cells, ... See full document
21
TNF is required for TLR ligand–mediated but not protease mediated allergic airway inflammation
... eosinophilic inflammation in the LPS-mediated model of ...is required in the asthma model by generating recip- rocal bone marrow chimeric mice using WT and TNFR1/2-DKO ...recipient mice ... See full document
88
Inhalation of hydrogen gas attenuates airway inflammation and oxidative stress in allergic asthmatic mice
... Chronic airway inflammation mediated by Th2- oriented cytokines was the most important characteristic in allergic ...of inflammation might provide a benefit for the protection of ...pathologic ... See full document
14
Prevention of allergic airway hyperresponsiveness and remodeling in mice by Astragaliradix Antiasthmatic decoction
... AAD, comprising 9 traditional Chinese herbs, Astragali radix, the drided roots of Astragalus membranaceus (Fisch.) Bge. Huangqi, 15 g; Codonopsis radix, the dried roots of Codonopsis pilosula (Franch.) Nannf., Dangshen, ... See full document
58
Peripheral blood eosinophils: a surrogate marker for airway eosinophilia in stable COPD
... for Asthma and Respiratory Diseases PhD Scholarship and Emlyn and Jennie Thomas Postgraduate Medical Research Scholarship through the Hunter Medical Research Institute ... See full document
11
Anselm, Bettina (2019): Early priming of the immune system: Identifying predictive markers of innate immunity and calcium signalling for the development of asthma. Dissertation, LMU München: Medizinische Fakultät
... of asthma [2-4]. While asthma affects patients of every age, its pathogenetic origins most likely lie in the early stages of life ...Subsequently, asthma is considered to be the most common chronic ... See full document
5
Review Article Dry cod skin collagen oligopeptides ameliorate ovalbumin-induced asthma in a mouse model via inhibition of NLRP3 inflammasome
... persistent airway inflammation associated with hyper-responsiveness ...from asthma are relatively low compared with other diseases, it is a protracted illness accompanied by repeated ...an ... See full document
87
Safety of bronchodilators and corticosteroids for asthma during pregnancy: what we know and what we need to do better
... to asthma and pregnancy and, afterwards, to filter out the articles falling outside the scope of the present ...terms asthma, asthma-like symptoms, asthma severity, airway ... See full document
7
Samsoeum water extract attenuates allergic airway inflammation via modulation of Th1/Th2 cytokines and decrease of iNOS expression in asthmatic mice
... the OVA challenge, bronchoalveolar lavage fluid (BALF) samples were obtained from the mice and proc- essed, and inflammatory cells were counted as described previously ...Briefly, mice were ... See full document
24
Silver nanoparticles modify VEGF signaling pathway and mucus hypersecretion in allergic airway inflammation
... from OVA-challenged mice was also ...including asthma, airway mucins may be produced and secreted in greatly increased quantities (mucus ...to airway closure. The principal cells in the ... See full document
5
Original Article A bacterial extract of OM-85 Broncho-Vaxom suppresses ovalbumin-induced airway inflammation and remodeling in a mouse chronic allergic asthma model
... Chronic allergic asthma is characterized by Th2-polarized inflammation, airway remodeling and ...for airway infec- tions in ...chronic asthma remain ...chronic ... See full document
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