[PDF] Top 20 Jurisdicción del trabajo en Panamá
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Deficiency of fibroblast growth factor 21 aggravates obesity-induced atrophic responses in skeletal muscle
... Total RNA was extracted from myotubes or muscle tis- sue samples with Tri-reagent (Life Technologies, Carls- bad, CA, USA). Two microgram aliquots of total RNA were reverse transcribed to cDNA using M-MLV reverse ... See full document
10
Absence of 4-1BB reduces obesity-induced atrophic response in skeletal muscle
... to skeletal muscle atrophy and meta- bolic ...to skeletal muscle atrophy and metabolic dysfunction ...in obesity-induced skeletal muscle ...of atrophic ... See full document
5
Genetic ablation of complement C3 attenuates muscle pathology in dysferlin deficient mice
... the muscle inflam- mation in dysferlinopathy, we next sought to identify the proin- flammatory genes induced by dysferlin ...human skeletal muscles (14, ...skeletal muscle. We performed ... See full document
45
THE STERATEGIC ROLE OF FIBROBLAST GROWTH FACTOR-21IN OBESITY
... including obesity; type 2 diabetes and insulin resis- tance (Cao & Kaufman, ...in responses to oxidative stress (Rahman et ...stressed muscle tissues, white adipose tissue, pancreas, and it also ... See full document
34
Narciclasine attenuates diet-induced obesity by promoting oxidative metabolism in skeletal muscle
... (HFD)-induced obesity in rodents ...diet-induced obesity (DIO) by enhancing energy expenditure without affecting food ...and skeletal muscle, improves blood meta- bolic ... See full document
61
Initiation of vertebrate limb development
... 1994). Duboule has argued that the pattern of cell proliferation and growth is controlled by much earlier expression of Hox genes, and thus, may be the mechanism by which homeosis is achieved (Duboule, 1995). ... See full document
7
Fibroblast growth factor receptor 1 is principally responsible for fibroblast growth factor 2 induced catabolic activities in human articular chondrocytes
... (Collin’s grade > 2) or clinical OA as previously pub- lished [19]. Nevertheless, we do not always observe the same biological effects by FGF-2 using donor tissues from young and normal knee cartilage with Collin’s ... See full document
11
The Characterization of the Fibroblast Growth Factor Receptor Substrate 3 and its role in Regulating Microtubule Dynamics and Molecular Transport in the Brain
... the cortex. Synaptogenesis is the formation of synapses between neurons and occurs as an integration of signaling, recognition, adhesion and protein targeting. This process begins with axonal guidance to the correct ... See full document
9
Extrinsic regulation of satellite cell specification
... Skeletal muscle in all vertebrates originates from cells found in the mesoderm, one of the three primary germ layers ...postmitotic muscle fi bers that will give rise to the organism’s skeletal ... See full document
199
Troglitazone inhibits vascular smooth muscle cell growth and intimal hyperplasia
... multiple growth factors, many which can act through the MAP kinase pathway, may have important therapeutic im- plication since both restenosis and atherosclerosis are complex processes governed by the interaction ... See full document
114
A carnosine analog mitigates metabolic disorders of obesity by reducing carbonyl stress
... HNE induced protein covalent adducts, and its comparison with the known quenchers was then evaluated in a MS-based assay that was recent- ly set up in our laboratory ... See full document
77
Regulation of fibroblast growth factor 15/19 and 21 on metabolism: in the fed or fasted state
... In addition to FGFRs, the FGF19 subfamily members need Klotho (KL) or βKlotho (KLB) protein as a co- receptor to activate their signaling pathway [3] (Fig. 1). KL is a single-pass trans-membrane protein, which has two ... See full document
18
The relationship between non-alcoholic fatty liver and skeletal muscle mass to visceral fat area ratio in women with type 2 diabetes
... The lean body mass of the arms and legs, ASM, as well as VFA were calculated using a dual bioelectrical imped- ance analyzer (BIA) (InBody 720; Biospace, land Seoul, Korea). The analyzer measured resistance at specific ... See full document
5
The effects of obesity on skeletal muscle contractile function
... of skeletal muscle, thereby reducing mobility and promoting obesity-associated health ...how obesity affects skeletal muscle contraction and ...of obesity are disrupted ... See full document
431
Skeletal muscle inflammation and insulin resistance in obesity
... Studies on the effects of obesity on myokine expression are limited and have had inconsistent results. For example, obesity in rats decreased IL-6 and IL-15 expression in SM (30). Similarly, cultured ... See full document
6
Potent mitogenic effects of parathyroid hormone (PTH) on embryonic chick and rabbit chondrocytes Differential effects of age on growth, proteoglycan, and cyclic AMP responses of chondrocytes to PTH
... PTH[1-34] induced a 12- to 15-fold increase in the efficiency of colony formation in soft agar by chondrocytes from embryonic 13- to 19-d-old chickens and fetal 25-d-old rabbits with a 10-fold increase in their ... See full document
11
Peripherally derived FGF21 promotes remyelination in the central nervous system
... Circulating FGF21 promotes OPC proliferation. Because vas- cular barrier disruption causes leakage of circulating factors into the CNS (16), we hypothesized that the leaked circulating factors stimulate OPC ... See full document
148
Global expression profile of tumor stem-like cells isolated from MMQ rat prolactinoma cell
... Microarray systems were broadly used to investigate gene expression patterns and functional classification in stem cell [19]. In this paper, to evaluate the gene dif- ferences between MMQ cells and tumor stem-like cells, ... See full document
28
Sleeve gastrectomy attenuates high fat diet-induced non-alcoholic fatty liver disease
... Results: Postoperatively, body weights in the HFD + SHAM and HFD + SG group rats decreased during the first week. Thereafter, HFD + SG rats regained their body weight. Differences in insulin, homeostasis model assessment ... See full document
18
Myositis associated with a newly described microsporidian, Trachipleistophora hominis, in a patient with AIDS
... in skeletal muscle with central atrophied fibers (arrow) and outer fibers filled with basophilic spores and spore precursors (arrowheads) (H and E stain; magnification, 3 ...in skeletal muscle ... See full document
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