[PDF] Top 20 La participación ciudadana como instrumento del gobierno abierto

... Early cancer detection is crucial for a successful cancer ...various cancer diagnostic methodologies are available, it is unfortunate that these methods do not fully meet the demand of early ... See full document

... breast cancer [12]. Mutations and deletions in the human MALAT1 gene were recently discovered in luminal breast cancer [13, ...tissue, MALAT1 expression was up-regulated significantly in ... See full document

... “ MALAT1 ” and “ sensitivity ” or “ speci fi city ” or “ ROC curve ” or “ accuracy ” ...lncRNA MALAT1 for detecting cancer evaluated in stu- dies; (3) the number of true positive (TP), false positive ... See full document

... the MALAT1 levels in cancerous tis- sues were significantly higher than those in noncancerous tis- sues, suggesting a positive role for MALAT1 in CRC tumourigene- ...cervical cancer cells, deple- ... See full document

... of MALAT1 in the EMT process in breast ...of MALAT1 promoted migration and invasion of breast cancer cells in vitro and further indicated that lower MALAT1 expression was linked to metastasis ... See full document

... Notably, MALAT1 was only up-regulated in GC/ ...of MALAT1 in gastric cancer remain ...gastric cancer [24]. The presented data indicated that plasma level of MALAT1 was negatively ... See full document

... fact MALAT1 is expressed ubiquitously but fulfills tissue- specific functions depending on the cellular environment ...Commonly, MALAT1 is analyzed in tissues [14-16], whereas in this study and the study of ... See full document

... colon cancer patients might provide evidence for supporting the potential role of Dkk3 as a tumor marker for diagnosis, prognosis, and monitoring of CRC, as statis- tical analysis revealed that serum level ... See full document

... Although there is research which has proved that circRNA plays an important role in oncogenesis and in fl uences the proliferation, migration, and apoptosis in different cancer, the function of most circRNAs is ... See full document

... pancreatic cancer, identification of miRNA signatures differentially expressed in different pathological stages of the disease may distinguish pancreatic cancer from pancreatic benign diseases with ... See full document

... Previous studies have revealed the oncogenic and tumor suppressor roles of miRNAs during the formation and progression of tumors through the pathway modula- tion. Furthermore, several miRNAs have been reported closely ... See full document

... of MALAT1 in IDH1/2 wild-type primary GB ...of MALAT1 was detected in the 75 primary GB tissues and 5 normal brain tissues using reverse transcription quantitative PCR ...between MALAT1 expression, ... See full document

... breast cancer, which implies that it could be a useful biomarker in the early detection of breast ...breast cancer was assessed using pooled sensitivity and specificity, diagnostic odds ratio (DOR), ... See full document

... of cancer, such as HOTAIR, MALAT-1 and H19 have been implicated as playing a func- tional rolein carcinogenesis or cancer growth ...lncRNA MALAT1 was increased in colorectal cancer compared to ... See full document

... Herein, TIMP1 is identi fi ed to be consistently upregulated in the initiation and progression of ucaCRC and can also be a potential biomarker for the prognosis of patients with CRC based on the integrative ... See full document

... Here, a novel TSG was evaluated. LZTS2 is located at human 10q24.3, is expressed in most normal tissues [8], suppresses cell growth by interacting with β-catenin [11], and plays a vital role in the carcinogenesis and ... See full document

... of cancer-prone inflammatory diseases caused by various pathogens, including human papillomavirus and Epstein–Barr ...a potential biomarker to evaluate the risk of inflammation-related carcinogenesis ... See full document

... splicing factor SRSF1 bridges MALAT1 to mutant p53 and ID4 proteins in breast cancer cells... Mutant p53 and ID4 delocalize MALAT1 from nuclear speckles and favor its association with.[r] ... See full document

... between MALAT1 and MIR376A expression in OS tissues. Knock-down of MALAT1 upregulated MIR376A, while overexpression of MIR376A inhibited MALAT1 expression in vitro, suggesting a direct association ... See full document

... gastric cancer tissues, the High-HOTAIR group was associated with venous invasion, lymph node metastases and lower overall sur- vival rate compared to the Low-HOTAIR group ...lncRNA MALAT1 was increased in ... See full document