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Vaccination with recombinant adenovirus expressing peste des petits ruminants virus-F or -H proteins elicits T cell responses to epitopes that arises during PPRV infection
... putative PPRV T cell epitopes was also explored in ...after PPRV (IC’89) ...towards PPRV [23], sheep PBMC from both groups were used in these ...predicted, T cell ... See full document
20
The 135 Gene of Goatpox Virus Encodes an Inhibitor of NF-κB and Apoptosis and May Serve as an Improved Insertion Site To Generate Vectored Live Vaccine
... Goatpox virus (GTPV) is an important member of the Capripoxvirus ge- nus of the ...unknown proteins that may contribute to ...a recombinant AV41 strain expressing hemagglutinin of peste ... See full document
191
Recombinant adenovirus expressing the haemagglutinin of peste des petits ruminants virus (PPRV) protects goats against challenge with pathogenic virus; a DIVA vaccine for PPR
... against PPRV could be elicited by expression of just the viral ...glycoproteins. Recombinant vaccinia virus expressing F and H proteins of rinderpest virus (RPV), ... See full document
8
Development and Characterization of a Stable Vero Cell Line Constitutively Expressing Peste des Petits Ruminants Virus (PPRV) Hemagglutinin Protein and Its Potential Use as Antigen in Enzyme-Linked Immunosorbent Assay for Serosurveillance of PPRV
... of infection and the implementation of prompt con- trol ...to PPRV. Surface proteins of morbilliviruses are epidemiologically im- portant because they are the proteins most exposed to the ... See full document
129
Development of a Dual Recombinant Vaccine To Protect Small Ruminants against Peste-des-Petits-Ruminants Virus and Capripoxvirus Infections
... this virus group have a host range specific to sheep (sheeppox), goats (goatpox), or cattle (lumpy skin disease), and attenuated vaccines are already available to control cap- ripoxvirus infections ...of ... See full document
10
Determination of the minimum fully protective dose of adenovirus-based DIVA vaccine against peste des petits ruminants virus challenge in East African goats
... of PPRV [6, 7]; these vaccines are effec- tive, though they do not provide a DIVA (distinguishing infected from vaccinated animals) ...subclinical infection with PPRV, and therefore the antibody ... See full document
8
Spillover of Peste des Petits Ruminants Virus from Domestic to Wild Ruminants in the Serengeti Ecosystem, Tanzania
... tested during 2008–2010 for the Somali Ecosystem Rinderpest Eradication Coordination Unit program, also showed seronegative results for PPRV ...opportunistically during other research activities in ... See full document
145
Protection of Cattle against Rinderpest by Vaccination with Wild-Type but Not Attenuated Strains of Peste des Petits Ruminants Virus
... Antibody responses in RPV-challenged ...the PPRV-inoculated animals that survived, whether measured as RPV-neutralizing antibody ...to vaccination with PPRV strains or RPV ...different ... See full document
8
Development of real time and lateral flow strip reverse transcription recombinase polymerase Amplification assays for rapid detection of peste des petits ruminants virus
... Different cell lines have been used to isolate PPRV but with limited success [7, ...to virus isolation ...of PPRV, however, its sensitivity was not good enough to detect PPRV in ... See full document
58
Morbillivirus Downregulation of CD46
... of H-antigen expression on their surfaces, as indicated by the peaks of fluorescence intensity for the infected and unin- fected cell populations ...same cell types showed a much lower level of CD46 ... See full document
Comparison of the Immunogenicities and Cross-Lineage Efficacies of Live Attenuated Peste des Petits Ruminants Virus Vaccines PPRV/Nigeria/75/1 and PPRV/Sungri/96
... automated cell counter, and the cells were either used immediately or stored frozen over liquid nitrogen in 90% FBS–10% dimethyl sulfoxide until ...of T cell IFN-␥ responses; fresh cells were ... See full document
254
CONCURRENT INFECTION OF PESTES DES PETITS RUMINANTS AND ENTEROTOXAEMIA IN AN ORGANIZED GOAT FARM
... Enterotoxaemia is reported almost every year from several part of India during the pre-monsoon season (Vinod Kumar et al., 2014). Epsilon toxin produced by C. perfringens is attributed to enterotoxaemia (Nasir et ... See full document
22
Susceptibility of Moroccan sheep and goat breeds to peste des petits ruminants virus
... goats. During the 2008 PPR out- break in Morocco, characteristic signs of the disease were observed only in young animals of some local sheep and goat ...of PPRV exposure [17–19]. Resistant animals are ... See full document
308
Characterization of Ovine Nectin-4, a Novel Peste des Petits Ruminants Virus Receptor
... where PPRV replication is common, such as the lungs and lower intestinal tract, was very low ...for PPRV FIG 1 Ovine Nectin-4 can function as a receptor for ...encephalomyocarditis virus internal ... See full document
22
CpG-Containing Oligonucleotides Are Efficient Adjuvants for Induction of Protective Antiviral Immune Responses with T-Cell Peptide Vaccines
... the cell surface of B cells correlated with their ability to activate B ...protective T-cell immunity against challenge in- fection with lymphocytic choriomeningitis virus (LCMV) and ... See full document
11
Development of a helper cell-dependent form of peste des petits ruminants virus: a system for making biosafe antigen
... of PPRV N mRNA or host cell L13A mRNA was carried out essentially as previously de- scribed [18,27], using a set of primers recognising the PPRV N gene and optimised for SYBR Green-based qPCR ... See full document
76
Detection and genetic characterization of lineage IV peste des petits ruminants virus in Kazakhstan
... Kock, R. A., Orynbayev, M. B., Sultankulova, K. T., Strochkov, V. M., Omarova, Z. D., Shalgynbayev, E. K., Rametov, N. M., Sansyzbay, A. R. and Parida, S. (2015), Detection and Genetic Characterization of Lineage ... See full document
6
Molecular Epidemiology Of Peste Des Petits Ruminants (PPR) In Goat
... Peste des petits ruminants (PPR) is an endemic disease of goat, caused by RNA virus of the genus Morbillivirus that was first described by [1] from Ivory ...PPR virus. The ... See full document
22
Development and Testing of a Field Diagnostic Assay for Peste des Petits Ruminants Virus
... Peste des petits ruminants (PPR) is a viral disease of sheep and goats which has shown rapid spread throughout large parts of the developing world in the last 20 years (Banyard et ... See full document
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1. Peste des petits ruminants: A review
... Disease is tentatively diagnosed by clinical observations, post-mortem lesions and laboratory confirmation by several serological and molecular techniques including PPRV detection by specific antibody in serum, ... See full document
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