[PDF] Top 20 Há efeitos da reabilitação pulmonar sobre o risco cardiovascular em pacientes com doença pulmonar obstrutiva crônica?
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Evidence That Quinine Exhibits Antiviral Activity against SARS-CoV-2 Infection In Vitro
... of SARS- CoV-2 infection, the medical need to prevent the transition of a mild into the severe COVID-19 stage of infection is of outmost ...substance Quinine, a medicinal product ... See full document
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Antiviral Activity of Trappin-2 and Elafin In Vitro and In Vivo against Genital Herpes
... Tr against HIV-1, and that Tr/E inhibited HIV-1 attachment and transcytosis across human geni- tal epithelial cells ...virus 2 (HSV-2) is a major sexually transmitted infection and risk factor ... See full document
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Chloroquine as a Potential Treatment and Prevention Measure for the 2019 Novel Coronavirus: A Review
... coronavirus infection as well as the mechanism of CQ that serve as evidence of its possible ...in vitro and in ...prevent infection in healthcare providers and vulnerable populations, as well ... See full document
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Severe Acute Respiratory Syndrome Coronavirus Infection of Human Ciliated Airway Epithelia: Role of Ciliated Cells in Viral Spread in the Conducting Airways of the Lungs
... of SARS-CoV infection in these ...in vitro does not result in cultures that are significantly different in terms of differentiation or morphology from cultures grown for 3 to 5 days ...tract ... See full document
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Mycophenolate Mofetil Is Active Against SARS-CoV-2 in Vero E6 Cells
... potency against SARS-CoV-2 in Vero E6 cells, its good pharmacokinetics and clinical safety profile, mycophenolate mofetil deserves further exploration as potential treatment for ... See full document
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Structural Similarity Analysis of Spike Proteins of SARS-CoV-2 and Other SARS-related Coronaviruses
... with SARS- CoV-2, with 96% identity at the whole-genome level ...between SARS-CoV-2 and other SARS-related other ...of SARS-CoV-2 was found to be very ... See full document
5
Revealing the Potency of Citrus and Galangal Constituents to Halt SARS-CoV-2 Infection
... on SARS-CoV-2 marker protein, RBD-S, PD-ACE2, and SARS-cov-2 ...of SARS-CoV-2. For the crystal structure of SARS-CoV-2 protease, PDB ID ... See full document
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Lung Adenocarcinoma Patients Own Higher Risk of SARS-CoV-2 Infection
... enzyme 2 (ACE2), a terminal carboxypeptidase, catalyzes the conversion of angiotensin II (Ang II) to angiotensin 1-7 (Ang ...for SARS-CoV [7, ...the SARS-CoV S glycoprotein [10]. ... See full document
6
Feasibility of Known RNA Polymerase Inhibitors as Anti-SARS-CoV-2 Drugs
... Resistance to remdesivir has been demonstrated in in vitro passage assays [55]. Two mutations (F476L and V553L) in MHV nsp12 appeared after 23 passages. Amino acid residues F476 and V553 are numbered F483 and ... See full document
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In vitro antiviral activity of twenty seven medicinal plant extracts from Southwest Nigeria against three serotypes of echoviruses
... highest antiviral activity, it was subjected to vacuum liquid chro- matography (VLC) on silica gel using a gradient elution solvent system that comprised of n-hexane/EtOAc (10:1 to 5:5, each 250 ... See full document
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SARS-CoV-2 ORF8 and SARS-CoV ORF8ab: Genomic Divergence and Functional Convergence
... in SARS-CoV-2: COVID-19 has spread at an extremely fast rate in terms of both space and ...the SARS-CoV-2 genome have been reported so ...from SARS-CoV-2 ... See full document
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COVID-19: Considerations for Children and Adolescents with Diabetes
... to SARS-CoV- 2 may cause transient impairment of pancreatic islet cell function or modulate the action of insulin via anchoring to host cells via dipeptidyl peptidase 4 ...and 2-hour ... See full document
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Lambda Interferon (IFN-λ), a Type III IFN, Is Induced by Viruses and IFNs and Displays Potent Antiviral Activity against Select Virus Infections In Vivo
... the activity of type III IFN in vivo by evaluating the antiviral activity of recombinant IFN- 2 against three different systemic viral infections, we observed that the cytokine ... See full document
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O-β-GlcNAcylation, Chloroquine and 2-Hydroxybenzohydrazine may hamper SARS-CoV-2 entry to human via inhibition of ACE2 phosphorylation at Ser787 but also induce disruption of virus-ACE2 binding
... To inhibit the phosphorylation of ACE2 at Ser-787, we have proposed two inhibition mechanisms i) inhibition through PTMs and (ii) inhibition through drug binding. Post translational modifications (PTMs) at specific ... See full document
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Possible Cross-Reactivity Between SARS-CoV-2 Proteins, CRM197 and Proteins in Pneumococcal Vaccines May Protect Against Symptomatic SARS-CoV-2 Disease and Death
... also exhibits some high-quality antigenic similarities to ...and SARS-CoV-2, and their key results were independently reproduced here in FIGURE ...of SARS-CoV-2 proteins ... See full document
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Cellular Immune Responses to Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) Infection in Senescent BALB/c Mice: CD4+ T Cells Are Important in Control of SARS-CoV Infection
... (5⬘-TCTCCTGTGGATCGGGTATAGAC-3⬘), CXCR3 forward (5⬘-GCTAGA TGCCTCGGACTTTGC-3⬘) and CXCR3 reverse (5⬘-CGCTCTCGTTTTCCCC ATAA-3⬘), CCL2 forward (5⬘-GCTGGAGCATCCACGTGTT-3⬘) and CCL2 reverse (5 ⬘ -ATCTTGCTGGTGAATGAGTAGCA-3 ⬘ ... See full document
127
Overview of the Management of COVID-19 Efficacy and Doubts
... of SARS‐CoV‐2 nucleic acid test kit have been developed and approved ...virus infection, which is harmful for the control of infectious diseases ...warned against non-approved measure ... See full document
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Induction of Specific Immune Responses by Severe Acute Respiratory Syndrome Coronavirus Spike DNA Vaccine with or without Interleukin-2 Immunization Using Different Vaccination Routes in Mice
... of SARS was identified as a new coronavirus (CoV), named SARS-CoV (13, 22, 29, ...The SARS-CoV genome is approximately 29,000 bp and encodes four main structure proteins, ... See full document
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SARS-CoV-2 infection of cats and dogs?
... out SARS-CoV-2 intermediate hosts and to figure out the transmission model of SARS-CoV-2 and finally to control the COVID-19 ... See full document
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Assessment of Anti HSV-1 Activity of Aloe Vera Gel Extract: an In Vitro Study
... of antiviral activity of different herbal extract is in the viewpoint of several investiga- ...the antiviral properties of Aloe vera against HSV-2 [1] however; there is no data on ... See full document
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