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The transduction of mouse hematopoietic stem cells with the LV:Chim.hCD18 does not result in the mobilization or shedding of the

GENE THERAPY

III. ANALYSIS OF THE FUNCTIONS OF HUMAN HEMATOPOIETIC STEM CELLS TRANSDUCED WITH THE THERAPEUTIC LV:CHIM.HCD18 UNDER

2. The transduction of mouse hematopoietic stem cells with the LV:Chim.hCD18 does not result in the mobilization or shedding of the

Scenario

Since A. Datum is a global brand, you want to ensure that the A. Datum website responds rapidly to requests from multiple locations around the world. You have been asked to evaluate the Azure Traffic Manager to see if it can ensure web content is served from a location close to users. You want to set up Traffic Manager to serve content from two different Azure regions.

The main tasks for this exercise are as follows:

1. Deploy a Website to Another Region 2. Create a Traffic Manager Profile

3. Add Endpoints and Configure Traffic Manager 4. Test Traffic Manager

5. Reset the Environment

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Implementing Microsoft Azure Infrastructure Solutions 5-37

 Task 1: Deploy a Website to Another Region

1. In Windows Azure PowerShell, get a list of all the websites in your Azure subscription. Note the name of your original website.

2. Get a list of the Azure locations and chose a location that is not the location you chose in Exercise 1.

3. Create a new website. Use the following information:

o Name: Use the name of your original website with the number 2 appended.

o Location: Use the location you chose in step 2.

4. In the Azure full portal, download a publish profile for the website you just created (WebsiteName2).

5. Open the following project in Visual Studio:

o D:\LabFiles\Lab05\Starter\AdatumWebsite\AdatumWebsite.sln

6. Start the Publish Web wizard and import the publish settings file you just downloaded.

Note: Be sure to add a new publish settings file on the Profile tab, so that the content can be published to the new website.

7. Validate the connection and choose the Release configuration.

8. Publish the website. Close Internet Explorer and Visual Studio.

9. In the Windows Azure full portal, configure the new website in the Standard tier.

 Task 2: Create a Traffic Manager Profile

1. Use the Test-AzureTrafficManagerDomainName cmdlet in Windows Azure PowerShell to determine an available domain name to use in this Exercise.

2. In the full Azure portal, create a new Traffic Manager profile. Use the following information:

o DNS Prefix: Use the domain name you chose in step 1 o Load Balancing Method: Performance

 Task 3: Add Endpoints and Configure Traffic Manager

1. Add the websites you created in Exercise 1 and Exercise 4 as endpoints in the Traffic Manager profile.

2. Configure the DNS time to live value to be 30 seconds.

 Task 4: Test Traffic Manager

1. Browse the traffic manager URL you created in Task 2.

2. Use the nslookup command to resolve the DNS NAME for your traffic manager profile.

Note: In the DNS aliases, traffic manager returns the website you created in Exercise 1, which is closest to your physical location.

3. In the Azure portal, disable the traffic manager endpoint that is the website you created in Exercise 1.

4. Use the nslookup command to resolve the DNS NAME for your traffic manager profile. The results should differ from those in step 3.

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5-38 Implementing Websites

Note: If the aliases have not changed, reissue the nslookup commands until there is a change.

 Task 5: Reset the Environment

1. Close all open applications without saving any files.

2. On the taskbar, right-click Microsoft Azure PowerShell, and then click Run as administrator. In the User Account Control dialog, click Yes.

3. Type the following command, and then press Enter:

Reset-Azure

4. When prompted, sign in using the Microsoft account associated with your Azure subscription.

Note: This script may remove Azure services in your subscription. It is therefore recommended that you use an Azure trial pass that was provisioned specifically for this course, and not your own Azure account.

The script will take 5-10 minutes to reset your Microsoft Azure environment, ready for the next lab.

The script removes all storage, VMs, virtual networks, cloud services, websites, and resource groups.

Important: The script may not be able to get exclusive access to a storage account to delete it (if this occurs, you will see an error). If you find objects remaining after the reset script is complete, you can re-run Reset-Azure script, or use the full Azure Management Portal to manually delete all the objects in your Azure subscription, with the exception of the default directory.

Results: At the end of this exercise, you will have a website set up in two Azure regions and Traffic Manager will be configured to distribute requests between them.

Question: In Exercise 2, you deployed the A. Datum production website to Azure. In Exercise 3, you deployed a new version of the site to a staging slot. How can you tell, within Internet Explorer, which is the production site and which is the staging site?

Question: At the end of Exercise 4, you used an FQDN within the trafficmanager.net domain to access your website. How can you use your own registered domain name to access this website?

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Implementing Microsoft Azure Infrastructure Solutions 5-39

Module Review and Takeaways

In this module, you learned about:

 Choosing hosting plans and deployment methods for Azure websites.

 How administrators can deploy a completed web application to Windows Azure.

 How to configure websites for best performance and use WebJobs.

 How to monitor website activity.

 How to use Traffic Manager to distribute requests for a website in Azure.

Review Question(s)

Question: What are the advantages of deploying a website to Azure Websites over those of deploying a website to an Azure VM running IIS?

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6-1

Module 6