Fibras de vidrio - Propiedades mecánicas - Investigaciones
CD95 induced osteoarthritic chondrocyte apoptosis and necrosis: dependency on p38 mitogen activated protein kinase
... We have also shown that activation of the CD95 pathway in chondrocytes increases not only the cell death rate but also the production of CD95L by chondrocytes. The initial induc- tion of cell death in cartilage by ...
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Von willebrand factor increases endothelial cell adhesiveness for human mesenchymal stem cells by activating p38 mitogen-activated protein kinase
... of p38 MAPK (Thr180/Tyr182) and ERK-1,2 (Thr202/Tyr204) was assayed using corre- sponding cell-base ELISA kits (R&D ...total protein kinase at 450 nm and phosphorylated protein ...
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Hypertonicity regulates the function of human neutrophils by modulating chemoattractant receptor signaling and activating mitogen activated protein kinase p38
... MAPK p38 is involved in HS-enhanced enzyme ...of p38 could play a role in the HS-induced upregulation of ...specific p38 inhibitor ...that p38 is at least in part involved in the activation of ...
188
The anti-proliferative and anti-inflammatory response of COPD airway smooth muscle cells to hydrogen sulfide
... and p38 MAPK We have previously reported that ...and p38 MAPK in ASM cells from non-smokers and that this is prevented by NaSH ...of p38 MAPK phosphorylation in cells from smokers and COPD patients ...
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Epstein-Barr Virus Infection Induces Indoleamine 2,3-Dioxygenase Expression in Human Monocyte-Derived Macrophages through p38/Mitogen-Activated Protein Kinase and NF-κB Pathways: Impairment in T Cell Functions
... CD8 ⴙ cytotoxic T lymphocytes (CTLs) play an important role in the control of viral infections and destroy tumor cells. Activa- tion of the tryptophan-catabolizing enzyme indoleamine 2,3-dioxygenase (IDO) in cancer ...
218
Kinase Activity Profiling of Gram-Negative Pneumonia
... approach. Kinase activity arrays enable the analysis of 1,024 con- sensus sequences of protein kinase ...a kinase activity array on whole lung lysates, cellular kinase activities were ...
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Chondrocyte response to growth factors is modulated by p38 mitogen activated protein kinase inhibition
... when p38 MAPK is ...by p38 MAPK inhibitors may contribute to their ability to blunt the anti-anabolic actions of ...selective p38 MAPK inhibitor, did not decrease IL-1 induction of iNOS and NO ...
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Retinoic Acid Attenuates Oxidative Injury in Bovine Mammary Epithelial Cells Induced by Hydrogen Peroxide
... for mitogen-activated protein kinase (MAPK) and can be phosphorylated and activated by MAPK under oxidative stress, resulting in the production of large amounts of ARA (Zhu et ...
183
Novel interconnections of HOG signaling revealed by combined use of two proteomic software packages
... conserved protein [85] is crucial for coordinating lipid homeostasis [86, 87] and is respon- sive to ER- and heat-stress in ...Orm-like protein (ORMDL)-regulated cellular levels of sphingolipids have been ...
133
Epithelial cell senescence impairs repair process and exacerbates inflammation after airway injury
... of p38 MAPK in the Clara cells of COPD patients, corrobor- ating a previous study showing increased numbers of phospho-p38 MAPK-positive macrophages and phospho- p38 MAPK-positive alveolar cells in ...
5
Tumour necrosis factor activates the mitogen activated protein kinases p38α and ERK in the synovial membrane in vivo
... fusion protein; Amgen), which is a blocker of the interaction between receptor activa- tor of nuclear factor- κ B (RANK) ligand and RANK, at a dose of 10 mg/kg three times weekly by intraperitoneal injection [20]; ...
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p38 Mitogen-activated protein kinase modulates exocrine secretion in rabbit lacrimal gland
... The kinase p38 has important signal transduction functions, ...of p38 in carbachol (Cch)-induced LG secretion in LG acinar cells in ...of p38 and p42/44 and determine expression of p38 ...
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Molecular responses to abiotic stress and the development of drought tolerance in plants
... A gene encoding a mitogenactivated protein kinase kinase kinase is induced simultaneously with genes for a mitogen-activated protein kinase and an S6 ribosomal protein kinase by touch, c[r] ...
6
Divergent roles for Ras and Rap in the activation of p38 mitogen activated protein kinase by interleukin 1
... of p38 mitogen-activated protein kinase (MAPK) by interleukin-1 (IL-1) in ...target protein involved appeared to be Ras, because transient transfections with dominant neg- ative RasN17 ...
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The effect of orofacial complete Freund’s adjuvant treatment on the expression of migraine-related molecules
... results are consistent with observations from animal in- vestigations where the CFA induced chronic pain-like behaviour 3 days after treatment [12, 14, 34]. Addition- ally, it was also demonstrated that chronic ...
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p38 mitogen-activated protein kinase determines the susceptibility to cigarette smoke-induced emphysema in mice
... a p38 MAPK inhibitor in a murine model of CS exposure ...of p38 MAPK inhibitors is sufficient to prevent emphysema de- ...inhibit p38 MAPK for such a prolonged ...lung protein of KC, MIP-1α, ...
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p38 mitogen-activated protein kinase is involved in arginase-II-mediated eNOS-Uncoupling in Obesity
... The Arg-II -/- mice were kindly provided by Dr. William O’Brien [26] and backcrossed to C57BL/6 J for more than ten generations [12]. Genotyping was performed by polymerase chain reaction (PCR) as previously described ...
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Correlation between p38 mitogen-activated protein kinase and human telomerase reverse transcriptase in sarcomas
... MAP kinase can regulate hTERT ...MAP kinase cascades ...the mitogen signaling pathways of MAP kinase, regulates hTERT ...[31]. p38 MAPK may play an important role in the activation of ...
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Identification and Characterization of MAPK Phosphorylation Sites in Runx2
... kinase activation (FAK) (Franceschi and Xiao, 2003), certain non-genomic actions of estrogens (Kousteni et al., 2003) and mechanical stimulation mediated by FAK activation (Moalli et al., 2001) and connexin 43 ...
48
Glucose or diabetes activates p38 mitogen activated protein kinase via different pathways
... increased p38 MAP kinase activ- ities in parallel with elevation of DAG levels by de novo synthesis in pancreatic β ...and p38 MAP ...and p38 MAP kinase activities when the activators ...
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