[PDF] Top 20 Caracterización de la mortalidad en cirugía cardiaca.

... Interestingly, sorafenib upregulated MiRNA423-5p both in vitro and in vivo and its increase from baseline to evaluation at 6 months correlated with ...of patients with miR423-5p level increase achieved a ... See full document

... Seventy-eight patients with advanced or intermediate stage HCC that was refractory or no longer amenable to locoregional therapies (according to American Association for the Study of Liver Diseases ... See full document

... Introduction: Sorafenib is an orally active multikinase inhibitor approved for the treatment of advanced hepatocellular carcinoma (HCC) and is the only systemic treatment associated with a survival benefit ... See full document

... risk factors of younger males, as well as alcohol ...of HCC was ...of HCC might have a potential genetic susceptibility, or share similar living habits ...elderly patients have a lower tumor ... See full document

... of patients with HCC ...in sorafenib treated HCC, indicating that T cell receptor signaling pathway may involve in ...many factors such as leptin and adiponectin ...of HCC ... See full document

... solitary HCC. The two models that enabled risk assess- ment of HCC recurrence before and after resection exhib- ited superior discrimination, with C-index of ...stratifying patients into two ... See full document

... separate patients into good and unfavorable prognosis cohorts ...2 patients’ group with differ- ent DMFS (Ki-67 15% p = ...logical factors except pT status (p = ... See full document

... presently sorafenib remains the gold standard of treatment for advanced, unresectable HCC and provides modest improvement in survival, treatment options for HCC are increasing, and patient selec- ... See full document

... stomatitis. Patients were treated until disease progression, unacceptable toxicity, investiga- tor’s decision to discontinue treatment, or withdrawal of con- sent or ... See full document

... 561 HCC patients treated in the NCI during the study ...of HCC was based on the European Association for the Study of the Liver (EASL) and European Organization for Research and Treatment of ... See full document

... Prognostic factors correlate with outcome independent of treatment ...effect. Predictive factors inform on the probability of response to a treatment and therefore are more useful in helping ... See full document

... of sorafenib, a multikinase inhibitor, in RCC has been previously confirmed in Phase II and Phase III trials, leading to its approval by the US Food and Drug Administration in December 2005 as the first targeted ... See full document

... in patients with HCC and mild cirrhosis (Child A) compared to those with moderate or advanced cirrhosis (Child B/C) (Child A vs Child B/C, OR = ...of HCC are depicted in Figure 6 and summarized in ... See full document

... Preoperative diagnosis is essential for characterization of uterine tumors to determine the safest therapeutic strategy. Minimally invasive techniques, including laparoscopic intervention, morcellation, myomectomy and ... See full document

... in patients with digestive system neo- ...7,308 patients, from China, Korea, Japan, the UK, Switzerland, and Germany, were ...of patients in each study ranged from 40 to ...in patients with ... See full document

... risk of cardiotoxicity for dasatinib and lapatinib. An analysis of guidelines and professional recommendations identifies routine monitoring of heart function during therapy and iden- tification of at risk ... See full document

... of patients par- ticipating in the clinical trial BIG ...of patients and methods in this trial have been described previously by Francis et ...2001, patients were randomly assigned at a ratio of ... See full document

... primary HCC; a high SUV ratio sig- nifies more malignant tumors and, thus, a worse prognosis ...good prognostic factor and Song et ...better prognostic factor ...in HCC should be a useful ... See full document

... CRPC patients, the authors showed that docetaxel re-treatment preserves antitumor activity and is well tolerated in a selected population of pretreated patients with CRPC ... See full document

... Thus, the goal of our study was to determine whether elderly patients benefit from individualized treatment not excluding full standard therapy and prognostic and predictive factors infl[r] ... See full document