[PDF] Top 20 Comercio informal: un caso en Ensenada, Baja California
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Crocin induced apoptosis through p53-dependent pathway in C6 glioma Cells
... that crocin treatment inhibited cell proliferation and induced cell death in C6 ...that crocin initiates the process of apoptosis in C6 glioma ...cells. p53 ... See full document
9
Activation of neutral-sphingomyelinase, MAPKs, and p75 NTR-mediating caffeic acid phenethyl ester–induced apoptosis in C6 glioma cells
... CAPE induced MAPKs activation, we assessed whole cell lysates from CAPE-treated C6 cells by western blotting analysis (Figure ...the apoptosis of C6 cells. We found that ... See full document
65
Mechanisms of tumor necrosis factor-α-induced interleukin-6 synthesis in glioma cells
... is dependent on the IB- NFB pathway ...in C6 glioma cells. TNF- a significantly induced the phosphorylation of NFB at Ser 536 and Ser 468, but not at Ser 529 and Ser ...rat ... See full document
148
Crosstalk between the IGF-1R/AKT/mTORC1 pathway and the tumor suppressors p53 and p27 determines cisplatin sensitivity and limits the effectiveness of an IGF-1R pathway inhibitor
... increasing p53 is to induce either apoptosis or transient/permanent cell cycle ...arrest. Apoptosis or permanent cell cycle arrest (senescence) are bona-fide tumor suppressor mechanisms ... See full document
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Activated Notch1 Inhibits p53-Induced Apoptosis and Sustains Transformation by Human Papillomavirus Type 16 E6 and E7 Oncogenes through a PI3K-PKB/Akt-Dependent Pathway
... HaCaT cells induces resistance to anoikis (apoptosis induced on matrix withdrawal) and sustains colony formation by HPV-16 E6 and E7 oncogenes in soft-agar assays ...mutant p53 alleles and ... See full document
26
Molecular mechanism leading to SAHA-induced autophagy in tumor cells: evidence for a p53-dependent pathway
... The apoptosis-inducing functions of p53 are exerted in two ways: one is through the transcriptional activation of pro-apoptotic proteins such as Puma, Noxa and Bax, the other is via direct physical ... See full document
134
Mesothelin regulates growth and apoptosis in pancreatic cancer cells through p53-dependent and -independent signal pathway
... cancer cells, forced expression of mesothelin significantly increased tumor cell proliferation and migration by 90% and 300%, respectively, and increased tumor volume by 4-fold in the nude mice xenograft model ... See full document
5
Metabolomics profiles delineate uridine deficiency contributes to mitochondria-mediated apoptosis induced by celastrol in human acute promyelocytic leukemia cells
... metabolism pathway (Supplementary Table ...metabolic pathway (Figure 3D and Supplementary Table ...of p53 by preventing its degradation [26], which can well explain the inconsistence between mRNA and ... See full document
120
Ethanol Extract of Annona Muricata. L Induces Liver Cancer Cell Apoptosis Through ROS Pathway
... We analyzed whether the herbal extract could generate ROS in HepG2 cells by comparing ROS level amongst control, treatment (120 µg/ml of extract) and antioxidant (120 µg/ml extract plus 5 mM NAC) groups. As shown ... See full document
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<p>A Review of Research Progress in Multidrug-Resistance Mechanisms in Gastric Cancer</p>
... tumor cells in chemotherapy, promoting drug resistance as ...is induced by conventional genotoxic agents, such as radiation or cisplatin, as a result of DNA damage- induced p53 ...of ... See full document
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<p>Active Monomer RTR-1 Derived from the Root of <em>Rhodomyrtus tomentosa</em> Induces Apoptosis in Gastric Carcinoma Cells by Inducing ER Stress and Inhibiting the STAT3 Signaling Pathway</p>
... gastric cells, the Cyclin B/cdc2 complex has an important function in controlling the G2/M ...damage, cells activate a signaling network to arrest the cell cycle and facilitate DNA repair, which inhibits ... See full document
150
PCV2 replication promoted by oxidative stress is dependent on the regulation of autophagy on apoptosis
... Autophagy is an evolutionarily conserved catabolic process involved in the degradation and recycling of cytoplasmic components. It plays an essential role in nor- mal development and responds to changing environmen- tal ... See full document
18
CELLFOOD™ induces apoptosis in human mesothelioma and colorectal cancer cells by modulating p53, c-myc and pAkt signaling pathways
... pathways through which they act ...part, through Akt activation via the phosphatidyli- nositide 3′-OH kinase (PI3K) signaling ...Moreover, induced Akt activity (p-AKT) (due to overexpression) is ... See full document
11
Original Article Metformin induces apoptosis of osteosarcoma U2OS and 143B cells through the mitochondria-dependent pathway and potentiates the anti-neoplastic activity of cisplatin in vivo
... cancer cells via suppressing tumor invasion and reversing the cisplatin resistance ...143B cells apoptosis and attenuated tumor xenografts via mitochondria-mediated signal ...metformin- ... See full document
172
CALCIUM MODULATORY EFFECTS OF CROCIN FROM SAFFRON (CROCUS SATIVUS L.) IN C6 GLIOMACELLS
... Hepes). Cells were then incubated at 37°C in the above buffer with 5 μM fura-2 AM for 30 min in ...the cells were washed three times with the same buffer solution but without fura-2 AM at ...signal, ... See full document
6
Original Article 3-aminobenzamide, one of poly(ADP-ribose) polymerase-1 inhibitors, rescuesapoptosisin rat models of spinal cord injury
... of apoptosis induced by SCI, a kind of massive DNA damage frequently leading to PARP-1 ...apoptotic pathway (cas- pase dependent apoptotic process), PARP-1 is proteolytically cleaved into two ... See full document
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The anticancer effects of ferulic acid is associated with induction of cell cycle arrest and autophagy in cervical cancer cells
... as P53 and its downstream regulators [19]. P21 and P53 genes as the stimulated markers, are involved in cell cycle and apoptosis ...injured cells [21]. Additionally, P53 protein is a ... See full document
8
Regulation of p53-dependent apoptosis, transcriptional repression, and cell transformation by phosphorylation of the 55-kilodalton E1B protein of human adenovirus type 5.
... both p53-dependent and p53-inde- pendent apoptosis (65, ...the p53-independent process has been shown to require the transactivation of other early viral genes by con- served region 3 ... See full document
Midazolam regulated caspase pathway, endoplasmic reticulum stress, autophagy, and cell cycle to induce apoptosis in MA-10 mouse Leydig tumor cells
... MA-10 cells were treated with midazolam (0, 30, and 150 µM) for 3, 6, 12, and 24 hours ...MA-10 cells were treated with 0 or 150 µM midazolam for 6, 12, and 24 ... See full document
13
Histone Deacetylase Inhibitor Trichostatin a Promotes the Apoptosis of Osteosarcoma Cells through p53 Signaling Pathway Activation
... (MMP-9). Collectively, there is still controversial that whether HDAC inhibition could repress the invasion of osteosarcoma cells[70]. Moreover, in some cases, SIRT1 has been used as a molecular marker in ... See full document
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