[PDF] Top 20 Diseño de un sistema de costos para la empresa del rubro de alimentos
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A miR-200c/141-BMI1 autoregulatory loop regulates oncogenic activity of BMI1 in cancer cells
... The miR-200c/141 locus on chromosome 12 encodes miR-200c and miR-141, two members of the miR-200 family, which have been shown to function as tumor suppressive ... See full document
120
A Polycomb-mir200 loop regulates clinical outcome in bladder cancer
... aberrant miR-200 repression has been associated with transcriptional repression by EZH2 ...of miR-200 family and those genes controlled by PRC2 ...of BMI1 caused a moderate increase of EZH2 ... See full document
134
Original Article Differential expression of miR-200c in breast cancer stem cells
... including miR- 21, miR-10b and miR-200c between breast cancer cells and normal tissues ...[14-16]. Cancer cells are proposed to regulate pathology and cell ... See full document
41
miR-200c inhibits breast cancer proliferation by targeting KRAS
... [36]. miR-200c miRCURYTM LNA custom detection probes (Exiqon, Vedbaek, Denmark) were used for ...of miR-200c staining was scored by 0–4, according to the standards of 0–1 (no staining), 1–2 ... See full document
136
The Dynamic Partnership of Polycomb and Trithorax in Brain Development and Diseases
... stem cells (ESCs) [28], suggesting that YY1 does not recruit PRC2 to DNA in ...human cells [29–31]. PRE-kr regulates the MafB/Kreisler gene’s spatial expression during hindbrain formation in mouse ... See full document
6
Reduced miR-200b and miR-200c expression contributes to abnormal hepatic lipid accumulation by stimulating JUN expression and activating the transcription of srebp1
... that miR-200s participated in IL-6-induced hepatic insulin ...of miR-200s in hepatic lipid accumulation has not been ...that miR-200b and miR-200c were reduced in the steatotic livers ... See full document
125
Original Article Over-expression of BMI1 is associated with favorable prognosis in cervical cancer
... of BMI1. Briefly, BMI1 nuclei were stained, the intensity of which was categorized as 0 (no staining), 1+ (weak), 2+ (moderate) or 3+ (str- ...ong). BMI1 were interpreted according to wei- ghted ... See full document
108
Original Article Silencing Bmi1 inhibits the proliferation and invasiveness in CD133 cancer stem cells of Hep-2 cells
... breast cancer [27]. Bmi1 is critical to invasive potential and contributes to the maintenance and self-renewal of CSCs [9, 28, ...that Bmi1 overexpression drives stem-like properties associated with ... See full document
187
Original Article Exosomal miR-200 family as serum biomarkers for early detection and prognostic prediction of cholangiocarcinoma
... the miR-200 family, as serum biomarkers for the diagnosis of ...them, miR-200c-3p displayed excellent diagnostic value with the AUC of > ...exosomal miR-200c-3p by itself alone or ... See full document
46
MK3 controls Polycomb target gene expression via negative feedback on ERK
... [12]. Cells were fixed for 10 minutes in 1% formaldehyde/phosphate buf- fered saline (PBS) and stopped by 5 minutes incubation in glycine (final concentration: ...Fixed cells were washed twice with PBS and ... See full document
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MiR-200c sensitizes Olaparib-resistant ovarian cancer cells by targeting Neuropilin 1
... of cancer-related death in women ...ovarian cancer patients har- bor a germline mutation in genes encoding BRCA1 and BRCA2 proteins, which are involved in the process of homologous recombination (HR) that ... See full document
13
Original Article MiR-218 suppresses osteosarcoma proliferation by down-regulating BMI1
... The mortality rates of children and adolescents with osteosarcoma are still very high, but early detection and timely treatment has increased the survival rate. Moreover, effective chemo- therapy regimens have ... See full document
40
Bmi1 regulates murine intestinal stem cell proliferation and self renewal downstream of Notch
... crypt cells of WT mice ...of Bmi1 expression in these cells (data not shown) that was not recovered by the constitutive activation of the β -catenin pathway ...maintain Bmi1 expression even in ... See full document
11
BTF3 sustains cancer stem-like phenotype of prostate cancer via stabilization of BMI1
... of cancer cells to grow or to metastasize has been linked to the presence of CSCs ...PCa cells to proliferate and invade, we investigated the role of BTF3 on tumor growth using a xenograft ...PC3 ... See full document
19
Expression of seven stem-cell-associated markers in human airway biopsy specimens obtained via fiberoptic bronchoscopy
... breast cancer [20], gastric adenocarcinomas [21], colorectal cancer [22], gli- omas [23] and ovarian serous cystadenocarcinomas ...lung cancer patients was signifi- cantly higher compared to that in ... See full document
17
LncRNA XIST/miR-200c regulates the stemness properties and tumourigenicity of human bladder cancer stem cell-like cells
... cancers. miR-200c functions as a tumour suppressor that impacts the growth of bladder cancer cells and the epithelial-to-mesenchymal transition ...promotes cancer progression and might ... See full document
15
Dysregulated miRNA Associated with Transcription Factors of Insulin Gene Expression in Chronic Pancreatitis
... Although comprehensive search was conducted for target gene prediction, networks were generated restricting the analysis to target genes that are asso- ciated with oxidative stress, cytokine signaling, Inflammation and ... See full document
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Clinical Correlation of miR-200c/141 Cluster DNA Methylation and miR-141 Expression with the Clinicopathological Features of Colorectal Primary Lesions/Tumors
... Statistics were analyzed with IBM SPSS statistical software, version 19 (SPSS Inc., Chicago, IL). Quantitative data was described as the mean ± standard deviation (SD). Correlations between clinicopathological factors ... See full document
24
Juxtaposed Polycomb complexes co regulate vertebral identity
... The aggregate findings are depicted in a dynamic model of PcG complex assembly in mouse Hox gene clusters (Fig. 7). During the early maintenance phase of axial Hox gene repression, presumably between E9 and 10 (Yu et ... See full document
17
Polycomb group gene BMI1 controls invasion of medulloblastoma cells and inhibits BMP-regulated cell adhesion
... between BMI1 and TGFβ-regulated cell adhesion molecules identified in murine GCPs and MB cell lines we examined gene expression patterns across large cohorts of human pri- mary MB samples (n = ...of BMI1, ... See full document
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