[PDF] Top 20 Effects of the economic crisis on Spanish libraries
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DNA Methylation of the LY86 Gene is Associated With Obesity, Insulin Resistance, and Inflammation
... The LY86 gene CpG site is within the top 500 CpG sites showing differential methylation among leukocyte subtypes (Supplementary Figure 1; Koestler et ...with obesity status (p = ...the ... See full document
107
“Role of Probiotics in Type 2 Diabetes Mellitus” by Nibedita Priyadarsini, Tapaswini Mishra, Manasi Behera, Dipti Mohapatra, Priyambada Panda, India.
... diet associated with exaggerated post-prandial spikes in glucose and lipids generate excess free radicals that can trigger a biochemical cascade resulting in chronic, low grade systemic inflammation 23 ... See full document
22
Chemokine (C-C motif) Ligand 2 is a potential biomarker of inflammation & physical fitness in obese children: a cross-sectional study
... similar insulin sensitivity, while Roth et ...their insulin levels and HOMA-IR based on their ...out insulin resistance as a factor associated with obesity- related ... See full document
53
Inflammation is not a contributing factor in the development of insulin resistance in diet induced obesity in rats
... diet-induced obesity and its associated health complications in all animal ...be associated with a straightforward calorie swap of one dietary component for ... See full document
116
Associations of LEP, CRH, ICAM-1, and LINE-1 methylation, measured in saliva, with waist circumference, body mass index, and percent body fat in mid-childhood
... between DNA methylation, measured in saliva samples, and anthropo- metric and body composition measurements (hereafter called “obesity-related measures”) in 431 adolescents between 10 and 15 years of ... See full document
12
Epigenetic regulation of macrophage polarization and inflammation by DNA methylation in obesity
... by DNA methylation is an underlying mechanism mediating obesity-induced ATM phenotypic switch and ...First, obesity results in increased classically activated M1 ATMs and reduced alternatively ... See full document
53
Obesity and the development of type 2 diabetes: the effects of fatty tissue inflammation
... conditions. Obesity is commonly associated with increased production of proinflammatory cytokines, insulin resistance, and changes in body fat ...potentiate insulin resistance ... See full document
26
Vitamins D, C, and E in the prevention of type 2 diabetes mellitus: modulation of inflammation and oxidative stress
... low-grade inflammation resulting from oxidative stress and imbalances in the innate immune system has been associated with obesity, metabolic syndrome, and insulin resistance – critical ... See full document
15
Skeletal muscle inflammation and insulin resistance in obesity
... that obesity is associated with increased inflammation in SM, which is mainly manifested by enhanced immune cell infiltration in IMAT/PMAT and also includes increased myocyte ...are associated ... See full document
6
Obesity and insulin resistance
... cause insulin resistance? TNF-α signaling impairs insulin signaling, in part through serine phosphorylation of IRS-1 (32, 33), and can reduce GLUT4 gene expression, so a plausible cel- lular ... See full document
45
Precision DNA demethylation ameliorates disease in lupus-prone mice
... enhanced DNA demethylation in either CD4 or CD8 T cells is clinically beneficial in mice with established disease, despite the fact that global demethylation orchestrates the development of ... See full document
15
Pediatric non alcoholic fatty liver disease: old and new concepts on development, progression, metabolic insight and potential treatment targets
... Histopathological pattern and New scoring systems The pattern of the distribution of pediatric NAFLD histo- logical lesions is frequently different from that of adults. Classical histological findings that characterize ... See full document
10
Inflammation and insulin resistance
... link inflammation to the pathogenesis of type 2 diabetes (T2D), but the antihypergly- cemic and antiinflammatory effects of salicylates were not connected to the pathogenesis of insulin resistance ... See full document
24
Independent tissue contributors to obesity-associated insulin resistance
... on insulin resistance is controversial; the increased lipolysis and adipokine dysregulation in SAT is considered to contribute to insulin resistance (2), yet a fat distribution pattern with ... See full document
9
<p>Salivary Amylase Gene Copy Number Is Associated with the Obesity and Inflammatory Markers in Children</p>
... of obesity has increased three times compared to 1975 and projected to persist in the ...though obesity is known as an imbalance between energy expenditure and food intake, there are several genetic and ... See full document
16
Increased abundance of the receptor type protein tyrosine phosphatase LAR accounts for the elevated insulin receptor dephosphorylating activity in adipose tissue of obese human subjects
... the insulin receptor and other proteins in the insulin signalling ...is associated with adipose tissue insulin resistance in human obesity we measured PTPase enzyme activity ... See full document
102
Biochemical Study of the Effects of Insulin Resistance on Sex Hormones in Men and Women Type-2 Diabetic Patients / Meisan-Iraq
... The obesity probably act as a diabetogenic factor, through increasing resistance to the action of insulin, in those genetically predisposed to develop type 2 diabetes; insulin ... See full document
27
DNA methylation profile of the DKK2 gene as a biomarker in patients with colorectal cancer
... Of the four vertebrates Dickkopf-related (DKK) proteins (DKK1, DKK2, DKK3, and DKK4), DKK1 and DKK2 are secreted proteins with two cysteine-rich domains separated by a linker region. During vertebrate development, the ... See full document
21
DNA methylation links genetics, fetal environment, and an unhealthy lifestyle to the development of type 2 diabetes
... includes DNA methylation, histone modifications, and non-coding RNA. DNA methylation is the most studied epigenetic mark so far and occurs mainly at the fifth position of the cytosine ring in ... See full document
6
In obesity and weight loss, all roads lead to the mighty macrophage
... ATM functions during weight loss While ATMs in obesity contribute to adi- pose tissue inflammation and insulin resistance, the functions of ATMs during weight loss are not known. To address ... See full document
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