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... Mixed 1ml Ortho Phosphoric acid in 1litre water, filtered through 0.45µm nylon membrane filter. Mobile phase: A mixture of Acetonitrile and 0.1%OPA in the ratio of 25:75%v/v was sonicated to degas and filtered through ... See full document

... Every country has legislation on bulk drugs and their pharmaceutical formulations that sets standards and obligatory quality indices for them. These regulations are presented in separate articles relating to individual ... See full document

... reference and test solutions were carried out in 1 cm matched quartz cell over the range of 200- 400 nm. Methanol and distilled water are used as solvent. Results were shown that the first method is the application of ... See full document

... new RP-HPLC method has been developed for quantitative analysis of cinacalcet in tablet ...formulation. Validation study result of this developed method revels that the developed method ... See full document

... rates for the separation of olmesar tan and hydrochlorothiazide with good chromatographic parameters (resolution, symmetry, tailing factor etc.). A C 18 column (250 mm×4.6 mm i.d., 5µm.) as a stationary phase with ... See full document

... the estimation of sofosbuvir in bulk and tablet dosage ...260nm. Quantitative linearity was obeyed in the concentration range of 100 to 600 µg/ml, the regression equations of concentration ... See full document

... indicating HPLC analytical method has been developed and validated for the Quantitative analysis of Sofosbuvir and Ledipasvir in combined tablet dosage ...in tablet dosage forms ... See full document

... Sensitivity: The Limit of Detection (LOD) was determined as lowest concentration giving response and Limit of Quantification (LOQ) was determined as the lowest concentration analyzed with accuracy method were determined ... See full document

... Pharmacokinetics: Chlortalidone is slowly absorbed from the gastrointestinal tract after oral ingestion. It has a long half-life and therefore a prolonged diuretic action, which results in continued diuretic effects ... See full document

... indicating RP-HPLC method has been developed for estimation of Epalrestat and Pregabalin in bulk and tablet dosage ...accurate RP-HPLC method for the analysis of ... See full document

... proposed RP-HPLC method was validated as per International Conference on Harmonization (ICH) guidelines, and found to be applicable for routine quality control analysis for the simultaneous ... See full document

... mg Hydrochlorothiazide and 50 mg Losartan potassium, were weighed and average weight ...Atenolol, Hydrochlorothiazide& Losartan of the above stock solution into a 10ml volumetric flask and dilute up to ... See full document

... Different solvents such as distilled water, methanol, ethanol, toluene, acetic acid, isopropyl alcohol, N-butanol carbon tetrachloride, benzene, hexane, ethyl alcohol, acetonitrile, chloroform, diethyl ether and acetone ... See full document

... Naratriptan is Antimigrainic agent. It is chemically, N-methyl-2-[3-(1-methylpiperidin-4-yl)-1H- indol-5-yl]ethane-1- Sulfonamide. Its Molecular Formula is C17H25N3O2S (Anonymous 1). This paper now describes an ... See full document

... Intraday and Interday Precision of the method was also performed by preparing six (n=6) replicate samples and analyzed on same day for intraday and on different days for interday precision. The peaks were recorded and % ... See full document

... Combination of Epalrestat and Pregabalin tablets (PREALDONIL 150MG TABLET), Distilled water, Acetonitrile, Phosphate buffer, Methanol, Potassium dihydrogen ortho phosphate buffer, Ortho-phosphoric acid. All the ... See full document

... Initially reverse phase liquid chromatography separation was tried to develop using various ratios of Methanol: Water, Acetonitrile and Water as mobile phases, in which both the drugs did not responded properly, and the ... See full document

... indicating RP-HPLC method was developed and validated for the simultaneous estimation of Metformin and Glipizide in combined pharmaceutical dosage ...routine quantitative analysis of ... See full document

... Specificity of the method was determined by comparing the retention times of MET and STG of standard solution with the retention times of MET and STG of sample solutions. Good correlation was obtained between the ... See full document

... utilized in HPLC UV detector for estimating the Nevirapine. While scanning the Nevirapine solution we observed the maxima at 246nm. The UV spectrum has been recorded on LABINDIA make UV – Vis spectrophotometer ... See full document