[PDF] Top 20 La infancia desde las apuestas formativas en educación y la política pública
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<p>Anabolics in the management of glucocorticoid-induced osteoporosis: an evidence-based review of long-term safety, efficacy and place in therapy</p>
... increase in osteoclastogenesis that leads to an increase in bone resorption. This effect is mediated by an upregulation of receptor activator of nuclear factor kappa- Β ligand (RANKL) and macrophage colony-stimulating ... See full document
7
An evidence-based review of natalizumab therapy in the management of Crohn’s disease
... entitled Efficacy of Natalizumab as Active Crohn’s Therapy (ENACT-1) and the second a maintenance trial entitled Evaluation of Natalizumab as Continuous Therapy ...49%, P = ...30%, P = ... See full document
8
Micafungin: an evidence-based review of its place in therapy
... intravenous therapy was comparable among the groups and numerically better, although not statistically better, for micafungin at 100 mg intravenously ...intravenous therapy. The primary efficacy ... See full document
11
Long-term safety, efficacy, and patient acceptability of teriparatide in the management of glucocorticoid-induced osteoporosis
... of glucocorticoid use is increased risk of ...of glucocorticoid therapy. Nevertheless, 30%–50% of patients on long-term glucocorticoid therapy sustain a ...self-injectable ... See full document
17
Rasburicase in the management of tumor lysis: an evidence-based review of its place in therapy
... (clear evidence) which prob- ably improves outcomes in patients at high risk for TLS (clear evidence that it reduces uric acid, substantial evidence of reduction in LTLS/CLTS and AKI/need for RRT, ... See full document
12
Long-term treatment of osteoporosis: safety and efficacy appraisal of denosumab
... right therapy for each osteoporotic ...rently based on the need to reduce fracture ...and based on the properties of denosumab and its mode of action, it can be considered in: patients at high risk ... See full document
11
<p>Stereoelectroencephalography in epilepsy, cognitive neurophysiology, and psychiatric disease: safety, efficacy, and place in therapy</p>
... and safety of deep brain stimulation, a relatively reversible procedure, for movement disorders and the persistence of medication refractory psy- chiatric diseases, there has been renewed interest in using ... See full document
5
Long-term safety and efficacy of raloxifene in the prevention and treatment of postmenopausal osteoporosis: an update
... and osteoporosis. Osteoporosis is a chronic disease requiring long-term therapy and it is important to evaluate the effi cacy and safety of treatments over several years, as the ... See full document
8
Long-term safety and efficacy of budesonide in the treatment of ulcerative colitis
... Current UC treatments for an acute flare include aminosali- cylates, glucocorticoids, and biological therapies. First line therapy for mild to moderately active UC is mesalazine; corticosteroids and anti-TNF- α ... See full document
42
Long-term safety and efficacy of dasatinib in the treatment of chronic-phase chronic myeloid leukemia patients resistant or intolerant to imatinib
... a F317L mutation was first detected while a CML-CP patient was undergoing treatment with dasatinib. Treatment with dasatinib was continued, and a sustained MMR was achieved while the F317L mutation was not detectable in ... See full document
29
Long-term efficacy and safety of ramosetron in the treatment of diarrhea-predominant irritable bowel syndrome
... and long-term efficacy for overall improvement of IBS symptoms was also ...for long-term treatment with ...the long-term efficacy and safety of ramosetron ... See full document
29
EVALUATION OF ADVERSE EFFECTS AND UTILIZATION OF GLUCOCORTICOIDS IN A TERITARY CARE HOSPITAL
... topical glucocorticoid preparation are most commonly prescribed agents in the out-patient dermatology department since it was ...possible glucocorticoid to treat the dermatological condition and to be also ... See full document
5
Long-term safety, efficacy, and tolerability of imidafenacin in the treatment of overactive bladder: a review of the Japanese literature
... better safety profile than propiverine. Several short-term clinical studies have demonstrated that imidafenacin also improves sleep disorders, nocturia, and nocturia-related quality of ...addon ... See full document
6
<p>Once-monthly galcanezumab for the prevention of migraine in adults: an evidence-based descriptive review and potential place in therapy</p>
... tial place in therapy may be considered for diverse migraine endophenotypes, hopefully identifiable through a reliable biomarker – that, however, still has to be ...both efficacy and safety, ... See full document
10
<p>Re-Evaluating the Use of IFN-β and Relapsing Multiple Sclerosis: Safety, Efficacy and Place in Therapy</p>
... systemic review by Melendez-Torres et al con fi rms the bene fi ts of IFN β therapy demonstrating comparative effec- tiveness on relapses and disability, and adherence rates when compared to glatiramer ... See full document
5
Management of glucocorticoid-induced osteoporosis: prevalence, and emerging treatment options
... oral risedronate, 5 mg, were compared in a 1-year random- ized, double-blind, double-dummy study of patients with less than 3 months’ exposure of glucocorticoids and those in treatment for longer than 3 months. After 12 ... See full document
10
<p>Enasidenib in the treatment of relapsed/refractory acute myeloid leukemia: an evidence-based review of its place in therapy</p>
... Preclinical data showed that mutations in IDH cause dependence on the anti-apoptotic gene BCL-2 in leukemic cells, and the BCL-2 inhibitor, venetoclax, demonstrated signi fi cant preclinical activity in mIDH disease. 56 ... See full document
14
Long-term safety and efficacy of tobramycin in the management of cystic fibrosis
... Abstract: Cystic fibrosis (CF) is a fatal inherited disease caused by mutations in the CF transmembrane conductance regulator (CFTR) gene whose mortality is conditioned by a pro- gressive decline in lung function. ... See full document
6
Long term efficacy and safety of etanercept in the treatment of psoriasis and psoriatic arthritis
... The evidence of their impact in other organs has led to a major change in the definition of these diseases, once considered only limited to skin and/or ...their efficacy and ...of safety data has ... See full document
22
<p>Denosumab in the treatment of glucocorticoid-induced osteoporosis: a systematic review and meta-analysis</p>
... Dore et al 20 reported a subgroup analysis of a multi- center, double-blind, placebo-controlled, randomized trial comparing the effects of denosumab and placebo on struc- tural damage in rheumatoid arthritis patients. 20 ... See full document
9
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