[PDF] Top 20 Influencia del proyecto Espince en el desarrollo de la cultura en el Municipio de Moa
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Wnt3a: functions and implications in cancer
... [53]. Wnt3a decreases proliferation rate and induces myogenic differentiation in alveolar rhabdomyosarcoma cells ...hand, Wnt3a antagonizes the inhibition of the self-renewal of liver cancer stem ... See full document
255
Clinical implications of antitelomeric drugs with respect to the nontelomeric functions of telomerase in cancer
... In spite of their promise, more detailed analyses are required to confirm the safety of anticancer drugs targeting telomeres and telomerase. Prior to clinical trials, the poten- tial risks of the treatments should be ... See full document
12
Immunoregulatory functions and the therapeutic implications of GARP-TGF-β in inflammation and cancer
... GARP enhances the activation of latent TGF-β released by platelets [24]. Serum active TGF-β was drastically re- duced in these mice, and interestingly, the similar pheno- type was not observed in mice with ... See full document
20
New insights in the composition of extracellular vesicles from pancreatic cancer cells: implications for biomarkers and functions
... The protein cargo of EVs and secretomes from pancre- atic cancer cells suggests functional activities previously shown for other cellular systems. In some publications using rat models, EVs are suggested to ... See full document
561
Circular RNAs in cancer: new insights into functions and implications in ovarian cancer
... Another group of scientists had reported a novel cir- cRNA named circITGA7 which was markedly downreg- ulated in colorectal cancer CRC) tissue and cell lines. They also found that the linear form of ITGA7 has been ... See full document
23
Acetylation and deacetylation of Cdc25A constitutes a novel mechanism for modulating Cdc25A functions with implications for cancer
... This study provides new and revealing results that support the importance of Cdc25A acetylation in response to genotoxic stress and in cancer. We have uncovered a novel regulatory layer for modulating Cdc25A ... See full document
148
Cancer as a metaphor
... for cancer, but none have investigated her claims about the uses and implications of cancer as a metaphor ...the cancer of corruption), and her prediction that medical advances would make this ... See full document
78
Multiple roles and therapeutic implications of Akt signaling in cancer
... Figure 2 Biological functions of Akt signaling. Most of the cellular responses controlled by Akt are related to cancer. Once active, Akt regulates the activity of other intracellular signaling proteins that ... See full document
6
The chromatin-remodeling enzyme BRG1 promotes colon cancer progression via positive regulation of WNT3A
... In cancer, experiments in vitro have revealed that BRG1 accelerates cancer cell proliferation in glioma and in breast cancer [16, ...inhibits cancer aggressiveness, acting as tumor suppressor ... See full document
81
Increased glutamine catabolism mediates bone anabolism in response to WNT signaling
... The present work provides insights into the mechanism through which WNT signaling stimulates bone formation. Our previous studies have shown that WNT functions through mul- tiple downstream effectors, including ... See full document
197
Cancer cell dormancy: mechanisms and implications of cancer recurrence and metastasis
... and cancer cell ...augment cancer cell adhesion and migration in melanoma; therefore, the function of LTBP-2 is related to specific tumor types and ... See full document
13
Long noncoding RNAs in gastric cancer: functions and clinical applications
... Therefore, the expression levels and functions of lncRNAs differ during the different stages of GC. In particular, in the early stages of GC, when tumor sizes are too small for accurate detection using imaging ... See full document
9
<p>The Biogenesis, Functions, and Roles of circRNAs in Bladder Cancer</p>
... and functions of circRNAs are still ...whose functions are unknown, the function of only a few circRNAs has been veri fi ...BCa cancer tissues compared to normal tissues in the same diseased bladder ... See full document
7
A systematic review of the prevalence of comorbid cancer and dementia and its implications for cancer related care
... dementia, cancer and ...of cancer-dementia and d) original articles that assessed prevalence and/or cancer-related experiences including screening, cancer treatment and ...varied ... See full document
10
Pleiotropic functions of miR107 in cancer networks
... controlling cancer-onset, growth, and progression ...tumor-suppressor functions in different human tumors. The pleiotropic functions of miR107 in various cancers are achieved via its targeting ... See full document
10
Functions and Implications of Circular RNAs in Antiviral Immunity
... In addition to mature mRNAs, splicing of pol II transcripts generates nu- merous other RNAs including circular RNAs (circRNAs). circRNAs are a group of transcripts generated by non-sequential back splicing or forward ... See full document
90
Overcoming Diminished Motivation
... surveys. Cancer registries, while a great source of data on new cases of cancer, may not include sexual orientation in their ...National Cancer Institute’s Surveillance, ... See full document
7
Wnt and FGF signals interact to coordinate growth with cell fate specification during limb development
... to Wnt3a, they lost their chondrogenic potency following prolonged (>42 hours) exposure (see ...of Wnt3a and monitored the expression of a panel of differentiated tissue markers (Table ... See full document
17
Niclosamide suppresses hepatoma cell proliferation via the Wnt pathway
... Huh-6 cells were trypsinized, harvested, and spread onto 96-well flat-bottom plates (Asahi Techno Glass, Tokyo, Japan) at a density of 1,000 cells per well, and then incu- bated for 24 hours in Dulbecco’s Modified ... See full document
9
Emerging Implications of Nanotechnology on Cancer Diagnostics and Therapeutics
... breast cancer [9, 10] and other nonhematologic malignancies [11, ...important implications for management of the cancer patient in the near ...in cancer diagnostics and ... See full document
16
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