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Proteome profiling of low grade serous ovarian cancer
... of ovarian cancer (68%), more than 95% of serous who are diag- nosed with poor survival chance and metastatic condi- tion [6 – ...with low grade ovarian cancer have a ... See full document
5
Markers of MEK inhibitor resistance in low-grade serous ovarian cancer: EGFR is a potential therapeutic target
... Activating mutations affecting the MAPK pathway (RAS/ RAF/MEK/ERK) are frequently found in cancer. MAPK pathway inhibitors, such as MEK inhibitors, were devel- oped as targeted therapeutics to potentially treat ... See full document
43
Aurora Kinase A expression predicts platinum-resistance and adverse outcome in high-grade serous ovarian carcinoma patients
... and it has been identified as a low penetrance tumor- susceptibility-gene in human cancer [21]. Moreover, spe- cific AURKA polymorphisms have been associated with carcinogenesis [22–28], while its ... See full document
9
Original Article The clinical study of secondary cytoreductive surgery in the treatment of low grade serous ovarian cancer
... epithelial ovarian cancer, mainly focused on the treatment scheme of high-grade serous ovarian ...high- grade serous ovarian cancers require chemo- therapy or ... See full document
33
Expression of hypothalamic-pituitary-gonadal axis-related hormone receptors in low-grade serous ovarian cancer (LGSC)
... Low-grade serous ovarian cancer (LGSC) represents less than 10% of serous ovarian cancers and is less sensi- tive to conventional platinum-based chemotherapy com- pared ... See full document
12
Original Article Overexpression of β-catenin and cyclinD1 predicts a poor prognosis in ovarian serous carcinomas
... with serous cancer of ovary were obtained from Jinling Hospital, Nanjing, China, between the years 1997 and ...histological grade, and ...of ovarian serous car- ...of ovarian ... See full document
15
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... of ovarian cancer has been developed based on a long history of pathological and molecular genetic ...divides ovarian cancer as having designated type I or type II ...involves ovarian ... See full document
16
A survival analysis comparing women with ovarian low-grade serous carcinoma to those with high-grade histology
... Abstract: Ovarian low-grade serous carcinoma (LGSC) and high-grade serous carcinoma have distinct molecular profiles, clinical behaviors, and treatment ...with ... See full document
10
Mechanisms underlying chemotherapy-induced vascular proliferation in ovarian cancer
... Classification, ovarian neoplasms are categorized by the most probable cell of origin, and the site of origin (ovary ...of ovarian cancers are surface epithelial tumours, but ovarian cancer is ... See full document
129
Ovarian low and high grade serous carcinomas: hidden divergent features in the tumor microenvironment
... epithelial ovarian cancer ...the cancer mass rises and an intratumoral vascular network forms, monocyte-derived TAMs turn out to be the main source of TAMs ...in ovarian cancer ... See full document
23
<p>WTAP is a prognostic marker of high-grade serous ovarian cancer and regulates the progression of ovarian cancer cells</p>
... colorectal cancer, the level of WTAP-WT1 complex decreased when WTAP suffered from degradation, causing free WT1 released, 9 causing tumor ...with low-WT1 and high-WTAP expression were subjected to the ... See full document
73
Circulating tumor cells as a new and additional approach to follow-up patients with serous low-grade ovarian adenocarcinoma – a case report and review of the literature
... The controversial findings of these studies can be ex- plained by the diversity of the enrolled population, sample size, different times of blood collection and diverse tech- niques used to isolate CTCs. Most these ... See full document
45
Advances in Tumor Screening, Imaging, and Avatar Technologies for High-Grade Serous Ovarian Cancer
... diagnose ovarian cancer, mainly for late stage cases, and to predict the chance of tumor recurrence ...identify cancer risk based on rising trends in individual CA-125 levels ...vCAM cancer ... See full document
113
Notch signaling in serous ovarian cancer
... in serous ovarian cancer While Notch signaling has been linked extensively to tumor angiogenesis [106-108] in many malignancies, few studies have described a similar role of the pathway in ... See full document
26
Original Article Different expression of S100A11 in normal ovarian epithelium, serous benign/borderline tumor, and low-grade serous ovarian carcinoma
... breast cancer metastasis [27] and related to a more aggressive phenotype in numerous can- cers ...colorectal cancer enhances tumor growth in vivo ... See full document
40
Molecular profiling of low grade serous ovarian tumours identifies novel candidate driver genes
... prostate cancer cells USP9X has been found to deubiquitinate and stabilise ERG [32], while increasing expression of USP9X was found to correlate with higher grade and poorer outcome in oesophageal squamous ... See full document
62
Epigenetic remodeling regulates transcriptional changes between ovarian cancer and benign precursors
... of ovarian cancer cells but not benign fallopian tube secretory ...The Cancer Genome Atlas (TCGA) (18–21). Three high-grade serous cancer lines, for which we have previously ... See full document
7
Genomic scars as biomarkers of homologous recombination deficiency and drug response in breast and ovarian cancers
... Genomic scars as reporters of homologous recombination deficiency and drug response A genomic scar can be defined as a genomic aberration with a known origin. Recent attempts at developing an assay that acknowledges the ... See full document
580
Genomics and molecular mechanisms of high grade serous ovarian cancer: the 12th Biennial Rivkin Center Ovarian Cancer Research Symposium
... high grade serous ovarian cancer exhibits a high degree of somatic copy number ...high grade serous ovarian ...high grade serous ovarian cancer ... See full document
6
Case Report Low-grade endometrioid carcinoma of the ovary associated with undifferentiated carcinoma: case report and review of the literature
... primary ovarian malignancies [1]. The association of low-grade endometrioid carcinoma (LGEC) with UC was first reported in endometrium carcinoma, termed with dedifferentiated carcinoma (DC) by Sliva ... See full document
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