[PDF] Top 20 Lactancia materna como factor protector de la obesidad infantil y en edades futuras
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Neoadjuvant oxaliplatin and capecitabine combined with bevacizumab plus radiotherapy for locally advanced rectal cancer: results of a single-institute phase II study
... previous single-arm studies, did not improve surgical outcomes such as pCR rate, but increased toxicity in the Italian STAR-01 study [38] as well as the US NSABP R-04 trial ...of oxaliplatin to ... See full document
20
The high pCR rate of sandwich neoadjuvant treatment in locally advanced rectal cancer may translate into a better long-term survival benefit: 5-year outcome of a Phase II clinical trial
... a Phase II clinical trial, we reported the effectiveness and safety of a sandwich neoadjuvant treatment based on a modified oxaliplatin plus capecitabine (XELOX) regimen for ... See full document
28
Prospective clinical study of capecitabine plus oxaliplatin concurrent chemoradiotherapy after radical resection of rectal cancer
... type II/III rectal cancer (type I ...and radiotherapy, standard treatment of total mesorectal excision (TME) and neoadjuvant chemoradiation significantly improved the treatment of local ... See full document
127
Critical role of bevacizumab scheduling in combination with pre- surgical chemo-radiotherapy in MRI-defined high-risk locally advanced rectal cancer: results of the braNCh trial
... of locally advanced rectal cancer ...promising results from a phase-2 trial based on an original intensified preoperative chemotherapy (CT) regimen including oxaliplatin ... See full document
10
Targeting cancers in the gastrointestinal tract: role of capecitabine
... for intravenous (iv) fl uids and antibiotics if accompanied by neutropenia. About half the patients treated will also develop a degree of HFS which may be helped by the use of pyridoxine (vitamin B6). Many patients ... See full document
19
Phase II Clinical Trial of Concurrent Neoadjuvant Chemotherapy With Radiotherapy in Locally Advanced Breast Cancer
... (see study protocol, Appendix III), and in all but one of these cases, patients were clinically resolved by the time surgery was done 5 weeks ...bilateral locally advanced breast ... See full document
162
Prognostic value of neutrophil-to-lymphocyte ratio in advanced oesophago-gastric cancer: exploratory analysis of the REAL-2 trial
... current study, is the lack of con- sensus regarding the most appropriate cut-off for evaluation of the ...our study, we had pre-speci fi ed at the time of formulating the statistical plan for this analysis ... See full document
38
Lapatinib in combination with capecitabine in the management of ErbB2-positive (HER2-positive) advanced breast cancer
... this study were to evaluate correlations between biomarker expression and clinical endpoints (TTP/progression-free survival [PFS]) and to characterize the biomarker predictors of benefi t from ...the ... See full document
20
Outcomes of neoadjuvant chemoradiotherapy in Japanese locally advanced rectal carcinoma patients
... with rectal cancer after NACRT ...in rectal cancer [20] were reported to be predictors of recur- rence after ...Further study will be necessary to clarify the predictive factors ... See full document
138
<p>Concomitant dose escalation with image–guided Tomotherapy in locally advanced mid–low rectal cancer: a single-center study</p>
... The primary end point of this study was the pCR rate. The secondary end points, including resection rate, sphincter- preserving rate, downstaging rate, acute and postoperative complications, pattern of failure, ... See full document
16
Neoadjuvant Chemoradiation in Locally Advanced Rectal Cancer
... with radiotherapy gives an added advantage in sterilizing microscopic disease in regions that either cannot be resected or ought to be ...spared. Neoadjuvant chemoradiation has helped down-staging the ... See full document
Evolving role of cetuximab in the treatment of colorectal cancer
... colorectal cancer and gained an established role in the treatment of this ...a single agent in chemorefractory metastatic disease as well as in combination with varying ... See full document
42
Prospective phase II trial of pazopanib plus CapeOX (capecitabine and oxaliplatin) in previously untreated patients with advanced gastric cancer
... for combined sorafenib or bevacizumab with chemotherapy in the same setting, 91% and 84% of patients experienced grade 3 or more toxicities, respectively [25, ...Another study also demonstrated a ... See full document
157
Role of oxaliplatin in the treatment of colorectal cancer
... nal results of the XENOX trial, assessing the effi cacy of xaliproden in reducing the cumulative PSN induced by FOLFOX4 in metastatic CRC ...the oxaliplatin-induced ...further study has been ... See full document
29
Neoadjuvant chemotherapy in locally advanced cancer cervix. A meta-analysis of phase III trials
... Results: Searching the above websites identified 7 phase III trials that fit with the current inclusion criteria. All the 7 trials included treatment arm for NACT. The other arms were either surgery ... See full document
8
Expert consensus on maintenance treatment for metastatic colorectal cancer in China
... alone. Single-agent capecitabine maintenance is the most evidence-based scheme, and it has been fully verified in Chinese patients with ...Oral single-agent capecitabine mainte- nance is more ... See full document
8
Efficacy and Toxicity of Metronomic Capecitabine in Advanced Hepatocellular Carcinoma
... our study is comparable to most of chemotherapy regimens. In advanced HCC the overall response rate to systemic chemotherapy is generally less than 10% ...in advanced HCC. When given as a ... See full document
126
Neoadjuvant bevacizumab and chemoradiotherapy in locally advanced rectal cancer: early outcome and technical impact on toxicity
... previous study using preoperative bevacizumab with FOLFOX and supine box radiotherapy found postopera- tive complications including delayed healing, leak or ab- scess, ischemic colonic reservoir, and ... See full document
58
Capecitabine and Oxaliplatin versus 5 Fluorouracil in the Neoadjuvant Chemoradiation for Patients with Locally Advanced Rectal Carcinoma: A Comparative Study
... and II respectively), but no significant difference between DFS in different response groups of both arms and no significant dif- ferences in DFS of both arms which wasn’t comparable to updated results of ... See full document
103
Comparison of continuous infusional 5-fluorouracil and capecitabine in preoperative chemo radiotherapy for locally advanced rectal cancer: experience from a tertiary cancer centre from Southern India
... administration, capecitabine approximates continuous infusions of ...colorectal cancer. Several studies established that Capecitabine was well tolerated and was non-inferior to Infusional 5FU in ... See full document
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