[PDF] Top 20 Modelos y Teorias Aplicadas Al Trabajo Social
Has 10000 "Modelos y Teorias Aplicadas Al Trabajo Social" found on our website. Below are the top 20 most common "Modelos y Teorias Aplicadas Al Trabajo Social".
Identification of novel therapeutics for complex diseases from genome-wide association data
... Currently available gene discovery platforms can enhance candidate gene identification from GWAS data [9]. Candidate gene prediction tools are designed to find a needle in the genetic haystack. These ... See full document
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Novel therapeutics for coronary artery disease from genome-wide association study data
... GWAS data using the Gentrepid candidate gene prediction tool as the biological knowledgebase, starting with data from a series of four lower statistical thresholds (p ≤ 5 × 10 -7 , p ≤ 10 -5 , p ≤ 10 ... See full document
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A Novel Genome-Wide Association Study Approach Using Genotyping by Exome Sequencing Leads to the Identification of a Primary Open Angle Glaucoma Associated Inversion Disrupting ADAMTS17
... RNAseq data revealed novel exon expression for ADAMTS17 due to cryptic splicing occurring 3 ’ of the exons located immediately upstream of the inversion ...produced from the modified transcript ... See full document
9
Sparse Simultaneous Signal Detection With Applications in Genomics
... GWAS data of two genetically related ...two diseases without considering the directions of the ...the association signal and only detects simultaneous signals existing in the same ...two ... See full document
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Genome Wide Identification of Klebsiella pneumoniae Fitness Genes during Lung Infection
... for novel therapeutics against ...isolate from a patient with pneumonia; NTUH- K2044, an isolate that caused a PLA; NJST258_1, a carbapenem- resistant (KPC) ST258 isolate; and Kp342, a plant ...also ... See full document
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Genome wide association scan for chronic periodontitis implicates novel locus
... mon complex diseases, this study provides a launching pad for future candidate gene and functional studies of periodontal ...these data via online portals will facilitate the utility of this study in ... See full document
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Identification of novel genetic susceptibility loci for Behçet's disease using a genome wide association study
... The association between polymorphisms within KIAA1529 and LOC100129342 with Behçet's disease sug- gests a potential role for these unknown genes in regulating the immune ...These data suggest that an ... See full document
10
A Novel Approach for Identifying Causal Models of Complex Diseases from Family Data
... diabetes data, the main causal factor was the environment, showing a proportion of ...The genome-wide association studies (GWAS) successfully identified loci associated with type II diabetes; ... See full document
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Cross ancestry genome wide association analysis of corneal thickness strengthens link between complex and Mendelian eye diseases
... results from 14 studies comprising 17,803 individuals of European ancestry (see details in Supplementary Table ...28 genome-wide significant CCT loci (P < 5 × 10 −8 ) (Supplementary Table 2 and ... See full document
243
Modeling the cumulative genetic risk for multiple sclerosis from genome-wide association data
... P-value from the type I test indicated that the marker showed an independent effect in addition to the preceding markers that were already placed in the ...P-value from the type III test indicated if the ... See full document
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Genome-wide association studies of cancer: current insights and future perspectives.
... The 8q24.21 region is one of the most intriguing and important loci to emerge from GWAS and is a good example of such regulatory mechanisms. The genomic interval at 128-130 megabases harbours multiple independent ... See full document
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Family based association analysis of alcohol dependence implicates KIAA0040 on Chromosome 1q in multiplex alcohol dependence families
... extending from rs7522166 to ...significant association with alcohol dependence in a GWAS study [15], a study of this region was ...extending from rs12094153 to rs3753555 covering the TNN/KIAA0040 ... See full document
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Mendelian randomization provides support for obesity as a risk factor for meningioma.
... Supplementary Figure S2: Funnel plots showing for each SNP the causal es7mate of the obesity- related trait on meningioma, and the strength of the instrument. Shown are the results for (A) BMI, (B) BMR, (C) body fat ... See full document
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Illuminating the genome wide activity of genome editors for safe and effective therapeutics
... Most currently envisioned clinical genome-editing strategies do not depend on TP53 inhibition or genetic selection of modified cells. In many cases, clinical strat- egies plan to edit large numbers of primary ... See full document
9
Integrating transcriptome wide study and mRNA expression profiles yields novel insights into the biological mechanism of chondropathies
... summary data of chondropathies were ob- tained from the UK Biobank ...extracted from blood samples stored at the UK Biobank facility for ...[14]. Genome-wide genotyping was conducted ... See full document
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Loci nominally associated with autism from genome-wide analysis show enrichment of brain expression quantitative trait loci but not lymphoblastoid cell line expression quantitative trait loci
... Autism spectrum disorder (ASD) is characterized by impairments in three core domains: development of so- cial interaction; language and communication develop- ment; and restricted or circumscribed interests and ... See full document
7
A genome wide linkage and association scan reveals novel loci for autism
... for genome-wide significance, suggesting that there are not many common loci of moderate to large effect size even in a highly heritable disorder like ...replication data in our study identified a ... See full document
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Genetic variants associated with Crohn's disease
... an association between mutations in toll-like receptor (TLR) 4 (rs4986790) and interleukin 10 receptor, alpha subunit (rs22291130) with Mycobacterium avium subspecies paratuberculosis positive CD patients, 9 ... See full document
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Genome-Wide Identification and Expression
... seed-specific GRF genes may play important roles during seed development in sunflower.. 16.[r] ... See full document
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Genome wide identification of enhancer elements
... Fig. 5. GRIP-seq links a distal cis-regulatory element to the onecut TSS. A distal cis-regulatory element that functions as a transcriptional repressor is shown to physically interact with the TSS of onecut. (A) ... See full document
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