[PDF] Top 20 Plan de mejoramiento del área administrativa de la empresa UPS Soluciones Integrales S.A.S.
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Genome-wide analysis of DNA methylation in subjects with type 1 diabetes identifies epigenetic modifications associated with proliferative diabetic retinopathy
... Methods: DNA methylation was analyzed genome-wide in 485,577 sites in blood from cases with PDR (n = 28), controls (n = 30), and in a prospective cohort (n = ...rate analysis was used ... See full document
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Genome-wide DNA methylation analysis for diabetic nephropathy in type 1 diabetes mellitus
... of genome function without mutating the underlying ...of DNA methyla- tion (the addition of a methyl group to the 5th carbon position of cytosine), histone modifications and non- coding RNAs ...of ... See full document
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Diabetic retinopathy: reversibility of epigenetic modifications and new therapeutic targets
... between DNA methylation and DR development; however, differ- ent forms of diabetes may involve various CpG islands to be methylated during the development of ...of type II dia- betes patients ... See full document
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A study to analyze patterns of structural changes in clinically significant diabetic macular edema on Optical coherence tomography.
... 1.5 mm well defined circular area appearing pale pink in colour. It is located about 3 to 4 mm nasal to the fovea. This site of optic disc sees the termination of all the layers of retina except the nerve fibre layer. ... See full document
3
DNA methylation patterns associated with oxidative stress in an ageing population
... of genome-wide DNA methylation, ten markers of reflect- ing different aspects of oxidative stress and the 10 years of follow-up allowing analyses of incident disease end- ... See full document
6
Integrating epigenomics into pharmacogenomic studies
... interpret genome-wide DNA methylation profi les of all human genes in all major tissues (Bradbury 2003; Rakyan et al 2004; Eckhardt et al 2006), no doubt will provide new insights into the ... See full document
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The United Kingdom Diabetic Retinopathy Electronic Medical Record Users Group: Report 3: Baseline Retinopathy and Clinical Features Predict Progression of Diabetic Retinopathy
... of diabetic retinopathy care to their local population and very few patients switch between providers or access care ...national diabetic retinopathy screening program, a nationwide program ... See full document
6
DNA Methylation in Colorectal Cancer: A brief Review
... DNA methylation is a heritable epigenetic mark involved in the covalent transfer of a methyl group to the C-5' position of the cytosine ring of DNA by enzymes called DNA ... See full document
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Epigenome-Wide DNA Methylation Analysis of Monozygotic Twins Discordant for Diurnal Preference
... preference associated DMPs are detailed in Table ...between DNA methylation levels detected us- ing the Infinium microarray and pyrosequencing platforms (Figure 2; Figure ...DMR analysis with ... See full document
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Genome wide analysis of DNA methylation patterns
... test DNA and control DNA, and are hybridized on a single ...the analysis of DNA methylation in organisms other than mammals and ... See full document
6
From forensic epigenetics to forensic epigenomics: broadening DNA investigative intelligence
... trace DNA would be highly informative in charac- terizing an unknown trace donor, and thus useful in guiding ...cause DNA damage and telomere shortening [65], and also epigen- etic changes, which are caused ... See full document
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Choosing preclinical study models of diabetic retinopathy: key problems for consideration
... Experimentally, mice and rats are still the most popular models of DR, not only because of the advantages mentioned above, but also since there have been many standardized protocols of modeling approaches available for ... See full document
9
Alteration of melatonin secretion in patients with type 2 diabetes and proliferative diabetic retinopathy
... with type 2 diabetes and that there was a complex relation- ship between various components of the autonomic nervous system and nighttime melatonin secretion, they did not find a difference in the melatonin ... See full document
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NETs: organ-related epigenetic derangements and potential clinical applications
... multiple epigenetic modifications have been described across the whole spectrum of NETs, and their putative function as tumorigenic drivers has been ...testing epigenetic biomarkers are therefore ... See full document
7
High level dietary cadmium exposure is associated with global DNA hypermethylation in the gastropod hepatopancreas
... [4]. Methylation of the genome, which encompasses the addition of methyl (-CH 3 ) groups to DNA, is a key epigenetic mechanism involved in regulating ... See full document
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Nivolumab in chemotherapy-resistant cervical cancer: report of a vulvitis as a novel immune-related adverse event and molecular analysis of a persistent complete response
... The PD-1/PD-L1 pathway is one of the most widely understood immune mechanisms involved in cancer, including in cervical carcinoma. PD-L1 expression has been reported in 95% of cervical intraepithelial neo- plasms ... See full document
5
Genome-wide brain DNA methylation analysis suggests epigenetic reprogramming in Parkinson disease
... neurofibrillary tangle stage ≤IV. Neuropathologic evaluations were performed in every case confirming Lewy body (LB) PD, and followed the filtering criteria of Beecham et al., 15 for in- clusion into the study. Staging was ... See full document
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Increased DNA methylation of the SLC30A8 gene promoter is associated with type 2 diabetes in a Malay population
... Genome-wide association studies (GWASs) have iden- tified a number of susceptibility variants for type 2 dia- betes (T2D). The common alleles of single nucleotide polymorphisms (SNPs), ... See full document
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Genome wide association studies for diabetic macular edema and proliferative diabetic retinopathy
... treated type 2 diabetes for at least 5-years were recruited and underwent a thorough ophthalmological examin- ...current analysis although some patients with DME had NPDR ... See full document
99
Epigenetic Inheritance of 5-AZA-2'-Deoxycytidine (5-AZA-CdR) Induced Alterations
... 94 Females were allowed to deliver. At 21 days of age, pups were weaned and body weights were recorded. Males and females were separated then housed four per cage. At 3 months of age, male and female (10 per group) ... See full document
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