[PDF] Top 20 Portadores nasales de Staphylococcus aureus en personal que labora en un Hospital de Santander
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Monitoring disease activity in multiple sclerosis using serum neurofilament light protein
... ease activity, along with the number of patients with RRMS with elevated NFL concentrations in serum and in CSF, was used to calculate sensitivity and ...inflammatory activity. Patients with RRMS ... See full document
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Urinary neopterin: An inflammatory marker of disease activity in multiple sclerosis.
... and/or serum of patients with ...of disease activity but have not proved useful as surrogate markers of disease ...the disease process - an approach which has proved partially ... See full document
131
New developments and future opportunities in biomarkers for amyotrophic lateral sclerosis
... a light (NfL), a medium (NfM) and a heavy (NfH) ...with serum levels, which were found to be strong, independent predictors of survival ...phorylated neurofilament heavy chain and complement C3 ... See full document
5
Fingolimod and CSF neurofilament light chain levels in relapsing-remitting multiple sclerosis
... placebo-controlled study setting that immunomodu- latory therapies can impact on CSF NfL levels. Taken together, the role of CSF NfL quantification as a measure of neuroaxonal damage is corroborated by the observed ... See full document
12
Neurofilament levels, disease activity and brain volume during follow-up in multiple sclerosis
... Forty-one patients with CIS or RRMS were consecu- tively enrolled in a prospective longitudinal cohort study of CIS and newly diagnosed MS at the Department of Neurology, University Hospital of Linköping, Sweden. All ... See full document
8
Neurofilament light chain as a biological marker for multiple sclerosis: a meta-analysis study
... The general characteristics of studies and participants included in the present meta-analysis and meta-regression are shown in Table 1. Thirteen groups were pooled, which comprises of 2,651 participants, including 795 ... See full document
15
Prognostic value of serum neurofilaments in patients with clinically isolated syndromes
... Multiple sclerosis (MS) is a disabling disease of young adults characterized by immune-mediated focal areas of de- myelination disseminated in time and space in the ...the disease 2 ; thus ... See full document
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Serum neurofilament light levels correlate with severity measures and neurodegeneration markers in autosomal dominant Alzheimer’s disease
... studied serum NfL with the same methodology in 48 individuals from a different ADAD cohort ...ours, serum NfL correlated with EYO and cognitive measures across ...[15]. Serum NfL levels are elevated ... See full document
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Plasma neurofilament light as a potential biomarker of neurodegeneration in Alzheimer’s disease
... with disease progression at the stage of MCI and later ...of serum NfL concentration with the time from symptom onset in FAD ...In multiple sclerosis, CSF NfL re- flects acute axonal damage, ... See full document
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Cerebrospinal fluid in the differential diagnosis of Alzheimer’s disease: clinical utility of an extended panel of biomarkers in a specialist cognitive clinic
... MNR reports consultancy fees from Servier and Merck, paid to the institution outside the submitted work. KB is co-founder of Brain Biomarker Solutions, a GU Holding-based platform company at the University of Gothenburg, ... See full document
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Clinical efficacy issues in the treatment of multiple sclerosis: update of natalizumab
... the disease and the known differences of what is more important for patients and physicians led many neurologists to include the use of scales assessing the personal perception of the disease in their ... See full document
10
The role of neurofilament aggregation in neurodegeneration: lessons from rare inherited neurological disorders
... by protein kinase A (PKA), protein kinase C (PKC) and cal- cium/calmodulin dependent protein kinase II (CAMKII) ...mitogen-activated protein kinases (MAPKs) ... See full document
18
Repeated lumbar punctures within 3 days may affect CSF biomarker levels
... We would now like to alert the research community of an apparent effect of repeated LPs on CSF biomarker concentrations. It is also worth noting that we used a “non-traumatic” needle type. Using standard needles ... See full document
11
Plasma proteome analysis in HTLV 1 associated myelopathy/tropical spastic paraparesis
... kDa protein peak, identified as Apolipoprotein-AII (Apo-AII), was also of particular interest as it was more abundant in asymptomatic carriers than in patients with ... See full document
7
An Atypical Presentation of Multiple Sclerosis
... We demonstrated a possibility of Multiple Sclerosis presenting with severe headache and vomiting. MS exerts a considerable socioeconomic burden on society by affecting the adult in the prime of their ... See full document
18
Neurofilament light chain is a promising serum biomarker in spinocerebellar ataxia type 3
... attenuated disease progression attenuated in an SCA3 mouse model ...elevated serum NfL in the late stage of preclinical SCA3 ...that serum NfL is a promising peripheral sero- logical indicator to ... See full document
7
Profile of oral laquinimod and its potential in the treatment of multiple sclerosis
... also a multicenter and multinational trial, and enrolled 306 eligible patients with RRMS, aged 18–50 years, with an Expanded Disability Status Score of 1–5. The main inclusion criteria were different from those of the ... See full document
11
Neuroimmune interaction between multiple sclerosis and inflammatory bowel disease
... bowel disease is represented by two well-known diseases: ulcerative colitis and Crohn’s ...bowel disease and its rela- tionship to the immunological behavior of multiple ... See full document
52
Does neuroinflammation fan the flame in neurodegenerative diseases?
... microglial activity may promote conversion of diffuse plaques into neuritic plaques, an important caveat of this study is that this conclusion is based on correlative obser- vations postmortem and were not derived ... See full document
11
Factors associated with benign multiple sclerosis in the New York State MS Consortium (NYSMSC)
... Although various definitions for the classification have been proposed, BMS is generally characterized by the lack of disease progression and minimal disability 10 years or more after disease onset [2, 19, ... See full document
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