[PDF] Top 20 Preservar la calidad y salud de los suelos: una oportunidad para la Argentina
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Emodin induces apoptosis of human cervical cancer hela cells via intrinsic mitochondrial and extrinsic death receptor pathway
... medicines. Emodin (1, 3, 8-trihydroxy-6-methyl-anthraquinone), a naturally occurring anthraquinone, present in the roots and barks of numerous plants, is an active ingredient of various Chinese herbs including ... See full document
11
So Cheong Ryong Tang induces apoptosis through activation of the intrinsic and extrinsic apoptosis pathways, and inhibition of the PI3K/Akt signaling pathway in non small cell lung cancer A549 cells
... of cancer is characteristically linked to a resistance to apoptosis, a major type of cell death that occurs when DNA damage is ...irreversible. Apoptosis is characterized by distinct ... See full document
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Original Article Ponicidin induces apoptosis of human cervical cancer HeLa cell line through the PI3K/Akt and MAPK signaling pathways
... of cervical can- cers [3]. Apoptosis, otherwise known as pro- grammed cell death, plays an essential role in the anticancer properties of many anticancer molecules by preventing or controlling abnor- ... See full document
95
Breast cancer: Small molecules targeting apoptosis, a prospective approach to safe scientific success
... factor-related apoptosis-inducing lig- and (TRAIL) induces programmed cell death prefer- entially in tumour ...a cancer therapeutic due to its highly selective apop- tosis-inducing action on ... See full document
130
Guibitang, a traditional herbal medicine, induces apoptotic death in A431 cells by regulating the activities of mitogen activated protein kinases
... the extrinsic apoptotic pathway, suggesting that GBT acti- vates extrinsic apoptosis to have anti-cancer effects on A431 ...cisplatin-induced apoptosis of HeLa ... See full document
12
<em>Phyllostachys edulis</em> extract induces apoptosis signaling in osteosarcoma cells, associated with AMPK activation
... MG-63 cells were treated with serial concentrations of PEE (50, 100, 200, and 400 µ g/mL) for 24 and 48 hours, and subsequently measured for the cell ...MG-63 cells exposed to PEE for both 24 and 48 hours ... See full document
10
Aeroallergen Der p 2 induces apoptosis of bronchial epithelial BEAS-2B cells via activation of both intrinsic and extrinsic pathway
... cell death, cell cycle distribution analysis was performed and the results revealed that rDP2 dose-dependently elevated sub- G1 phase up to ...cell death and consequently reduced the cell viability of ... See full document
5
Arsenic trioxide induces cell cycle arrest and affects Trk receptor expression in human neuroblastoma SK-N-SH cells
... gression via intensification of therapy and efforts to treat minimal residual disease, more than 50% of patients will relapse and die from their malignancies ... See full document
7
Original Article Fangchinoline induces cell apoptosis via the mitochondrial apoptotic pathway in gastric cancer cells
... cell apoptosis induction potential in gastric cancer ...The mitochondrial apopto- sis pathway is mostly controlled by the interplay between members of the Bcl-2 protein ...cell ... See full document
6
<p>The natural flavonoid glycoside vitexin displays preclinical antitumor activity by suppressing NF-κB signaling in nasopharyngeal carcinoma</p>
... colorectal cancer, 14 leukemia, 15 glioblastoma, 16 bladder cancer 17 and breast cancer, 18 which further supported our research that vitexin had signi fi cant antitumor ... See full document
5
ERK-mediated autophagy promotes inactivated Sendai virus (HVJ-E)-induced apoptosis in HeLa cells in an Atg3-dependent manner
... treated HeLa cells with different MOI HVJ-E and observed the expres- sion levels of key proteins in the ...Untreated cells were used as ...autophagy, cells were treated with either 740 Y-P, ... See full document
18
Biphasic onset of splenic apoptosis following hemorrhagic shock: critical implications for Bax, Bcl 2, and Mcl 1 proteins
... thymocyte apoptosis, which is assumed to contribute to the deregulation of immune responses and the development of post-traumatic immuno- suppression ...injury, apoptosis also can be induced in liver [6], ... See full document
188
Investigation of the apoptotic way induced by digallic acid in human lymphoblastoid TK6 cells
... Cells, treated with different concentrations of DGA (2.5, 5 and 10 μg/ml) for 6, 24 and 48 h as well as control cells treated with 0.5% DMSO, were lysed with a lysis buffer (62.5 mM Tris HCl and 6 M urea, ... See full document
76
Computational prediction and experimental validation of a novel synthesized pan-PIM inhibitor PI003 and its apoptosis-inducing mechanisms in cervical cancer
... of HeLa and C4-I cells treated with PI003 and P9 were carried out by MTT analysis and the effect of PI003 gained remarkably both in HeLa and C4-I cells (Figure ...in HeLa and C4-I ... See full document
48
Trans-vaccenic acid inhibits proliferation and induces apoptosis of human nasopharyngeal carcinoma cells via a mitochondrial-mediated apoptosis pathway
... NPC cells viability, we treated two human NPC cell line subtypes, 5-8F and CNE-2 (highly metastatic strain) with TFAs using a range of ...of cells was significantly lower in the low-dose TVA (50 μM) ... See full document
84
miR-342 overexpression results in a synthetic lethal phenotype in BRCA1 -mutant HCC1937 breast cancer cells
... estrogen receptor (ER) status in breast cancer, where it is highest in ER-positive and lowest in triple-negative ...breast cancer cell lines MDA-MB-231 and HCC1937, the latter carrying a germ-line ... See full document
96
Zerumbone-loaded nanostructured lipid carrier induces G2/M cell cycle arrest and apoptosis via mitochondrial pathway in a human lymphoblastic leukemia cell line
... of apoptosis, including membrane blebbing and hole formation after 24 hours of ...the cells showed shrink- age and increased surface irregularities, with larger holes, cytoplasmic extensions, and formation ... See full document
8
Recent progress in fungus-derived bioactive agents for targeting of signaling machinery in cancer cells
... Wnt-induced intracellular signaling is an extensively stud- ied mechanism reported to underpin the development and progression of cancer. β -catenin, a well-known downstream effector, is reported to be modulated ... See full document
10
The Proapoptotic Bcl-2 Protein Bax Plays an Important Role in the Pathogenesis of Reovirus Encephalitis
... infected cells and slows lateral spread of reovirus to neighboring ...Ras-transformed cancer cells is caspase dependent ...for apoptosis signaling during reovirus ...in apoptosis, it is ... See full document
106
Cordycepin induces apoptosis in human pancreatic cancer cells via the mitochondrial-mediated intrinsic pathway and suppresses tumor growth in vivo
... Six- to eight-week-old BALB/c homozygous (nu/nu) nude mice (18–20 g body weight) were purchased from Shanghai SLAC Laboratory Animal Co., Ltd. (Shanghai, People’s Republic of China). The mice were maintained in a ... See full document
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