[PDF] Top 20 ¿Qué relación hay entre las disposiciones hacia las ciencias y el desarrollo de los países?
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An apoA-I mimetic peptide facilitates off-loading cholesterol from HDL to liver cells through scavenger receptor BI
... needs apoA-I to execute its full func- tion and reduce the vessel wall thickness in vivo ...with HDL fractions in mouse plasma ...of HDL, and in turn affect its function, D-4F could act either ... See full document
5
Increased apolipoprotein M induced by lack of scavenger receptor BI is not activated via HDL-mediated cholesterol uptake in hepatocytes
... RNA from mouse liver tissues or HepG2 cells was isolated according to the manufacturer’ s instructions using a total RNA purification kit (Shanghai Shenergy Biotech ...sized from 2 μg of total ... See full document
12
Simvastatin reduces atherogenesis and promotes the expression of hepatic genes associated with reverse cholesterol transport in apoE-knockout mice fed high-fat diet
... Reverse cholesterol transport (RCT) is believed to be crucial for preventing atherogenesis and hence the development of most cardiovascular ...of cholesterol from lipid-laden macrophages in the ... See full document
6
Scavenger Receptor B1 is a Potential Biomarker of Human Nasopharyngeal Carcinoma and Its Growth is Inhibited by HDL-mimetic Nanoparticles
... than HDL mim- icking peptides in several ...NPC cells and drug loading abilities of HPPS ...than HDL mimicking peptides, which often have short biologic half-lives (several minutes) [46, ...as ... See full document
64
An apoA-I mimetic peptide increases LCAT activity in mice through increasing HDL concentration
... low HDL levels in plasma ...a mimetic peptide enhance the RCT process if it only increases cholesterol efflux from peripheral cells without increasing other enzyme and ... See full document
7
Original Article Adiponectin upregulates ABCA1 expression through liver X receptor alpha signaling pathway in RAW 264.7 macrophages
... accumulate cholesterol to form foam cells in the vessel wall. HDL plays a key role in protecting against atherosclerosis mainly by RCT, a process that carries excess cholesterol from ... See full document
72
Characterization of apolipoprotein A I and A II containing lipoproteins in a new case of high density lipoprotein deficiency resembling Tangier disease and their effects on intracellular cholesterol efflux
... relatives were either normal or high. Using anti-A-I and anti-A-II immunosorbents, we found three populations of particles in IM: one contained both apo A-I and A-II, Lp(AI w AII); one contained apo ... See full document
154
ApoA-I/A-II-HDL positively associates with apoB-lipoproteins as a potential atherogenic indicator
... unesterified cholesterol and apolipopro- teins that bind to lipid by amphiphilic helices ...construction. HDL is therefore found with subsets of the particles based on parameters such as density, size, or ... See full document
10
Low apoA-I is associated with insulin resistance in patients with impaired glucose tolerance: a cross-sectional study
... The limitations of our study are as follows. First, our study population was limited to Chinese individuals. Therefore, our findings may not be directly applicable to other populations. Second, our sample size was small; ... See full document
12
Hepatic uptake of a modified low molecular weight heparin in rats
... the liver, whereas 33% was detected in ...evidence from cell culture experiments implies that reticuloendothelial cell system receptors might be involved in heparin metabolism, maleylated BSA, a substance ... See full document
5
Moving beyond LDL-C: incorporating lipoprotein particle numbers and geometric parameters to improve clinical outcomes
... (57%) cholesterol molecules per particle than are the ...were cholesterol-depleted, which demonstrates that even accurate LDL-C values will miss 20% of patients with elevated ... See full document
7
Protein markers of dysfunctional HDL in scavenger receptor class B type I deficient mice
... CE: cholesterol ester; CETP: cholesteryl ester transfer protein; FC: free cholesterol; FPLC: fast protein liquid chromatography; HDL-C: HDL-cholesterol; LC: liquid chromatography; ... See full document
7
PURIFIED FRACTIONS OF DODONAEA VISCOSA SEEDS ON ANTIDIABETIC AND ANTIHYPERLIPIDEMIC ACTIVITIES ON RATS
... The air dried coarse powdered material was subjected to Soxhlet extraction successively by using solvents of increasing polarity namely petroleum ether (60- 80 0 C), chloroform, ethanol and distilled water. All the ... See full document
8
Transport of Apolipoproteins A I and A II by Human Thoracic Duct Lymph
... Lymph high density lipoprotein particles are mostly high density lipoprotein 2b and high density lipoprotein 2a and have a greater overall relative triglyceride content and a smaller relative cholesteryl ester content ... See full document
172
Kinetic parameters for high density lipoprotein apoprotein AI and cholesteryl ester transport in the hamster
... of HDL cholesterol to the liver may follow one of several ...the HDL cholesteryl ester is transferred to triglyceride-rich lipoproteins (in exchange for triglyceride) and ultimately returned ... See full document
177
13-hydroxy linoleic acid increases expression of the cholesterol transporters ABCA1, ABCG1 and SR-BI and stimulates apoA-I-dependent cholesterol efflux in RAW264.7 macrophages
... which facilitates a bidirectional flux of free cholesterol between cells and lipoproteins, in response to PPAR agonists [40,41] is also considered to contribute to the increased macrophage ... See full document
38
Monocyte galactose/N-acetylgalactosamine-specific C-type lectin receptor stimulant immunotherapy of an experimental glioma. Part 1: stimulatory effects on blood monocytes and monocyte-derived cells of the brain
... Results from our experiments showed that an increased number of activated monocytes were associated with an increased number of ...these cells in the peripheral blood (in glioma-harboring animals) after ... See full document
83
Effects of dietary fucoxanthin on cholesterol metabolism in diabetic/obese KK-Ay mice
... D. Cholesterol levels in the blood and tissues are regulated by a balance between biosynthesis and catabolism, which primarily involve the activities of 3-hydroxy-3-methyl-glutaryl-CoA (HMG-CoA) reduc- tase and ... See full document
252
Expression of the Scavenger Receptor Class B type I (SR BI) family in Drosophila melanogaster
... Multiple orthologues of this family have been identified in inver- tebrates. In the case of the nematode C. elegans, six CD36-like proteins have been identified, which are implicated in the engulf- ment of apoptotic ... See full document
28
Hepatic expression of scavenger receptor class B type I (SR BI) is a positive regulator of macrophage reverse cholesterol transport in vivo
... to HDL in vitro (39, 40). Mice lacking SR-BI spe- cifically in bone marrow–derived cells develop accelerated athero- sclerosis compared with wild-type mice (15, 41, 42) (though this effect may depend ... See full document
258
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