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Gene expression profiling identifies distinct molecular subgroups of leiomyosarcoma with clinical relevance.
... on gene expression profiles), so perhaps a combination of markers would help to improve the accuracy of an immunohistochemical ...two subgroups, we got similar genes to the clusters of group-defining ... See full document
144
A 6-gene signature identifies four molecular subgroups of neuroblastoma
... four subgroups exist in all three data sets (Additional file ...this expression profile is sufficient for NB subtype discrimi- nation (Figure ...NTRK1 expression (corresponding to Type 1) can be ... See full document
16
Gene expression profiling predicts clinical outcome of prostate cancer
... identified molecular signatures have a sig- nificant potential for development of clinical prognostic tests suit- able for stratification of prostate cancer patients at the time of diag- nosis with respect ... See full document
92
Gene expression profiling identifies eleven DNA repair genes down regulated during mouse neural crest cell migration
... The expression of 6 of these 11 genes has not been previously reported in mouse ...in expression of adult P90 (in the AM), compared to NCCs collected at post-migratory ...transcriptional profiling of ... See full document
8
Profiling of patient-specific myocytes identifies altered gene expression in the ophthalmoplegic subphenotype of myasthenia gravis
... DAF expression in the orbital environment [9], suggests that potentiated complement mediated injury and altered healing of the EOMs may contribute to OP-MG ... See full document
5
Perspectives and limitations of gene expression profiling in rheumatology: new molecular strategies
... overview, gene expression profiling with microarrays has been applied in recent work to the identification of either diagnostic algorithms or new candidates and pathomechanisms, to functional studies ... See full document
12
Novel CD44-downstream signaling pathways mediating breast tumor invasion
... CD44 expression was associated with poor and favorable outcomes, thus indicating the dual nature of CD44 in mediating breast tumor ...the molecular mechanisms associated with CD44s downstream signaling in ... See full document
34
Prognostic Value of BAALC Expression in Pediatric Acute Myeloid Leukemia: A Systematic Review
... BAALC expression and poor response to chemotherapy in pediatric ...BAALC expression. Therefore, BAALC expression could be considered as a clinical prognostic marker for the treatment of AML ... See full document
158
Original Article Identification of a cytokine-cytokine receptor interaction gene signature for predicting clinical outcomes in patients with colorectal cancer
... Gene expression profile and corresponding clin- ical data were retrieved from the Cancer Geno- me Atlas (TCGA) thorough Cancer Genomics Browser of University of California Santa Cruz (UCSC) ...detailed ... See full document
64
MR Imaging–Based Radiomic Signatures of Distinct Molecular Subgroups of Medulloblastoma
... of distinct MB molecular ...all subgroups, partic- ularly WNT (because we had the least amount of WNT cases in this study), is needed to improve classifier training and evaluation during ...the ... See full document
142
Gene expression profiling identifies the zinc finger protein Charlatan as a regulator of intestinal stem cells in Drosophila
... Fig. 6. Loss of Chn does not cause precocious differentiation. The control flies were esg ts >GFP crossed with w – flies, and the chn Ri were esg ts >GFP crossed with UAS-chn RNAi flies. (A) The hatched flies were ... See full document
10
Microarrays in the 2010s: the contribution of microarray based gene expression profiling to breast cancer classification, prognostication and prediction
... proliferation. Gene signatures predictive of response to specifi c chemotherapy regimens have proven ...EML4-ALK gene re arrange ments as predictive markers of ALK inhibitors in non-small cell lung cancer), ... See full document
6
Comparison of visceral adipose tissue DNA methylation and gene expression profiles in female adolescents with obesity
... that expression of PPP2R5C in the liver correlated with obesity and insulin resistance in patients with obesity with or without diabetes, while knockdown in mice resulted in improved glucose metabolism and alter ... See full document
17
Gene expression profiling in the synovium identifies a predictive signature of absence of response to adalimumab therapy in rheumatoid arthritis
... and gene expression profiles of RA PBMCs are not represent- ative of these synovial tissue-specific ...synovial molecular profiles only, thereby demonstrating the power of this approach ...global ... See full document
20
Gene expression profiling of rubella virus infected primary endothelial cells of fetal and adult origin
... capsid expression analysis show that the immortalized cell lines Vero76 and A549 are in- fected more efficiently by RV than HUVEC and HSaVEC by a factor of almost ... See full document
92
Economic Evaluation of Potential Applications of Gene Expression Profiling in Clinical Oncology
... real-world clinical practice and in Canadian settings can be used to update our model and verify our ...that clinical practice patterns and therapies employed in the selected time periods in Manitoba ... See full document
77
Quantitation of ergosterol content and gene expression profile of ERG11 gene in fluconazole-resistant Candida albicans
... Minimum inhibitory concentrations (MICs) were assayed, according to recommendations provided by the Clinical and Laboratory Standards Institute (CLSI) M27-A3. The test was carried out using 96- well U-bottom ... See full document
25
Transcriptional Profiling of CD4 T Cells Identifies Distinct Subgroups of HIV-1 Elite Controllers
... transcriptional profiling was performed using WG-DASL mi- croarrays (Illumina) according to standard ...significant expression (P ⬍ ...average expression intensity for each transcript was calcu- ... See full document
166
Farewell to GBM-O: Genomic and transcriptomic profiling of glioblastoma with oligodendroglioma component reveals distinct molecular subgroups
... We performed DNA sequencing to identify coding vari- ants in 12 genes recurrently mutated in GBM (BRAF, EGFR, IDH1, IDH2, NF1, NRAS, PDGFRA, PIK3CA, PIK3R1, PTEN, RB1, TP53) [13] (Fig. 2b, Additional file 2: Table S2). ... See full document
7
Consensus Molecular Subtypes of Colorectal Cancer and their Clinical Implications
... independent molecular classification systems, based on gene expression data, into a single consensus system with four distinct groups, known as the consensus molecular subtypes (CMS); ... See full document
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