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Determination of pantoprazole in rat plasma by LC–MS/MS and its application to pharmacokinetics

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653 ISSN 0326-2383

KEY WORDS:LC-MS/MS, Pantoprazole, Pharmacokinetics, Rat plasma.

* Author to whom correspondence should be addressed. E-mail:hulufeng79@sina.com

Latin American Journal of Pharmacy

(formerly

Acta Farmacéutica Bonaerense)

Lat. Am. J. Pharm.

31

(5): 653-8 (2012)

Regular Article Received: January 15, 2012 Revised version: June 5, 2012 Accepted: June 6, 2012

Determination of Pantoprazole in Rat Plasma by LC–MS/MS

and its Application to Pharmacokinetics

Xiangjun QIU

1

, Ren-ai XU

2

, Yuancai ZHENG

2

, Haichao ZHAN

3

, Zhe WANG

3

& Lufeng HU

2

*

1

Department of Pharmacology, Medical College of Henan University of Science and Technology,

Luoyang, 471003, China

2

The First Affiliated Hospital of Wenzhou Medical College, Wenzhou, 325000, China

3

Pharmacy School of Wenzhou Medical College, Wenzhou, 325035, China

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