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Visión, Oportunidades y Transformaciones en el entorno empresarial derivados de medicina de precisión

Dr. Lluís Blanch Torra

Senior Intensive Care Medicine

Director Institut d’Investigació i Innovació Parc Taulí I3PT Coordinador Plataforma ITEMAS ISCiii

Santander, 1 de Julio del 2021

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L.Blanch is inventor of one CS Parc Taulí owned US

patent: “Method and system for managed related patient parameters provided by a monitoring device,” US Patent No. 12/538,940, and named in a provisional European patent application number EP19383116 owned by CS Parc Taulí: “A device and method for respiratory

monitoring in mechanically ventilated patients”.

L.Blanch is founder of BetterCare S.L. which is a research and development company, spin off of Corporació Sanitària Parc Taulí.

Financial Disclosures

Lluis Blanch MD, PhD

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Informe COTEC 2014...

10

28

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October & December 2018

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January to May 2019

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JAMA May 19, 2019

Derivation cohort: 20.189 patients with sepsis Validation cohort: 43.086 patients with sepsis

IL-6

Inflammatory Cytokines Across Phenotypes

Short-term Mortality by Phenotype

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Fernández-Gonzalo et al. Crit Care (2020) 24:618

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UCI/Hospital

Health 4.0

3D-printed organs Virtual &

Biosensors

New Materials

New Disciplines

Industry

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Information overload

ICU ITs

Lack of Information !

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Vital signs display

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Anderson D, et al. Crit Care Nurs Q. 2018;41:60–67

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Some hospitals...

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Follow-Me

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Sarlabous L, et al. Scientific Reports (2020) 10:13911(patent pending)

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Anna Ullastres PhD. February 11, 2020

https://www.tauli.cat/es/institut/actualitat/vigilancia-

tecnologica/2020/02/wearable-devices-in-health-are-we-ready/

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LuCaDAlert: Deep Learning para detección de Cáncer de Pulmón

Enero 2019 Abril 2019

Convolutional Neural Network

La utilización de CAD sobre 400.000 personas puede detectar precozmente 10 Ca. de Pulmón/Año y evitar 18 meses de retardo diagnóstico.

DTS 21

(ISCiii)

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Building Information Modeling

Internet of Things

Internet of Medical Devices Internet of Emotions

Digital Twins …..

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Vision of Knowledge

Cancer

Mental Health and Neuroscience

Metabolism and Digestive

Rare Diseases

Epidemiology, Care Improvement and

Chronicity Infections and

Immunology

Surgery and Interventional Procedures

R & D & I Model

IOT

VR AI

3D 5G

Participative Medicine

Preventive Medicine

Predictive Medicine Personalized

Medicine

Digital Transformation Research Areas

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IOT

VR AI

3D 5G

Ongoing Projects for Digital Transformation

R & D & I Impact

3DBonT

Weaning VR UCI QuirofAM

SIMDCAT

Personalized Surgical Guides

COVID 3DP 5G Health

Emergencies

Safety Hug

EPPICS

ICU-RGS

LuCaDAlert AI4KIDNEY

IA Medical Signals INNOBRAIN

CODIS COVID-xAI

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1953 Polio Epidemic Rancho Los Amigos Hospital California

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On 27 August 1952, Ibsen

demonstrated his anaesthetic skills on a 12-year-old girl named Vivi E., who was in a state of

severe respiratory failure. Ibsen ventilated the tracheotomised girl with a to-and-fro system, sucking the mucus from her lungs and narcotising her in order to release her bronchospasm. As it became clear that the available cuirass respirator could not provide sufficient ventilation, Ibsen continued to ventilate the girl

manually and eventually saved her life.

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COVID-19 Pandemic

Fifth Intensive Care Unit in Parc Taulí. Third Week April 2020

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Turning the crisis into an opportunity: digital health strategies deployed during the COVID-19 outbreak in Catalonia

(JMIR Preprints 03/04/2020:19106)

DOI: https://doi.org/10.2196/preprints.19106

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n engl j med 384;15 nejm.org April 15, 2021

Estimated Cost to Medicare of Remote Patient Monitoring (RPM) Services

25.4 million patients as of September 2020

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New Technological Services: 3D Lab

R & D & I Support

 Virtual surgical planning

 Printing of anatomical surgical models

 Design surgical guides

 Simulation models

 Development of tailor-made healthcare products

 Training in 3D printing

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Role of New Disciplines in ICU/Hospital/Health:

neuropsychologists, medical engineers, computer & data scientists…..

Technological Tools for the Early Prevention of the Post- Intensive Care Syndrome

Knowledge Industry grants. Producte Grants, 2019 Funding: 99.989 €

Sol Fernandez, Guillem Navarra

Grants for Research Projects in SARS-COV2 and COVID19 illness, 2020

Funding: 180.660 €

Digital therapy: EPPICS project

EPPICS software

Liberia ICU software

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Plataforma ISCIII de Dinamización e innovación de las capacidades industriales del SNS y su transferencia efectiva al sector productivo (ITEMAS) (PT20/00081) financiada por el Instituto de Salud Carlos III. Proyecto cofinanciado con el Fondo Europeo de Desarrollo Regional (FEDER).

DYNAMIZATION AND INNOVATION of the industrial capacities of the National Health System and their effective transfer to the productive sector (2021-3)

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Muchas gracias!!

Referencias

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