APPENDIX III: NMR spectra

(1)

333

APPENDIX III: NMR spectra

Index

 Enynes (1) – Chapter 1 334

 Alkylboronates (2) – Chapter 2 and 3 373

 Alkenylboronates (11) – Chapter 3 405

 Diboronates (17) – Chapter 4 416

 Carboborylative cyclization compounds (26, 28) – Chapter 5 453

 Functionalization products (3-5, 14-16, 18-21, 29, 33-36) 476

 Reductive cyclization products (13) 498

 Carbocyclization products (30) 502

 Alkynylboronates (24-25, 31-32) 504

Products from mechanistic studies

 Deuterated compounds (d²-13, d²-26) 506

 Hydroboration products (Chapter 2) 511

 Carboboration products (37-38) 513

 Ligands (IP, BIP, OP, PyBox) 514

 Other products (12aa) 517

 Propargyl alcohols and NTs derivatives (Chapter 1) 519

 Intermediate compounds for the synthesis of enynes (Chapter 1) 524

(2)

334

 Enynes (1)

1aa

1H NMR CDCl3

300 MHz

1ab

1H NMR CDCl3

300 MHz

(3)

335 1ac

1H NMR CDCl3

300 MHz

1ad

1H NMR CDCl3

300 MHz

(4)

336

1af

1H NMR CDCl3

300 MHz 1ae

1H NMR CDCl3

300 MHz

(5)

337 1ah

1H NMR CDCl3

300 MHz 1ag

1H NMR CDCl3

300 MHz

(6)

338

1ai

1H NMR CDCl3

300 MHz

1aj

1H NMR CDCl3

300 MHz

(7)

339 1ak

1H NMR CDCl3

300 MHz 1aj

13C NMR CDCl3

75 MHz

(8)

340

1am

1H NMR CDCl3

300 MHz 1al

1H NMR CDCl3

300 MHz

(9)

341 1an

1H NMR CDCl3

300 MHz

1ao

1H NMR CDCl3

300 MHz

(10)

342

1ap

1H NMR CDCl3

300 MHz 1ao

13C NMR CDCl3

75 MHz

(11)

343 1ap

13C NMR CDCl3

75 MHz

1ba

1H NMR CDCl3

300 MHz

(12)

344

1bb

1H NMR CDCl3

300 MHz

1bc

1H NMR CDCl3

300 MHz

(13)

345 1bd

1H NMR CDCl3

300 MHz

1be

1H NMR CDCl3

300 MHz

(14)

346

1bg

1H NMR CDCl3

300 MHz 1bf

1H NMR CDCl3

300 MHz

(15)

347 1bi

1H NMR CDCl3

300 MHz 1bh

1H NMR CDCl3

300 MHz

(16)

348

1bj

1H NMR CDCl3

300 MHz 1bi

13C NMR CDCl3

75 MHz

(17)

349 1bj

13C NMR CDCl3

75 MHz

1bk

1H NMR CDCl3

300 MHz

(18)

350

1bl

1H NMR CDCl3

300 MHz

1bm

1H NMR CDCl3

300 MHz

(19)

351 1bo

1H NMR CDCl3

300 MHz 1bn

1H NMR CDCl3

300 MHz

(20)

352

1bp

1H NMR CDCl3

300 MHz

1bq

1H NMR CDCl3

300 MHz

(21)

353 1br

1H NMR CDCl3

300 MHz

1br

1H NMR CDCl3

300 MHz

(22)

354

1bs

13C NMR CDCl3

75 MHz 1bs

1H NMR CDCl3

300 MHz

(23)

355 1bt

1H NMR CDCl3

300 MHz

1bt

13C NMR CDCl3

75 MHz

(24)

356

1bu

1H NMR CDCl3

300 MHz

1bv

1H NMR CDCl3

300 MHz

(25)

357 1bw

1H NMR CDCl3

300 MHz 1bv

13C NMR CDCl3

75 MHz

(26)

358

1bx

1H NMR CDCl3

300 MHz

1by

1H NMR CDCl3

300 MHz

(27)

359 1by

13C NMR CDCl3

75 MHz

1bz

1H NMR CDCl3

300 MHz

(28)

360

1ca

1H NMR CDCl3

300 MHz

1cb

1H NMR CDCl3

300 MHz

(29)

361 1cc

1H NMR CDCl3

300 MHz

1cd

1H NMR CDCl3

300 MHz

(30)

362

1ce

1H NMR CDCl3

300 MHz

1cf

1H NMR CDCl3

300 MHz

(31)

363 1cg

1H NMR CDCl3

300 MHz

1ch

1H NMR CDCl3

300 MHz

(32)

364

1da

1H NMR CDCl3

300 MHz 1ci

1H NMR CDCl3

300 MHz

(33)

365 1db

1H NMR CDCl3

300 MHz

1ea

1H NMR CDCl3

300 MHz

(34)

366

d²-1ea

1H NMR CDCl3

300 MHz

d²-1ea

2H NMR CDCl3

77 MHz

(35)

367 1eb

1H NMR CDCl3

300 MHz d²-1ea

13C NMR CDCl3

75 MHz

(36)

368

1ec

1H NMR CDCl3

300 MHz

1ec

13C NMR CDCl3

75 MHz

(37)

369 1fa

1H NMR CDCl3

300 MHz 1ed

1H NMR CDCl3

300 MHz

(38)

370

1fb

1H NMR CDCl3

300 MHz

1ga

1H NMR CDCl3

300 MHz

(39)

371 1gb

13C NMR CDCl3

75 MHz 1gb

1H NMR CDCl3

300 MHz

(40)

372

1gd

1H NMR CDCl3

300 MHz 1gc

1H NMR CDCl3

300 MHz

(41)

373

 Alkylboronates (2)

2aa

1H NMR CDCl3

300 MHz

2aa

13C NMR CDCl3

75 MHz

(42)

374

2ab

1H NMR CDCl3

300 MHz

2ab

13C NMR CDCl3

75 MHz

(43)

375 2ac

1H NMR CDCl3

300 MHz

2ac

13C NMR CDCl3

75 MHz

(44)

376

2ad

1H NMR CDCl3

300 MHz

2ad

13C NMR CDCl3

75 MHz

(45)

377 2ae

13C NMR CDCl3

75 MHz 2ae

1H NMR CDCl3

300 MHz

(46)

378

2af

13C NMR CDCl3

75 MHz 2af

1H NMR CDCl3

300 MHz

(47)

379 2ag

1H NMR CDCl3

300 MHz

2ag

13C NMR CDCl3

75 MHz

(48)

380

2ag

1H-¹H COSY CDCl3

2ag

1H-¹³C HMQC CDCl3

(49)

381 2ag

1H-¹³C HMBC CDCl3

2ah

1H NMR CDCl3

300 MHz

(50)

382

2ao

1H NMR CDCl3

300 MHz 2ah

13C NMR CDCl3

75 MHz

(51)

383 2ap

1H NMR CDCl3

300 MHz 2ao

13C NMR CDCl3

75 MHz

(52)

384

2bb

1H NMR CDCl3

300 MHz 2ap

13C NMR CDCl3

75 MHz

(53)

385 2bc

1H NMR CDCl3

300 MHz

2bc

13C NMR CDCl3

75 MHz

(54)

386

2bd

1H NMR CDCl3

300 MHz

2bd

13C NMR CDCl3

75 MHz

(55)

387 2be

1H NMR CDCl3

300 MHz

2be

13C NMR CDCl3

75 MHz

(56)

388

2bf

1H NMR CDCl3

300 MHz

2bf

13C NMR CDCl3

75 MHz

(57)

389 2bg

1H NMR CDCl3

300 MHz

2bg

13C NMR CDCl3

75 MHz

(58)

390

2bh

1H NMR CDCl3

300 MHz

2bh

13C NMR CDCl3

75 MHz

(59)

391 2bi

1H NMR d⁶-DMSO

300 MHz

2bi

13C NMR CDCl3

75 MHz

(60)

392

2bj

1H NMR CDCl3

300 MHz

2bj

13C NMR CDCl3

75 MHz

(61)

393 2bl

1H NMR CDCl3

300 MHz

2bl

13C NMR CDCl3

75 MHz

(62)

394

2bn

1H NMR CDCl3

300 MHz

2bn

13C NMR CDCl3

75 MHz

(63)

395 2cc

1H NMR CDCl3

300 MHz

2cd

1H NMR CDCl3

300 MHz

(64)

396

2ce

1H NMR CDCl3

300 MHz 2cd

13C NMR CDCl3

75 MHz

(65)

397 2cf

1H NMR CDCl3

300 MHz 2ce

13C NMR CDCl3

75 MHz

(66)

398

2cf

13C NMR CDCl3

75 MHz

2cg

1H NMR CDCl3

300 MHz

(67)

399 2da

1H NMR CDCl3

300 MHz

2da

13C NMR CDCl3

75 MHz

(68)

400

2db

1H NMR CDCl3

300 MHz

2db

13C NMR CDCl3

75 MHz

(69)

401 2ea

1H NMR CDCl3

300 MHz

2ea

13C NMR CDCl3

75 MHz

(70)

402

2eb

1H NMR CDCl3

300 MHz

2eb

13C NMR CDCl3

75 MHz

(71)

403 2fa

1H NMR CDCl3

300 MHz

2fa

13C NMR CDCl3

75 MHz

(72)

404

2fb

1H NMR CDCl3

300 MHz

2fb

13C NMR CDCl3

75 MHz

(73)

405

 Alkenylboronates (11)

11an

1H NMR CDCl3

300 MHz

11an

13C NMR CDCl3

75 MHz

(74)

406

11bn

1H NMR CDCl3

300 MHz

1bo

1H NMR CDCl3

300 MHz

(75)

407 1bn

13C NMR CDCl3

75 MHz

11bp

1H NMR CDCl3

300 MHz

(76)

408

11bp

13C NMR CDCl3

75 MHz

11br

1H NMR CDCl3

300 MHz

(77)

409 11bs

1H NMR CDCl3

300 MHz 11br

13C NMR CDCl3

75 MHz

(78)

410

11bw

1H NMR CDCl3

300 MHz 11bs

13C NMR CDCl3

75 MHz

(79)

411 11bw

13C NMR CDCl3

75 MHz

11bx

1H NMR CDCl3

300 MHz

(80)

412

11bx

13C NMR CDCl3

75 MHz

11by

1H NMR CDCl3

300 MHz

(81)

413 11bz

1H NMR CDCl3

300 MHz 11by

13C NMR CDCl3

75 MHz

(82)

414

11cc

1H NMR CDCl3

300 MHz 11bz

13C NMR CDCl3

75 MHz

(83)

415 11cc

13C NMR CDCl3

75 MHz

(84)

416

 Diboronates (17)

17aa

1H NMR CDCl3

300 MHz

17aa

13C NMR CDCl3

75 MHz

(85)

417 17ab

1H NMR CDCl3

300 MHz

17ab

13C NMR CDCl3

75 MHz

(86)

418

17ac

1H NMR CDCl3

300 MHz

17ac

13C NMR CDCl3

75 MHz

(87)

419 17ad

1H NMR CDCl3

300 MHz

17ad

13C NMR CDCl3

75 MHz

(88)

420

17af

1H NMR CDCl3

300 MHz

17af

13C NMR CDCl3

75 MHz

(89)

421 17ah

1H NMR CDCl3

300 MHz

17ah

13C NMR CDCl3

75 MHz

(90)

422

17an

1H NMR CDCl3

300 MHz

17an

13C NMR CDCl3

75 MHz

(91)

423 17bb

1H NMR CDCl3

300 MHz

17bb

13C NMR CDCl3

75 MHz

(92)

424

17bc

1H NMR CDCl3

300 MHz

17bc

13C NMR CDCl3

75 MHz

(93)

425 17bd

1H NMR CDCl3

300 MHz

17bd

13C NMR CDCl3

75 MHz

(94)

426

17be

1H NMR CDCl3

300 MHz

17be

13C NMR CDCl3

75 MHz

(95)

427 17bg

1H NMR CDCl3

300 MHz

17bg

13C NMR CDCl3

75 MHz

(96)

428

17bm

1H NMR CDCl3

300 MHz

17bm

13C NMR CDCl3

75 MHz

(97)

429 17bn

1H NMR CDCl3

300 MHz

17bn

13C NMR CDCl3

75 MHz

(98)

430

17bo

1H NMR CDCl3

300 MHz

17bo

13C NMR CDCl3

75 MHz

(99)

431 17bp

1H NMR CDCl3

300 MHz

17bp

13C NMR CDCl3

75 MHz

(100)

432

17br

1H NMR CDCl3

300 MHz

17br

13C NMR CDCl3

75 MHz

(101)

433 17bt

1H NMR CDCl3

300 MHz

17bt

13C NMR CDCl3

75 MHz

(102)

434

17bu

1H NMR CDCl3

300 MHz

17bu

13C NMR CDCl3

75 MHz

(103)

435 17bv

1H NMR CDCl3

300 MHz

17bv

13C NMR CDCl3

75 MHz

(104)

436

17bv

1H-¹H COSY CDCl3

17bv

1H-¹³C HMQC CDCl3

(105)

437 17bw

1H NMR CDCl3

300 MHz

17bw

13C NMR CDCl3

75 MHz

(106)

438

17bx

1H NMR CDCl3

300 MHz

17bx

13C NMR CDCl3

75 MHz

(107)

439 17by

1H NMR CDCl3

300 MHz

17by

13C NMR CDCl3

75 MHz

(108)

440

17by

1H-¹H COSY CDCl3

17by

1H-¹³C HMQC CDCl3

(109)

441 17bz

1H NMR CDCl3

300 MHz

17bz

13C NMR CDCl3

75 MHz

(110)

442

17bz

1H-¹H COSY CDCl3

17bz

1H-¹³C HMQC CDCl3

(111)

443 17ca

1H NMR CDCl3

300 MHz

17ca

13C NMR CDCl3

75 MHz

(112)

444

17cb

1H NMR CDCl3

300 MHz

17cb

13C NMR CDCl3

75 MHz

(113)

445 17cc

1H NMR CDCl3

300 MHz

17cc

13C NMR CDCl3

75 MHz

(114)

446

17cd

1H NMR CDCl3

300 MHz

17cd

13C NMR CDCl3

75 MHz

(115)

447 17ce

1H NMR CDCl3

300 MHz

17ce

13C NMR CDCl3

75 MHz

(116)

448

17cf

1H NMR CDCl3

300 MHz

17cf

13C NMR CDCl3

75 MHz

(117)

449 17db

1H NMR CDCl3

300 MHz

17db

13C NMR CDCl3

75 MHz

(118)

450

17ea

1H NMR CDCl3

300 MHz

17ea

13C NMR CDCl3

75 MHz

(119)

451 17eb

1H NMR CDCl3

300 MHz

17eb

13C NMR CDCl3

75 MHz

(120)

452

17ed

1H NMR CDCl3

300 MHz

17ed

13C NMR CDCl3

75 MHz

(121)

453

 Carboboration compounds (26, 28)

26aa

1H NMR CDCl3

300 MHz

26aa

13C NMR CDCl3

75 MHz

(122)

454

26ba

1H NMR CDCl3

300 MHz

26ba

13C NMR CDCl3

75 MHz

(123)

455 26bd

1H NMR CDCl3

300 MHz

26bd

13C NMR CDCl3

75 MHz

(124)

456

26bl

1H NMR CDCl3

300 MHz

26bl

13C NMR CDCl3

75 MHz

(125)

457 26bo

1H NMR CDCl3

300 MHz

26bo

13C NMR CDCl3

75 MHz

(126)

458

26bq

1H NMR CDCl3

300 MHz

26bq

13C NMR CDCl3

75 MHz

(127)

459 26bw

1H NMR CDCl3

300 MHz

26bw

13C NMR CDCl3

75 MHz

(128)

460

26by

13C NMR CDCl3

75 MHz 26by

1H NMR CDCl3

300 MHz

(129)

461 major diast

26bz

13C NMR CDCl3

75 MHz 26bz

1H NMR CDCl3

300 MHz

(130)

462

26bz

1H NMR CDCl3

300 MHz

minor diast 26bz

13C NMR CDCl3

75 MHz

(131)

463 26cb

1H NMR CDCl3

300 MHz

26cb

13C NMR CDCl3

75 MHz

(132)

464

26ce

1H NMR CDCl3

300 MHz

26ce

13C NMR CDCl3

75 MHz

(133)

465 26ci

1H NMR CDCl3

300 MHz

26ci

13C NMR CDCl3

75 MHz

(134)

466

Compound 26ea:

1H NMR (300 MHz, CDCl3) δ 7.36 – 7.28 (m, 4H, 11 + 12), 7.24 – 7.14 (m, 1H, 13), 6.54 (s, 1H, 3), 3.16 (d, J = 4.6 Hz, 1H, 1), 3.03 – 2.90 (m, 1H, 4), 2.70 – 2.56 (m, 1H, 7), 2.24 – 2.02 (m, 3H, 7 + 5), 1.76 – 1.50 (m, 2H, 6), 1.30 (s, 12H, 16), -0.19 (s, 9H, 14).

13C NMR (75 MHz, CDCl3) δ 143.4 (C, 10), 141.2 (CH, 3), 134.4 (C, 8), 131.1 (C, 9), 128.9 (2  CH, 12), 127.8 (2  CH, 11), 126.2 (CH, 13), 83.4 (2  C, 15), 43.8 (CH, 4), 40.0 (CH, 1), 32.3 (CH2, 7), 29.7 (CH2, 5), 25.2 (2  CH3, 16), 25.1 (2  CH3, 16), 24.0 (CH2, 6), -1.30 (3  CH3, 14). [C assigned as 2 does not appear in the spectra due to line broadening].

26ea

1H NMR CDCl3

300 MHz

3 1 11+12

1 3

4 7 7+5 6

16 14

(135)

467 26ea

13C NMR CDCl3

75 MHz

26ea

1H-¹H COSY CDCl3

14 16

5 6 1 7 4 15

13 12 11 8 9 10

3

(136)

468

26ea

1H-¹³C HMQC CDCl3

26ea

1H-¹³C HMBC CDCl3

(137)

469 26eb

1H NMR CDCl3

300 MHz

26eb

13C NMR CDCl3

75 MHz

(138)

470

26ec

1H NMR CDCl3

300 MHz

26ec

13C NMR CDCl3

75 MHz

(139)

471 26ed

1H NMR CDCl3

300 MHz

26ed

13C NMR CDCl3

75 MHz

(140)

472

26fb

1H NMR CDCl3

300 MHz

26fb

13C NMR CDCl3

75 MHz

(141)

473 28cf

1H NMR CDCl3

300 MHz

28cf

13C NMR CDCl3

75 MHz

(142)

474

28cf

1H-¹³C HMQC CDCl3

28cf

1H-¹H COSY CDCl3

(143)

475 28cf

1H-¹³C HMBC CDCl3

(144)

476

 Functionalization products (3-5, 14-16, 18-21, 29, 33-36)

3aa

1H NMR CDCl3

300 MHz

3bb

1H NMR CDCl3

300 MHz

(145)

477 4aa

1H NMR d⁶-DMSO

300 MHz

4aa

13C NMR d⁶-DMSO 75 MHz

(146)

478

4bb

1H NMR d⁶-DMSO

300 MHz

4cc

1H NMR d⁶-DMSO

300 MHz

(147)

479 4cc

13C NMR d⁶-DMSO 75 MHz

5aa

1H NMR CDCl3

300 MHz

(148)

480

5aa

13C NMR CDCl3

75 MHz

5bb

1H NMR CDCl3

300 MHz

(149)

481 5cc

1H NMR CDCl3

300 MHz 5bb

13C NMR CDCl3

75 MHz

(150)

482

5cc

13C NMR CDCl3

75 MHz

14bn

1H NMR CDCl3

300 MHz

(151)

483 15bn

1H NMR CDCl3

300 MHz

15bn

13C NMR CDCl3

75 MHz

(152)

484

16bn

1H NMR CDCl3

300 MHz

16bn

13C NMR CDCl3

75 MHz

(153)

485 18bd

1H NMR CDCl3

300 MHz

18bd

13C NMR CDCl3

75 MHz

(154)

486

19cb

1H NMR CDCl3

300 MHz

19cb

13C NMR CDCl3

75 MHz

(155)

487 19cc

1H NMR CDCl3

300 MHz

19cc

13C NMR CDCl3

75 MHz

(156)

488

20cb

1H NMR d⁶-Acetone

300 MHz

20cb

13C NMR d⁶-Acetone

75 MHz

(157)

489 20cc

1H NMR d⁶-Acetone

300 MHz

20cc

13C NMR d⁶-Acetone

75 MHz

(158)

490

21cb

1H NMR CDCl3

300 MHz

21cb

13C NMR CDCl3

75 MHz

(159)

491 21cc

1H NMR CDCl3

300 MHz

21cc

13C NMR CDCl3

75 MHz

(160)

492

29bd

1H NMR CDCl3

300 MHz

29bd

13C NMR CDCl3

75 MHz

(161)

493 29ea

1H NMR CDCl3

300 MHz

29ea

13C NMR CDCl3

75 MHz

(162)

494

33bd

1H NMR CDCl3

300 MHz

33bd

13C NMR CDCl3

75 MHz

(163)

495 34ea

1H NMR CDCl3

300 MHz

34ea

13C NMR CDCl3

75 MHz

(164)

496

35ea

1H NMR CDCl3

300 MHz

35ea

13C NMR CDCl3

75 MHz

(165)

497 36ea

1H NMR CDCl3

300 MHz

36ea

13C NMR CDCl3

75 MHz

(166)

498

 Reductive cyclization products (13)

13ga

1H NMR CDCl3

300 MHz 13aa

1H NMR CDCl3

300 MHz

(167)

499 13ga

13C NMR CDCl3

75 MHz

13gb

1H NMR CDCl3

300 MHz

(168)

500

13gc

1H NMR CDCl3

300 MHz

13gc

13C NMR CDCl3

75 MHz

(169)

501 13gd

1H NMR CDCl3

300 MHz

13gd

13C NMR CDCl3

75 MHz

(170)

502

 Carbocyclization products (30)

30gb

1H NMR CDCl3

300 MHz

30gb

13C NMR CDCl3

75 MHz

(171)

503 30gc

1H NMR CDCl3

300 MHz

30gc

13C NMR CDCl3

75 MHz

(172)

504

 Alkynylboronates (24-25, 31-32)

24

1H NMR CDCl3

300 MHz

25

1H NMR CDCl3

300 MHz

(173)

505 31

1H NMR CDCl3

300 MHz

32

1H NMR CDCl3

300 MHz

(174)

506

 Deuterated compounds (d²-13, d²-26)

d²-13bb

1H NMR CDCl3

300 MHz

d²-13bb

2H NMR CDCl3

77 MHz

(175)

507 d²-13bb

13C NMR CDCl3

75 MHz

d²-13cc

1H NMR CDCl3

300 MHz

(176)

508

d²-13cc

2H NMR CDCl3

77 MHz

d²-13cc

13C NMR CDCl3

75 MHz

(177)

509 d²-26ea

1H NMR CDCl3

300 MHz

d²-26ea

2H NMR CDCl3

77 MHz

(178)

510

d²-26ea

13C NMR CDCl3

75 MHz

(179)

511

 Hydroboration products

1H NMR CDCl3

300 MHz

1H NMR CDCl3

300 MHz

(180)

512

1H NMR CDCl3

300 MHz

(181)

513

 Carboboration products (37-38)

37

1H NMR CDCl3

300 MHz

38

1H NMR CDCl3

300 MHz

(182)

514

 Ligands (IP, BIP, OP, PyBox)

IP(H)

1H NMR CDCl3

300 MHz

IP(Me)

1H NMR CDCl3

300 MHz

(183)

515 OP

1H NMR CDCl3

300 MHz BIP

1H NMR CDCl3

300 MHz

(184)

516

s-BuPyBox

1H NMR CDCl3

300 MHz

t-BuPyBox

1H NMR CDCl3

300 MHz

(185)

517

 Other products

12aa

1H NMR CDCl3

300 MHz

1H NMR CDCl3

300 MHz

(186)

518

13C NMR CDCl3

75 MHz

(187)

519

 Propargylic alcohols and NTs derivatives

1H NMR CDCl3

300 MHz

1H NMR CDCl3

300 MHz

(188)

520

1H NMR CDCl3

300 MHz

1H NMR CDCl3

300 MHz

(189)

521

1H NMR CDCl3

300 MHz

1H NMR CDCl3

300 MHz

(190)

522

1H NMR CDCl3

300 MHz

1H NMR CDCl3

300 MHz

(191)

523

1H NMR CDCl3

300 MHz

1H NMR CDCl3

300 MHz

(192)

524

 Intermediate compounds for the synthesis of enynes

1H NMR CDCl3

300 MHz

1H NMR CDCl3

300 MHz

(193)

525

1H NMR CDCl3

300 MHz

1H NMR CDCl3

300 MHz

(194)

526

1m

1H NMR CDCl3

300 MHz