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Antiplasmodial and Cytotoxic Activity of Piper Piedecuestanum Trel and Yunck

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(2) Research Journal of Medicinal Plants. OPEN ACCESS. ISSN 1819-3455 DOI: 10.3923/rjmp.2018.57.64. Research Article Antiplasmodial and Cytotoxic Activity of Piper Piedecuestanum Trel. and Yunck 1,2. Ana María Mesa Vanegas, 1Jhon Fredy Toro Suaza, 1Ana María Vásquez Cardona, 1Silvia Blair Trujillo, 2 Carlos Peláez Jaramillo, 3,4Santiago Díaz Oltra, 3César Augusto Pachón and 3Miguel Carda 1. Malaria Research Group, University Research Headquarters (SIU), Carrera 62 52-59, Tower 1, Lab. 610 SIU, Faculty of Medicine, University of Antioquia, A.A 1226, Medellín, Colombia 2 Interdisciplinary Group of Molecular Studies GIEM, Faculty of Exact and Natural Sciences, University of Antioquia, A.A 1226, Medellín, Colombia 3 Department of Inorganic and Organic Chemistry, Universitat Jaume I, 12071, Castellón, Spain 4 Department of Education, Universitat Jaume I, 12071, Castellón, Spain. G. G. G.

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(4) E E. deExtraction (%) . Extracts weight  100 Weight of plant material. G. δ δ. δ. δ. δ. δ.

(5) δ E δ. G. δ. δ G G. δ G G. δ. δ G G. G GG. E. E.

(6) G. G E. G. G E. G. G. G. G. G. G. G. G. G. G. G. E E E E E G. G GG. G G. G. G G G. G G. G.

(7) G. G. OH O. H3CO. OH. O. OH H3CO. O. H3CO OH. O. O. H3CO H3CO OH. O O. H3CO H3CO OH. O O. H3CO. OH. O. Br O. H3CO H3CO OH. O. G. G. G. G. 100. IC50 CC50 U-937 CC50 HUVEG. 80. G 60. G. *. 40. G. + 20. G PP H TE xt E. xt M PP H TE. PP H TE xt A. PP H TE xt D. 0 PP H Ex tH. 1. Inhibitory concentration 50 (IC50 y CC50 µg mLG ). 120. G. G. G. Extracts of different polarity P. pidecuestanum (PP). G.

(8) G G G. G. G. G. G. G. G. G.

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Figure

Fig. 1: Comparison    of  the  antiplasmodial  and cytotoxic activity       of     extracts     of     different     polarity     of P

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