[PDF] Top 20 Adolescentes en riesgo psicosocial y resiliencia
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AB Initio Structural Analysis on Envelope (E) Glycoprotein of Dengue Virus (DENV) Type 1-4
... of DENV can trigger cellular immune responses and subsequently the development of a severe ...products, DENV entry inhibitors. Inhibition of DENV attachment and entry into the host cell can inhibit ... See full document
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Variable Surface Epitopes in the Crystal Structure of Dengue Virus Type 3 Envelope Glycoprotein
... different dengue virus serotypes. Structural features on the surface of the virion determine the specificity with which a given antibody will ...four dengue virus serotypes mean that ... See full document
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Dengue virus non-structural protein 1: a pathogenic factor, therapeutic target, and vaccine candidate
... against DENV infection in different studies. Antibodies targeting structural proteins, such as envelope and prM/M, have been characterized; these antibodies are termed “neutraliz- ing antibodies” due ... See full document
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Dengue Virus Envelope Dimer Epitope Monoclonal Antibodies Isolated from Dengue Patients Are Protective against Zika Virus
... between DENV and ZIKV, we tested a large panel of well-characterized human and mouse MAbs for binding and neu- tralization of two strains of ZIKV: a French Polynesian 2013 strain representing the Asiatic lineage ... See full document
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Monkeys immunized with intertypic chimeric dengue viruses are protected against wild-type virus challenge.
... four dengue virus serotypes (DEN1 to DEN4) form a subgroup within the Flavivirus ...genus. Dengue virus causes more human illness than any other ...The virus is transmitted from human ... See full document
Neutralization of diverse human immunodeficiency virus type 1 variants by an anti-V3 human monoclonal antibody.
... With human immunodeficiency virus type 1 HIV-1, potent neutralization of virus infectivity has been associated primarily with Abs to two regions of the gpl20 envelope glycoprotein: the C[r] ... See full document
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Structural and Functional Analysis of Interhelical Interactions in the Human Immunodeficiency Virus Type 1 gp41 Envelope Glycoprotein by Alanine-Scanning Mutagenesis
... (Fig. 1). Sequence comparisons among HIV-1 isolates and between HIV-1 and simian immunodeficiency virus (SIV) show that the residues at these contact positions are highly conserved ...the ... See full document
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Determinants of Neutralization Resistance in the Envelope Glycoproteins of a Simian-Human Immunodeficiency Virus Passaged In Vivo
... The amounts of soluble 89.6 and KB9 gp120 glycoproteins in the supernatants were estimated by precipitation with an excess of serum from an HIV-1-infected individual. The estimates were used to adjust the amounts ... See full document
14
Characterization of hepatitis C virus envelope glycoprotein complexes expressed by recombinant vaccinia viruses.
... Similarly, expression of the envelope proteins of the flavivirus dengue type 4 2, 25 or the pestivirus hog cholera virus 31 as intracellular species by live recombinant vaccinia virus ve[r] ... See full document
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Calcium ions are required for cell fusion mediated by the CD4-human immunodeficiency virus type 1 envelope glycoprotein interaction.
... To examine the role of calcium ions for cell fusion mediated by interactions between CD4 and the human immunodeficiency virus type 1 HIV-1 envelope glycoprotein gpl20-gp4l, we used two e[r] ... See full document
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Human immunodeficiency virus type 1 envelope glycoprotein molecules containing membrane fusion-impairing mutations in the V3 region efficiently undergo soluble CD4-stimulated gp120 release.
... Plasmid pPE7H contains the HIV-1 envelope Human immunodeficiency virus type 1 HIV-1 infection is initiated by binding of the viral envelope glycoprotein to CD4 molecules on the surface o[r] ... See full document
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Analysis of the interaction of the human immunodeficiency virus type 1 gp120 envelope glycoprotein with the gp41 transmembrane glycoprotein.
... gp120 glycoprotein, since, in contrast to shedding, it occurs efficiently at 4°C, in the absence of the conserved stem of the V1/V2 stem-loop, and with the envelope glycoproteins from a primary ... See full document
Epitope Determinants of a Chimpanzee Dengue Virus Type 4 (DENV-4)-Neutralizing Antibody and Protection against DENV-4 Challenge in Mice and Rhesus Monkeys by Passively Transferred Humanized Antibody
... of DENV E is beginning to emerge from epitope analysis of antibodies recovered from DENV-infected chimpanzees by repertoire cloning (9, 10, ...potent, DENV-4-neutralizing MAb ... See full document
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Minimal Requirement for a Lentivirus Vector Based on Human Immunodeficiency Virus Type 1
... FIG. 1. Basic components of the packaging system. Vector genome plasmids pH5Z, pH3Z, and pH4Z were derived from pWI3 (24) and inserted into pBlue- script KS1 (Stratagene). They have a number of structural ... See full document
Introduction of Exogenous Epitopes in the Variable Regions of the Human Immunodeficiency Virus Type 1 Envelope Glycoprotein: Effect on Viral Infectivity and the Neutralization Phenotype
... functional trimeric Env spike, and as a result, the V4 HA- tagged SF162 and SF33 viruses were resistant to neutralization by the anti-HA MAb used here. We believe that the positions within the V4 loop where the tags were ... See full document
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The Infectious Molecular Clone and Pseudotyped Virus Models of Human Immunodeficiency Virus Type 1 Exhibit Significant Differences in Virion Composition with Only Moderate Differences in Infectivity and Inhibition Sensitivity
... In both sets of data, the overall profile of neutralization/ inhibition sensitivity was generally similar between the matched IMC and PV. The 50% inhibitory concentrations for all but one analysis were less than ... See full document
178
Effect of medicinal plants on Dengue: Review article
... named dengue virus (DENV), transmitted by the Aedes aegypti mosquito ...date, 4 antigenically related but distinct virus serotypes (DENV-1, DENV-2, DENV-3 ... See full document
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A ligand-binding pocket in the dengue virus envelope glycoprotein
... Mutations of residues that participate in the domain I兾II interface just described alter the threshold pH for fusion (Fig. 3). Most of them involve side chains in the -OG-binding pocket. We take this correlation as a ... See full document
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The Dengue virus in Nepal: gaps in diagnosis and surveillance
... Geographically, dengue was first reported in Hilly region in 2010, and there are no reports of dengue cases from Mountain region published as of today ...(Fig. 1). There is an increasing trend of ... See full document
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Structural modulations of the envelope gp120 glycoprotein of human immunodeficiency virus type 1 upon oligomerization and differential V3 loop epitope exposure of isolates displaying distinct tropism upon virion-soluble receptor binding.
... sucrose-purified virus stock was determined by the use of human polyclonal anti-HIV-1 sera (32, ...with 4% nonfat dry milk (Carnation) and Nonidet P-40 (1% ...virion envelope without ... See full document
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