[PDF] Top 20 Análise do funcionamento dos processos de treinamento de um órgão público federal
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Down-regulation of OGT promotes cisplatin resistance by inducing autophagy in ovarian cancer
... that OGT knockdown induces autolysosome formation, which promotes autophagic ...selective autophagy substrate and cargo receptor for degradation of ubiquitinated substrates by ...during ... See full document
408
Original Article Nrf2 induces cisplatin resistance through activation of autophagy in ovarian carcinoma
... that autophagy activation participates in chemoresistance in cancer cells, and down- regulation of autophagy sensitizes cancer cells to therapeutics ...and autophagy in ... See full document
76
<p>GRHL2 Upregulation Predicts a Poor Prognosis and Promotes the Resistance of Serous Ovarian Cancer to Cisplatin</p>
... cant down-regulation of many stan- dard carcinogenic pathways related to cell growth and proliferation, of which the down-regulation of ERK/ MAPK is the most signi fi ... See full document
6
HE4 promotes collateral resistance to cisplatin and paclitaxel in ovarian cancer cells
... to cisplatin and ...after cisplatin treatment, EGR1 is upregulated in SKOV3-NV cells, but not in SKOV3-C1 or SKOV3-C7 ...by cisplatin but not in SKOV3-C1 ...platinum resistance in pancreatic ... See full document
7
Original Article MCT1 promotes the cisplatin-resistance by antagonizing Fas in epithelial ovarian cancer
... of cisplatin-resistant ovarian cancer and its possible relationship with ...in cisplatin-resistant ovarian cancer tissue and A2780/CP cells compared with sensitive ovarian ... See full document
25
PKM2 Inhibitor Shikonin Overcomes the Cisplatin Resistance in Bladder Cancer by Inducing Necroptosis
... in cisplatin resistant bladder cancer cells and ...the cisplatin resistant in ...bladder cancer tissue samples, our results indicate that PKM2 is upregulated, making PKM2 a potential ... See full document
47
The oncogenic Golgi phosphoprotein 3 like overexpression is associated with cisplatin resistance in ovarian carcinoma and activating the NF-κB signaling pathway
... and promotes their survival, whereas inhibition of NF-κB signaling dramatically reduces the proliferation of oral squamous cell carcinoma ...and cisplatin-treated mesothelioma cells abolishes their ... See full document
10
Autophagy as an emerging therapy target for ovarian carcinoma
... inhibiting cancer cell growth, and ARHI is down-regulated in 60% of ovarian cancers ...of autophagy by suppressing PI3K/AKT and reducing the expression of Bcl-2 in ovarian cancer ... See full document
6
<p>Resveratrol As A Natural Regulator Of Autophagy For Prevention And Treatment Of Cancer</p>
... and autophagy are two self-destructive ...and autophagy is complex, and in some cases, autophagy forms a stress adaptation that protects cells from apoptosis, while in other cell environments, ... See full document
9
PRIMA-1 increases cisplatin sensitivity in chemoresistant ovarian cancer cells with p53 mutation: a requirement for Akt down-regulation
... activation promotes cell survival, suppresses apoptotic death and confers resistance of ovarian cancer cells to CDDP-induced apoptosis ...in ovarian cancer ...Akt promotes ... See full document
7
Mass spectrometry-based proteomics techniques and their application in ovarian cancer research
... normal ovarian tissues allowed for identification of OC-specific glycoproteins and glycosylation ...with cancer-specific glycosylation ...malignant ovarian cyst ...of cancer-associated gly- ... See full document
30
Translational Regulation Promotes Oxidative Stress Resistance in the Human Fungal Pathogen Cryptococcus neoformans
... upon treatment with cycloheximide, suggesting that ribosome association protects the mRNA from decay factors (Fig. 4B). Promoting translational suppression through glu- cose starvation in the gcn2Δ strain was able to ... See full document
110
Inhibition of autophagy promotes metastasis and glycolysis by inducing ROS in gastric cancer cells
... by autophagy inhibition in gastric ...of autophagy in gastric cancer cells promotes epithelial-mesenchymal transition (EMT) and metastasis, alters metabolic phenotype from mitochondrial ... See full document
392
<p>Akt/mTOR-Mediated Autophagy Confers Resistance To BET Inhibitor JQ1 In Ovarian Cancer</p>
... JQ1-induced autophagy in the resistant ...(B) Ovarian Cancer cell lines were incubated with increased concentrations of JQ1 for 48 h, and cell lysates were subjected to Western blotting using ... See full document
22
The role of epigenetics in resistance to cisplatin chemotherapy in lung cancer
... lung cancer (SCLC) and non-small cell lung cancer (NSCLC) [6], histological subtypes of NSCLC (squamous versus adenocarcinomatous) [7-9], as blood based (plasma or serum) biomarkers for the identification ... See full document
6
Essential role for acid sphingomyelinase-inhibited autophagy in melanoma response to cisplatin
... and autophagy was confirmed further in melanoma ...during autophagy activation is driven by inter-organellar micro-domains among which are mitochondria-associated endoplasmic reticulum membranes (MAMs) [17, ... See full document
151
ST6Gal-I sialyltransferase confers cisplatin resistance in ovarian tumor cells
... ST6Gal-I-mediated cisplatin-resistance may involve the differential sialylation of one or more drug ...Many cisplatin-resistant cell lines show reduced accumulation of cisplatin [47], pointing ... See full document
51
<p>NEAT1 Knockdown Suppresses the Cisplatin Resistance in Ovarian Cancer by Regulating miR-770-5p/PARP1 Axis</p>
... in cisplatin-resistant tis- sues (n=19) in comparison to that in sensitive group (n=18) (Figure ...in ovarian cancer tissues was negative correlated with the level of miR-770-5p ... See full document
18
Cyclin H predicts the poor prognosis and promotes the proliferation of ovarian cancer
... © The Author(s) 2020. This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you ... See full document
9
<p>Differential Expression And Effects Of Peroxiredoxin-6 On Drug Resistance And Cancer Stem Cell-Like Properties In Non-Small Cell Lung Cancer</p>
... However, cisplatin resis- tance to targeted therapy, which can result from multiple factors, is a major issue affecting the ef fi cacy of NSCLC ...in cisplatin resis- ...as cancer stem cells (CSCs), ... See full document
10
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