[PDF] Top 20 “Cuerpo a través”. Una experiencia de salud emocional en enseñanza del arte
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MOB1 Mediated Phospho-recognition in the Core Mammalian Hippo Pathway.
... Interestingly, the MST1 peptide sequences that interacted most tightly with MOB1B in our peptide arrays bore sequence similarity to the phosphorylation consensus we determined for the MST1 and MST2 kinases using a whole ... See full document
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The hippo signaling pathway: implications for heart regeneration and disease
... of Hippo signaling compo- nents between Drosophila and ...fly, mammalian Hippo signaling involves the activation of a conserved kinase cascade that ultimately phosphorylates the transcription ... See full document
51
PTEN lipid phosphatase inactivation links the hippo and PI3K/Akt pathways to induce gastric tumorigenesis
... The Hippo pathway is a highly conserved growth control signaling pathway identified in Drosophila in 1995 ...of Hippo has been found in lung adenocarcinoma, esophageal squamous cell carcinoma, ... See full document
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Spatial proteomic and phospho-proteomic organization in three prototypical cell migration modes
... signaling pathway cover- ...the phospho-proteomic dataset that are enriched in different fractions for different cell migration modes (Figure S3, Additional file 2); these are all not known to be relevant ... See full document
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Potential Role of Hippo Signaling Pathway in Gastric Cancer
... Gastric cancer is the fourth most regular perilous and second driving reason for death with more than 1.6 million new cases assessed in 2014 [1] [2]. The most well-known advancement of gastric tumor is gastritis ... See full document
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New insights into posttranslational modifications of Hippo pathway in carcinogenesis and therapeutics
... of Hippo signaling pathway has been linked to a variety of critical biological processes and human diseases, including organ growth control, stem cell func- tion, tissue regeneration and tumor ...the ... See full document
17
Hippo/YAP signaling pathway is involved in osteosarcoma chemoresistance
... the Hippo/YAP pathway in osteosarcoma chemoresistance, we successfully established stable YAP-overexpressing and YAP-knockdown MG63 cell lines by retrovirus and lentiviral ... See full document
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Deregulation Of The Hippo Pathway Suppresses Differentiation And Promotes Sarcomagenesis
... the Hippo signaling pathway is silenced in UPS, which allows for uncontrolled activation of YAP1 (Eisinger-Mathason et ...to Hippo pathway kinase deletion and epigenetic silencing of its ... See full document
14
The role of the Hippo pathway in human disease and tumorigenesis
... The Hippo signaling pathway has been demonstrated to play a central role in the regulation of tissue and organ size during ...of Hippo signaling leads to a concurrent combination of uncontrolled ... See full document
270
The Hippo pathway effectors TAZ and YAP in development, homeostasis and disease
... the Hippo pathway in intestinal development and repair, and what has emerged is a complex story surrounding the activity of ...Thus, Hippo pathway and YAP regulation of the intestinal ... See full document
12
WWC3 inhibits epithelial–mesenchymal transition of lung cancer by activating Hippo-YAP signaling
... the Hippo pathway, such as Wil- lin/FRMD6 and KIBRA, also contributes to inducing the EMT ...the Hippo path- way, increases expression of the EMT-related biomarkers, such as E-cadherin, ZO-1, and ... See full document
12
A Functional Polymorphism Mediated Disruption of EGR1/ADAM10 Pathway Confers the Risk of Sepsis Progression
... signaling pathway in the sample of sepsis patients and in vitro models that confirmed this, we evaluated whether EGR1 could serve as a therapeutic target for ...EGR1/ADAM10 pathway may be a potential ... See full document
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Statins induce insulin-degrading enzyme secretion from astrocytes via an autophagy-based unconventional secretory pathway
... increased functional IDE secretion in a time- and dose- dependent manner, and statin-induced IDE secretion was blocked by autophagy inhibition although IDE secretion at basal condition might be mediated by an ... See full document
5
Original Article Transcriptomic analysis of dracorhodin perchlorate intervention in wound healing in SD rats
... signaling pathway, malaria, and basal cell ...way, Hippo signaling pathway, and Cushing syn- drome, whereas downregulated genes were enriched in the myocardial adrenergic signal transduction, ... See full document
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Drosophila PI4KIIIalpha is required in follicle cells for oocyte polarization and Hippo signaling
... the Hippo pathway have been identified (Grusche et ...for Hippo pathway activity (McCartney et ...promotes Hippo activity (Baumgartner et ...the Hippo signaling pathway ... See full document
6
Mikhail V. Blagosklonny 1
... In 2003 it was proposed that activation of growth- promoting pathways should cause senescence, when the cell cycle is blocked [58]. In fact, mTOR converts reversible cell cycle arrest to cellular senescence ... See full document
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The Hippo Pathway Maintains the Equatorial Division Plane in the Ciliate Tetrahymena
... of Mob1 in Tetrahymena generates a cell division phenotype that closely resembles that of cdaI-1 (Tavares et ...and Mob1 are in the same pathway, and that cdaI-1 is a loss-of-function muta- ...of ... See full document
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Original Article miR-135b-5p regulates human mesenchymal stem cell osteogenic differentiation by facilitating the Hippo signaling pathway
... were obviously upregulated in hMSCs after miR-135b-5p transfection, whereas they were reduced by the miR-135b-5p inhibitor (P < 0.05, Figure 3A). Proliferative factors, including Oct-4, Nanog, CD44, SOX2, AXIN2, and ... See full document
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Case-oriented pathways analysis in pancreatic adenocarcinoma using data from a sleeping beauty transposon mutagenesis screen
... Background: Mutation studies of pancreatic ductal adenocarcinoma (PDA) have revealed complicated heterogeneous genomic landscapes of the disease. These studies cataloged a number of genes mutated at high frequencies, but ... See full document
5
Role of 5-HT7 receptors in the immune system in health and disease
... In mammalians, serotonin (5-HT) has critical roles in the central nervous system (CNS), including mood stability, pain tolerance, or sleep patterns. However, the vast majority of serotonin is produced by intestinal ... See full document
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