[PDF] Top 20 La democracia ante los avances de la tecnología : una perspectiva de Derecho constitucional
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Inflammatory but not apoptotic death of granulocytes citrullinates fibrinogen
... citrullinate fibrinogen specifically when undergoing inflammatory but not apoptotic death is that apoptotic death effectively sequesters PAD enzymes and deactivates them before ... See full document
39
Electrochemotherapy induces apoptotic death in melanoma metastases: a histologic and immunohistochemical investigation
... the inflammatory infiltrate, and initial tumor cell morphological changes were already detected 10 min after ...using apoptotic markers (TUNEL and caspase-3 staining), reached a climax 3 days after ... See full document
20
Apoptotic human cells inhibit migration of granulocytes via release of lactoferrin
... cell death that, in inflammatory terms, is quiet: apoptotic cells are rapidly phago- cytosed by their neighbors or by mononuclear phagocytes that are attracted by chemotactic factors such as ... See full document
78
Milk Fat Globule-EGF Factor VIII in Sepsis and Ischemia-Reperfusion Injury
... of inflammatory cytokines such as TNF-α, IL-1β, IL-6 and HMGB1, which act as a late proinflammatory cy- tokine by a substantial neuroendocrine and immune activation, plays a central role in the morbidity and ... See full document
67
Evaluating the discriminating capacity of cell death (apoptotic) biomarkers in sepsis
... these apoptotic biomarkers with both PCT and the APACHE II, and the known biology of apoptosis, we conjecture that apop- totic biomarkers reflect an important septic pathway non-collinear or not otherwise ... See full document
8
Effects of controlled diesel exhaust exposure on apoptosis and proliferation markers in bronchial epithelium – an in vivo bronchoscopy study on asthmatics, rhinitics and healthy subjects
... anti- apoptotic marker Bcl-2 (Dako, Ely, UK); the death recep- tor Fas (CD95) (TCS Biosciences ltd, Botolph Claydon, UK); the caspase cleavage product p85 PARP (Promega, Southampton, UK); and the cell ... See full document
17
Autophagy in cell death: an innocent convict?
... intact apoptotic machinery, autophagy is primarily a pro-survival rather than a pro- death ...cell death, the complex interplay between autophagy and apoptosis pathways, and the role of ... See full document
6
Decreased H2 Histamine Response of Granulocytes of Asthmatic Patients
... metiamide blocked histamine inhibition of lysosomal enzyme release and the increase in cyclic AMP. The effect was maximal at concentrations equimolar to those of histamine. The H1 antihistamine chlorpheniramine had no ... See full document
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Degradation products of fibrinogen by elastase like neutral protease from human granulocytes Characterization and effects on blood coagulation in vitro
... of fibrinogen towards the proteolytic action of the ...of fibrinogen and of plasmin-induced proteolysis products D and ...of fibrinogen by thrombin was inhibited according to the concentration of the ... See full document
27
Epigallocatechin-3-gallate suppresses cell proliferation and promotes apoptosis and autophagy in oral cancer SSC-4 cells
... Abstract: Epigallocatechin-3-gallate (EGCG) is the major bioactive component of green tea. Our experimental data indicated that EGCG treatment suppresses cell proliferation of SSC-4 human oral squamous cell carcinoma ... See full document
32
Beraprost Sodium, a Prostaglandin I2 Analogue, Protects Against Advanced Glycation End Products-induced Injury in Cultured Retinal Pericytes
... induced apoptotic cell death in pericytes through interaction with RAGE proteins (8,9), anti-apoptotic effects of beraprost sodium observed here could be, at least in part, as- cribed to inhibition ... See full document
10
Quantification of Chondrocyte Apoptosis in Mechanically Impacted Articular Cartilage
... shear. Apoptotic cells and live cells were counted and the percentage of apoptotic cells was determined at all the radial positions (r = 0, ± r/2, ± r, ± 2r) through the depth of the ... See full document
26
Anti-tumor effects of a recombinant anti-prostate specific membrane antigen immunotoxin against prostate cancer cells
... Wild-type caspase-3 consists of an NH2-terminal pro- domain, a large subunit, and a small subunit. However, active caspase-3, which is constructed with the reverse order of the subunits [30], can induce apoptosis of ... See full document
9
Effects of quercetin nanoliposomes on C6 glioma cells through induction of type III programmed cell death
... cell death which is distinct from apoptosis and autophagy, induces necrotic but not apoptotic cell death, and is associated with loss of the mitochondrial membrane potential ( ∆Ψ m) and induction of ... See full document
23
Toll-like receptor 2 signaling is a mediator of apoptosis in herpes simplex virus-infected microglia
... of apoptotic genes, we performed microarray analyses using mouse-specific apoptosis ...the apoptotic genes were markedly different between wild-type and in TLR2 -/- microglial ... See full document
8
Oridonin Enhances Radiation-Induced Cell Death by Promoting DNA Damage in Non-Small Cell Lung Cancer Cells
... oridonin and radiation greatly enhanced ROS production, DNA damage, and apoptotic cell death of 225. H460 cells[r] ... See full document
20
Lgr4 mediated Wnt/β catenin signaling in peritubular myoid cells is essential for spermatogenesis
... Numerous germ cells undergoing apoptotic cell death were observed in each seminiferous tubule in Lgr4-deficient mice, whereas in WT mice few apoptotic cells were observed in individual t[r] ... See full document
8
Docosahexaenoic Acid Induces Cell Death through Downregulation of Hedgehog Signaling via Surt6 Activation in Human EGFR Mutant Non-Small Cell Lung Cancer
... stable PC9 cells (f-PC9) (Figure 5). Therefore, our findings strongly suggest that ω3-PUFAs may modulate SIRT6 and Hh signaling molecules in EGFR mutant NSCLC cells. However, the mechanism by which SIRT6 activation ... See full document
15
Cytokine patterns in nasal secretion of non-atopic patients distinguish between chronic rhinosinusitis with or without nasal polys
... not only different phenotypes like CRS with or without nasal polyps but also consisting of diverse endotypes. New therapeutic approaches with biologic agents are cur- rently in development [17]. These new approaches ... See full document
29
Involvement of Pro-Apoptotic and Pro-Autophagic Proteins in Granulosa Cell Death
... Our morphological and immunohistochemicalobserva- tions were further strengthened by biochemical analyses and molecular assays, which showed that the mRNAs of the caspase-3 and LC3 areexpressed in isolated granulosa cell ... See full document
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