[PDF] Top 20 Dengue, Chikunguña y Zika en Colombia 2015-2016
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<p>Gephyrin suppresses lung squamous cell carcinoma development by reducing mTOR pathway activation</p>
... of gephyrin in LUSC cell proliferation, the gephyrin cDNAwas cloned into the pLV vector to establish stable overexpression of gephyrin human LUSC cell lines H520 and ...the lung ... See full document
5
Immunohistochemical evaluation of p-mTOR (Phosphorylated Mammalian Target of Rapamycin) in oral squamous cell carcinoma
... of activation of Akt in various stages of Squamous Cell C arcinoma development in mice and in clinical samples from HNSCC ...Akt activation correlates closely with the progression of ... See full document
114
<p>Silencing of LINC01116 suppresses the development of oral squamous cell carcinoma by up-regulating microRNA-136 to inhibit FN1</p>
... the development and pro- gression of multiple types of cancers, including prostate, bladder, and kidney ...suppressed cell proliferation in prostate ...inhibit cell proliferation, migration, and ... See full document
119
<p>Genipin Induces Autophagy and Suppresses Cell Growth of Oral Squamous Cell Carcinoma via PI3K/AKT/MTOR Pathway</p>
... and mTOR in a concentration- dependent manner, indicating that the PI3K/Akt/mTOR sig- naling pathway was ...of p-PI3K, p-AKT, and p-mTOR, as well as the protein levels of ... See full document
11
<p>DUSP9 Suppresses Proliferation and Migration of Clear Cell Renal Cell Carcinoma via the mTOR Pathway</p>
... of cell growth, proliferation, and survival. 26 mTOR activation is closely linked to the activation of mTORC1, 27 and the available mTOR inhibitors mainly act on ...shown mTOR to ... See full document
5
<p>SASH1 Suppresses the Proliferation and Invasion of Human Skin Squamous Cell Carcinoma Cells via Inhibiting Akt Cascade</p>
... the development and progression of cSCC. 22 Overexpression of p-Akt is found in the tissues of skin cancer, and high expression of p-Akt is associated with the invasion and metastasis of ...elevated ... See full document
15
<p>USP13 serves as a tumor suppressor via the PTEN/AKT pathway in oral squamous cell carcinoma</p>
... (#9552, Cell Signaling Technology, Danvers, MA, USA), p-AKT (#9271, Cell Signaling Technology), AKT (#9272, Cell Signaling Technology), and glyceraldehyde- 3-phosphate dehydrogenase (#5174, ... See full document
18
Soluble Toll-like receptor 4 is a potential serum biomarker in non-small cell lung cancer
... Lung cancer is one of the most frequently diagnosed cancers and the leading cause of cancer death worldwide with high metastasis and recurrence rates [1, 2]. About 87% of lung cancer is classified as ... See full document
46
<p>Cryptotanshinone inhibits esophageal squamous-cell carcinoma in vitro and in vivo through the suppression of STAT3 activation</p>
... The cell viability ratio was calculated by the following formula: Cell viability (%) = (Average absorbance of treated group/ Average absorbance of control group) × ... See full document
19
<p>The Role of β-Arrestin1 in Esophageal Squamous Cell Carcinoma</p>
... ESCC is one of the most fatal malignant tumors in diges- tive system. Although researches in the early diagnosis of ESCC, as well as surgical treatment, local and systemic adjuvant therapy and other aspects have made a ... See full document
5
<p>High ACTN1 Is Associated with Poor Prognosis, and ACTN1 Silencing Suppresses Cell Proliferation and Metastasis in Oral Squamous Cell Carcinoma</p>
... heart, lung, liver, kidney, or other systemic diseases; 4) other tumors or mental disorder; 5) having diseases of the immune system or HIV infection; and 6) have received anticancer treat- ment 3 months before the ... See full document
22
Combating head and neck cancer metastases by targeting Src using multifunctional nanoparticle-based saracatinib
... HNSCC cell MET induced by Src inactiva- tion ...three cell lines in the presence and absence of Src inhibitors, excluding their common func- tions in drug-induced diminishment of EMT traits in ... See full document
5
Squamous cell carcinomas of the lung and of the head and neck: new insights on molecular characterization
... 17 cell lines including all four LSCC ...of cell lines responded to five of the 24 drugs (Panobinostat, 17-AAG, Irinotecan, Topotecan, and Paclitaxel) and the secretive subtype was significantly less ... See full document
101
<p>MLL3 promotes the senescence of esophageal squamous cell carcinoma</p>
... Next, we knocked down MLL3 expression in Eca109 and Caes17 cells (Figure 3A). Downregulation of MLL3 promoted ESCC cell growth as revealed by MTT assay (Figure 3B). Moreover, reduced MLL3 expression enhanced ... See full document
11
<p>Silenced Myeloblastosis Protein Suppresses Oral Tongue Squamous Cell Carcinoma via the microRNA-130a/Cylindromatosis Axis</p>
... CYLD downregulation induced by miR-130b brought about glioma cell development and invasion. 36 In dermal fi brosis malignancies, miR-130a augmented myo fi broblast transformation, collagen secretion and ... See full document
6
<p>Piceatannol Suppresses the Proliferation and Induced Apoptosis of Osteosarcoma Cells Through PI3K/AKT/mTOR Pathway</p>
... PI3K/AKT/mTOR pathway inhibitor (LY294002), or pathway activator (740Y-P) plus ...and cell cycle of treated cells were determined by MTT test, colony formation assay or a fl ow ... See full document
5
Sites of metastasis and overall survival in esophageal cancer: a population-based study
... 0.858, p = ...0.844–1.569, p = 0.374), brain (HR 0.776, 95% CI 0.191–3.155, p = ...and lung (HR 0.891, 95% CI 0.684–1.161, p = ...1.024–1.462, p = ...0.570–0.768, p < ... See full document
9
Prognostic implications of the phosphatidylinositol 3-kinase/Akt signaling pathway in oral squamous cell carcinoma: overexpression of p-mTOR indicates an adverse prognosis
... PI3K/AKT pathway is frequently overactive in various tumors, which triggers a cascade of responses that drive tumor progression, including aberrant cell growth, proliferation, increased cell ... See full document
38
Curcumin suppresses the progression of laryngeal squamous cell carcinoma through the upregulation of miR-145 and inhibition of the PI3K/Akt/mTOR pathway
... a cell lysis buffer (Beyotime, Shanghai, People’s Republic of China) containing protease inhibitor phenylmethylsulfonyl fluoride (PMSF) ...(Beyotime). Cell lysates containing equal amounts of protein were ... See full document
80
<p>Construction and validation of a seven-microRNA signature as a prognostic tool for lung squamous cell carcinoma</p>
... Materials and methods: With the use of mature miR expression pro fi les downloaded from The Cancer Genome Atlas database, we identi fi ed differentially expressed miRs between LUSC and matched healthy lung tissue. ... See full document
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