[PDF] Top 20 Economía y política monetaria
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Using peptide aptamers to analyse the proteome
... More than 20 TrxA peptide aptamers have since been identified in Single-step selections against numerous protein targets; one aptamer resulted from a round of mutagenesis[r] ... See full document
9
Improved proteome coverage by using iTRAQ labelling and peptide OFFGEL fractionation
... Combining results of all experiments, we end up with 947 proteins (Additional file1) identified with at least 2 pep- tides and 6119 unique peptides. 380 detected proteins have at least 5 or more unique peptides ... See full document
7
Longitudinal Analysis of the Human Antibody Response to Chikungunya Virus Infection: Implications for Serodiagnosis and Vaccine Development
... Structural localization of the antigenic regions recognized by human antibodies. Epitope-containing sequences were subse- quently mapped onto the available three-dimensional (3D) crystal structures of the E3 and E2 ... See full document
177
Inhibition of Human Cytomegalovirus Replication via Peptide Aptamers Directed against the Nonconventional Nuclear Localization Signal of the Essential Viral Replication Factor pUL84
... employed peptide aptamer technology and isolated several peptide aptamers from a randomized peptide expression library that specifically bind with high affinity to the uncon- ventional pUL84 ... See full document
142
Differential analysis of quantitative proteome and acetyl-proteome profiling between premenopausal and postmenopausal ovarian tissues
... Health Organization (WHO), an estimated one billion women will be over 60 year-old by the year 2050, sug- gesting that more than one billion women will be at the postmenopausal status, which is becoming a world- wide ... See full document
17
The Applications of Aptamers in the Field Of Therapeutics
... where aptamers can be applied, due to their ability to detect cell-specific markers within complex systems that are devoid of specified target ...Moreover, aptamers, which are highly specific for cancer ... See full document
14
GE11 peptide-conjugated nanoliposomes to enhance the combinational therapeutic efficacy of docetaxel and siRNA in laryngeal cancers
... GE11 peptide-conjugated liposomes that enhanced the combined therapeutic efficacies of DTX and ABCG2– siRNA in laryngeal ...GE11 peptide- conjugated liposomes enhanced anti-tumor and apoptotic effects ... See full document
11
Analyse the Stress Concentration Effect of a ...
... Narayanan and Chow (20) developed design charts based on ultimate capacity of uniaxially compressed perforated plates with square and circular openings. Yettram and Brow (21) studied the stability behaviour of flat ... See full document
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APTAMER: A MIRACLE TOOL FOR TARGETED DRUG DELIVERY
... enrichment). Aptamers are different from antibodies, Aptamers are having novel properties, such as highly selective and specific target recognition and ...binding. Aptamers have advantages on ... See full document
16
Gefitinib loaded DSPE PEG2000 nanomicelles with CD133 aptamers target lung cancer stem cells
... as aptamers or antibodies have attracted extensive attentions, since they could improve the targeting efficacy of chemother- apy drugs [13 – ...[15]. Aptamers — o- ligonucleic acids — have advantages ... See full document
21
Characterization of In Vitro Selected RNA Aptamers for the RB69 RegA Translational Repressor Protein and Optimization of in vitro Selection Utilizing Complex Targets
... Nucleic acid selections are highly successful inside the laboratory, however, this success quickly coorelates into failure if the efficacy of the selected molecules is poor due to quick degradation, in real world ... See full document
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Poly(lactic-co-glycolic acid) nanoparticles conjugated with CD133 aptamers for targeted salinomycin delivery to CD133<sup>+</sup> osteosarcoma cancer stem cells
... PLGA (17 k)-PEG (3 k)-COOH was bought from PolySciTech (Akina, Inc., West Lafayette, IN, USA). Salinomycin, cou- marin 6, 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide (EDC), and N-hydroxysuccinimide (NHS) were purchased ... See full document
9
Inhibition of the foot-and-mouth disease virus subgenomic replicon by RNA aptamers.
... of aptamers in a topical/localized ...for aptamers in diagnostics, alongside more conventional antibodies (reviewed by Brody & Gold, ...RNA aptamers described here, together with aptamers ... See full document
8
Modified nucleosides and oligonucleotides as ligands for asymmetric reactions
... Reetz and co-workes have used a Darwinistic approach to genetically modify proteins to better fit their enantioselective reactions and to be more stable in the presence of non-natural substrates. This method is called ... See full document
10
Generating Cell Targeting Aptamers for Nanotheranostics Using Cell-SELEX
... strands, aptamers, drug-loading sites and dyes can be easily integrated into the size-tunable and stable structure by rational design of the circular DNA template; NFs are ideal candidates for a variety of ... See full document
126
Aptamers: Diagnostic and Therapeutic Applications
... Correspondingly, aptamers have a unique niche relative to other oligonucleotide ...[30]. Aptamers can theoretically be used therapeutically in any disease for which extracellular blockade of protein-protein ... See full document
14
Aptamers in the Therapeutics and Diagnostics Pipelines
... toxin is highly toxic even at low doses, thus the maximum allowed levels of this toxin as set by the European Union are 5, 2 and 0.5 ppb for cereals, wine, and baby food respectively. Therefore, highly sensitive ... See full document
6
Aptamers—A Promising Approach for Sensing of Biothreats Using Different Bioinformatics Tools
... for early detection and monitoring purpose [6]. The trans- ducer will convert any physicochemical changes taking place in its proximity into visible signals [7,8]. These are based on electrochemical, optical, ... See full document
59
Whole virus detection using aptamers and paper-based sensor potentiometry
... mechanism using modified “clean” samples and progresses toward more realistic samples in real ...virus using a paper-based potentiometric device that to the best of our knowledge was not done ...a) ... See full document
14
Developing aptamers into therapeutics
... cost. Aptamers targeting conditions that meet some or all of these criteria have made the most progress towards clinical ...which aptamers have progressed to animal and/or human ... See full document
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