[PDF] Top 20 Estudio de los marcadores de severidad en la sepsis grave y shock séptico
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Association of mRNA expression of TP53 and the TP53 codon 72 Arg/Pro gene polymorphism with colorectal cancer risk in Asian population: a bioinformatics analysis and meta-analysis
... the mRNA expression level of TP53 in 212 sequenced ...including TP53 gene and the 50 most frequently altered neighbor genes (50/222), and the top three (APAF1, APC, ASF1A) are marked ... See full document
117
Polymorphisms of TP53 codon 72 with breast carcinoma risk: evidence from 12226 cases and 10782 controls
... example, Arg variant might induce cell apoptosis and suppress transformation more efficiently than Pro variant do, which may be due to the ability of the Arg variant to localize in mitochondria that ... See full document
14
Association of p53 codon 72 Arg>Pro polymorphism and risk of cancer in Iranian population: A systematic review and meta-analysis
... this meta-analysis revealed no association between variant allele of p53 c 72 G>C polymorphism with an increased or decreased cancer ...p53 Codon 72 G>C ... See full document
5
No association of TP53 codon 72 and intron 3 16-bp duplication polymorphisms with breast cancer risk in Chinese Han women: new evidence from a population-based case–control investigation
... Breast cancer is the world’s most common and deadly cancer in ...suppressor gene TP53, which is located on ...breast cancer susceptibility genes, as the p53 protein plays an important ... See full document
15
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... Arg72Pro polymorphism (rs1042522) at codon 72 in exon 4 of the TP53 gene have reported an association of the Arg allele with increased risks for colorectal, breast ... See full document
100
The CXCL12 rs1801157 polymorphism and risk of colorectal cancer: a meta-analysis
... this meta-analysis although the abovementioned results and analysis need to be further studied? All meta-analyses about CXCL12 poly- morphism and the risk of malignancies were fully ... See full document
8
TNFAIP3 gene rs10499194, rs13207033 polymorphisms decrease the risk of rheumatoid arthritis
... their meta-analysis [25] suggested that rs10499194 polymorphism was weakly associated with an increased risk of RA among Asian populations, while no association was observed ... See full document
84
Association of VDR gene TaqI polymorphism with the susceptibility to prostate cancer in Asian population evaluated by an updated systematic meta-analysis
... Moreover, there are several limitations of this meta- analysis. 1) Observational studies are susceptible to a wide variety of biases, such as genotyping errors, allelic hetero- geneity, and selection bias; ... See full document
29
Association of lncRNA H19 rs217727 polymorphism and cancer risk in the Chinese population: a meta-analysis
... its expression and function as well [13, ...rs217727 polymorphism has been shown to be associated with susceptibility to gastric cancer, breast cancer, and bladder cancer in the Chinese ... See full document
7
Evidence of Interaction between PTPN22 and p53 codon 72 Polymorphisms on Susceptibility to Immune Related Diseases
... Appropriate studies on immunological parameter in presence of only one and in presence of both risk factors could contribute to elucidate the mechanism of interaction. From a practical point of view the ... See full document
15
Detection of human papillomavirus DNA and p53 codon 72 polymorphism in prostate carcinomas of patients from Argentina
... p53 polymorphism at codon 72 (Arg, Pro or Arg/Pro) in the leukocyte and tumor DNA from 39 patients with prostate carcinomas and 48 patients with prostate hyperplasias by ... See full document
427
TP53 codon 72 polymorphism may predict early tumour progression in paediatric pilocytic astrocytoma
... bivariate analysis or clinically important variables were subsequently included in the multivariate ...p53 codon 72 SNP (Arg/Arg vs. Arg/Pro or ... See full document
181
Öner-Ziegler, Meryem Gülfem (2019): Genetic analysis of Mir34a in mouse models of colorectal cancer. Dissertation, LMU München: Medizinische Fakultät
... von TP53 (durch Mutation) und von MIR34A (durch CpG ...sowohl TP53, als auch MIR-34A inaktiviert ...diese Gene in einem Modell für sporadisches Kolorektales Karzinom simultan deletiert und die frühe ... See full document
106
Methylation of MGMT and ADAMTS14 in normal colon mucosa: biomarkers of a field defect for cancerization preferentially targeting elder African-Americans
... and TP53 in colorectal cancer (CRC). We tested the association of MGMT methylation with G > A mutations in KRAS and TP53 in 261 ...significant association of MGMT methylation ... See full document
91
Analysis of Polymorphism rs1042522 in TP53 Gene in the Mothers of Twins and of Singletons: A Population-Based Study in Rio Grande do Sul, Brazil
... of polymorphism rs1042522 in the TP53 gene was more frequent in the mothers of twins than in the mothers of singletons in a small village in South ...a population-based, observational ... See full document
45
Codon 72 Polymorphism of p53 Gene and Hematologic Manifestations in Patients with Systemic Lupus Erythematosus
... Pro R: CGT GCA AGT CAC AGA CTT ------------------------------------------------- PCR products were analyzed using 2% agarose gel electrophoresis, with ethidium bromide staining by UV transilluminator devices. PCR ... See full document
9
Exploratory analyses of consensus molecular subtype-dependent associations of TP53 mutations with immunomodulation and prognosis in colorectal cancer
... Results TP53 mutations were found in 60% of the CRCs. However, gene set enrichment analyses indicated that their transcriptional consequences varied among the CMSs and were most pronounced in CMS1-immune ... See full document
60
Review Article p53 codon 72 polymorphism is associated with human papillomavirus-related esophageal cancer risk: a meta-analysis
... [19] Canova C, Hashibe M, Simonato L, Nelis M, Metspalu A, Lagiou P, Trichopoulos D, Ahrens W, Pigeot I, Merletti F, Richiardi L, Talamini R, Barzan L, Macfarlane GJ, Macfarlane TV, Holcatova I, Bencko V, Benhamou S, ... See full document
115
Tooth loss and risk of colorectal cancer: a dose–response meta-analysis of prospective cohort studies
... significant association between tooth loss and colorectal cancer (OR ...regression analysis, and the summary relative risk (RR) of colorectal cancer for an increase of ... See full document
9
Association between <em>TP53</em> gene Arg72Pro polymorphism and Wilms’ tumor risk in a Chinese population
... childhood cancer worldwide. TP53 is a critical tumor suppressor gene, which encodes a 53 kDa protein, ...against cancer by regulating cell cycle and apoptosis and maintaining DNA ...integrity. ... See full document
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