[PDF] Top 20 Evaluacin de la cultura de seguridad del paciente en un quirfano
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An in silico based characterization and analysis of Human matrix metalloproteinases (MMPs)
... all human MMPs would greatly aid researchers to identify the MMPs of interest relevant to their respective working ...comparative characterization studies for other large protein families, using the ... See full document
22
Targeting matrix metalloproteinases with novel diazepine substituted cinnamic acid derivatives: design, synthesis, in vitro and in silico studies
... (m-RNA analysis) method by measuring the expression levels of MMP-2 and ...cancer. Based on the results, it can be concluded that compound 16 may be taken as a lead compound for the discovery of new drug ... See full document
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Subtractive genome analysis for in silico identification and characterization of novel drug targets in c trachomatis strain d/uw 3/cx
... Studies based on subtractive genomics approach could facilitate the selection, processing and specific drugs against various ...study based on complete 3/Cx (ocular-urogenital pathogen of homologous to ... See full document
28
Matrix metalloproteinases in pancreatitis: current insights
... MT-MMPs are membrane associated proteases that majorly result in recruitment of receptors to the site of injury. There are six members that belong to this subgroup. Four of them (MMP14, MMP15, MMP16, and MMP24) are type ... See full document
13
Matrix metalloproteinases in cystic fibrosis: pathophysiologic and therapeutic perspectives
... regenerating human CF epithelium has been developed in which human CF epithelial cells are seeded onto denuded rat tracheas which were then transplanted into the subcutaneous space of nude ... See full document
25
Short Link N promotes disc repair in a rabbit model of disc degeneration
... extracellular matrix, and its repair requires the production of an extracellular matrix with a high proteoglycan-to- collagen ratio characteristic of a nucleus pulposus (NP)-like phenotype in ... See full document
9
Original Article Matrine inhibits IL-1β-induced expression of matrix metalloproteinases by suppressing the activation of MAPK and NF-κB in human chondrocytes in vitro
... extracellular matrix macromolecules and decreased expression of chondrocyte pro- tein and resulted in severe joint pain, loss of movement, and progressive irreversible dys- function ...that matrix metal- ... See full document
15
Matrix metalloproteinases and their inhibitors in cardiovascular pathologies: current knowledge and clinical potential
... Abstract: Matrix metalloproteinases (MMPs) constitute a family of endopeptidases that harbor matrix-degrading potential, but also modulate the proliferation, migration, and apoptosis of resident ... See full document
19
Matrix metalloproteinases and their inhibitors in the gastrointestinal cancers: current knowledge and clinical potential
... SNP analysis also offers the potential for a better diagnosis of various diseases and prediction of clinical outcome and therapeutic efficiency in several ... See full document
22
Expression of matrix metalloproteinases and components of the endocannabinoid system in the knee joint are associated with biphasic pain progression in a rat model of osteoarthritis
... Joint tissue samples consisted of meniscus and articular cartilage of the tibia and femur (synovium and bone were discarded; isolation of all specimens was performed by one researcher only). The specimens were isolated ... See full document
9
In silico characterization of human cytochrome P450 monooxygenases
... of human CYPs retrieved from UniprotKB have been characterized for various physio- chemical properties, homology search, motif and super family search and phylogenetic ...Physicochemical analysis showed ... See full document
9
MMP16 is a marker of poor prognosis in gastric cancer promoting proliferation and invasion
... tumor blood vessels and can degrade the extracellular matrix (ECM), [8]. MMPs family share a relative large percentage of common structural and functional areas, but differ in their substrate specificities [9]. ... See full document
10
Development and validation of an HPLC method for analysis of etoricoxib in human plasma
... An aliquot quantity of 1 ml of plasma spiked with etoricoxib raw drug was taken in a stoppered test tube. To this 10 µl of 150 µg/ml of internal standard (valdecoxib in acetonitrile) was added and mixed well. Saturated ... See full document
8
Expression of CD147 and matrix metalloproteinase 11 in colorectal cancer and their relationship to clinicopathological features
... lular matrix metalloproteinase inducer (EMMPRIN), is a member of the immunoglobulin superfamily of adhesion ...secrete matrix metalloproteinases ... See full document
13
In Silico Analysis of the Protein Structure of Tumor Suppressor Genes in Humans
... Abstract:- Tumor suppressor genes encode for proteins that are involved in inhibition of cell proliferation, induction of apoptosis, DNA damage repair and inhibition of metastasis and these are crucial to normal cell ... See full document
25
In silico analysis of histone H3 gene expression during human brain development
... in silico study, we re-evaluated genomic organization of the human H3 gene family and expression of these genes in the human brain, utilizing public RNA-based sequence datasets for the ... See full document
20
Aggrecan is degraded by matrix metalloproteinases in human arthritis Evidence that matrix metalloproteinase and aggrecanase activities can be independent
... Materials. Cysteine proteinase inhibitor E-64, pepstatin, and 2,2 9 Azino-di-[3 ethylbenzthiazoline sulfonate] (ABTS) were from Boehringer Mannheim (Mannheim, Germany). Keratanase ( Pseudo- monas sp. ) (EC 3.2.1.103), ... See full document
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In silico-based identification of human α-enolase inhibitors to block cancer cell growth metabolically
... property analysis, the 10 chemical structures are predicted to have good abil- ity to penetrate the blood–brain barrier (BBB + ), which is important when the lesion is within the ...The analysis shows that ... See full document
30
The Expression of Matrix Metalloproteinases and Tissue Inhibitors of Metalloproteinases in Idiopathic Interstitisal Pneumonia
... unclear, matrix metalloproteinases (MMP) and tissue inhibitors of matalloproteinases (TIMP) are known to be important factors that affect the progress of IPF ... See full document
14
Matrix Metalloproteinases and Tissue Inhibitors of Matrix Metalloproteinases as Plasma Indicators of Bovine Cystic Ovarian Disease
... A total of 65 lactating Holstein cows were used in this study and were housed at a cooperating dairy in Coburg, Oregon. This dairy had approximately 3000 cows with 1500 milking. Cows were provided with free-choice water ... See full document
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