[PDF] Top 20 Evaluación de extractos vegetales como agentes antifúngicos para pinturas
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Rituximab for the treatment of patients with chronic lymphocytic leukemia
... Since patients with elevated serum beta-2 microglobulin achieved lower CR rate and shorter PFS when treated with frontline chemoimmunotherapy (FCR), for this subgroup of high-risk patients a trial to ... See full document
10
Differences in Treatment Patterns and Health Care Costs among Non Hodgkin’s Lymphoma and Chronic Lymphocytic Leukemia Patients Receiving Rituximab in the Hospital Outpatient Setting versus the Office/Clinic Setting
... of rituximab infusions in the hospit- al outpatient setting was related to specific comorbidity or performance status, could not be ...possible patients with more severe disease were more likely to receive ... See full document
66
Critical appraisal of the role of rituximab in the treatment of patients with previously untreated or treated chronic lymphocytic leukemia (CLL)
... 74 patients who completed treatment, 24% achieved CR, ...In patients with 17p del, 44% responded to cyclophosphamide, fludarabine, alemtuzumab, and rituximab (CFAR), while 19% of ... See full document
5
Cost-effectiveness of adding rituximab to fludarabine and cyclophosphamide for treatment of chronic lymphocytic leukemia in Ukraine
... adding rituximab to fludarabine and cyclophosphamide scheme (FCR versus FC) for treatment-naïve and refractory/relapsed Ukrainian patients with chronic lymphocytic ...assess ... See full document
78
Role of rituximab in first-line treatment of chronic lymphocytic leukemia
... CLL patients to receive six monthly cycles of FC or FCR, using the same dosing regimen as the MDACC ...of patients were Binet stage B or ...761 patients evaluable for response, 790 patients ... See full document
13
Profile of obinutuzumab for the treatment of patients with previously untreated chronic lymphocytic leukemia
... Abstract: Chronic lymphocytic leukemia (CLL) is a hematologic malignancy derived from a clonal population of mature B-lymphocytes characterized by relatively low CD20 antigen ...of patients ... See full document
16
Clinical role of obinutuzumab in the treatment of naive patients with chronic lymphocytic leukemia
... to rituximab, an agent commonly used in the treatment of ...to treatment discontinuation in 7% of patients in the G-CLB arm compared to ,1% in the R-CLB ...these patients were ... See full document
60
Profile of venetoclax and its potential in the context of treatment of relapsed or refractory chronic lymphocytic leukemia
... the patients received 400 mg venetoclax as con- tinuous therapy until disease progression, unacceptable side effects, or other reasons for discontinuation, like subsequent allogeneic stem-cell transplantation, ... See full document
16
Targeted treatment for chronic lymphocytic leukemia
... for rituximab, for which combination chemotherapy strategies have clearly improved disease responsiveness and advantage in survival outcome of patients with ... See full document
11
Fludarabine in the treatment of chronic lymphocytic leukemia: a review
... 100 patients (90 B-CLL, 7 B-cell prolymphocytic leukemia, 3 Waldenström macroglobulinemia) using fl uorescence in situ hybridization (FISH) with a genomic p53 DNA ...100 patients exhibited a ... See full document
21
Recent Achievements in the Treatment of Chronic Lymphocytic Leukemia
... Current treatment approaches in chronic lymphocytic leukemia include alkylating agents, purine nucleoside analogs and monoclonal antibodies ...current treatment options and novel ... See full document
29
Ibrutinib and novel BTK inhibitors in clinical development
... revolutionized treatment options and clinical outcomes in cancer pa- tients ...instance, rituximab, a first-in-class chimeric monoclonal antibody (MoAb) targeting CD 20 molecule, has had clear impact on ... See full document
5
DNA methylation profiles in chronic lymphocytic leukemia patients treated with chemoimmunotherapy
... Next, we examined potential associations of epigenetic evolution regarding the EB and RC with particular bio- logical characteristics of the malignant clones. Consider- ing that the vast majority of cases (29/34, 85.2%) ... See full document
5
Role of ofatumumab in treatment of chronic lymphocytic leukemia
... than rituximab, which may lead to a longer duration of treatment response and could potentially result in a smaller dose being ...following treatment with ... See full document
9
17p deletion strongly influences rituximab elimination in chronic lymphocytic leukemia
... Chronic lymphocytic leukemia (CLL) is the most common type of leukemia and the anti-CD20 monoclonal antibody, rituximab, represents the therapeutic gold standard for more than 2 decades ... See full document
128
A Double-Blind, Randomized Comparison Study between Zytux™ vs MabThera® in Treatment of CLL with FCR Regimen: Non-Inferiority Clinical Trial
... including rituximab (that binds to CD20 antigen on B-cell surface) are among the most effective treatment options 9,10 ...in patients treated with Rituximab, Fludarabine and Cyclophosphamide ... See full document
9
Clinical utility and patient considerations in the use of ofatumumab in chronic lymphocytic leukemia
... CLL patients are represented by subjects older than 65 years, there is still a significant lack of treatment options for this ...overcome rituximab-based combination in terms of response quality and ... See full document
84
The spectrum of use of rituximab in chronic lymphocytic leukemia
... antibody, rituximab, has considerably improved therapeutic outcome in B-cell chronic lymphocytic ...leukemia. Rituximab has limited clinical activity when used as a single ...pretreated ... See full document
19
Role of bendamustine in the treatment of chronic lymphocytic leukemia
... of patients with chronic lymphocytic leukemia (CLL) include an enhanced ability to make an accurate diagnosis and defi ne clinically meaningful prognostic groups, while improving outcome ... See full document
5
B cell receptor pathway in chronic lymphocytic leukemia: specific role of CC-292
... Abstract: Chronic lymphocytic leukemia (CLL) is the most common adult ...current treatment paradigm involves the use of chemoimmunotherapy, when patients develop an indication for ...of ... See full document
7
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