[PDF] Top 20 Limite e derivada: Uma análise da produção escrita dos alunos
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Candidate genetic modifiers for breast and ovarian cancer risk in BRCA1 and BRCA2 mutation carriers.
... Hereditary Cancer Research Registry (COH-CCGCRN) is supported in part by Award Number RC4CA153828 (PI: ...National Cancer Institute and the Office of the Director, National Institutes of ...by Cancer ... See full document
21
Evaluation of Polygenic Risk Scores for Breast and Ovarian Cancer Risk Prediction in BRCA1 and BRCA2 Mutation Carriers.
... Hereditary Breast and Ovarian Cancer Research Group Netherlands (HEBON) consists of the following Collaborating Centers: Coordinating c\Center: Netherlands Cancer Institute, Amsterdam, NL: ... See full document
38
Mendelian randomisation study of height and body mass index as modifiers of ovarian cancer risk in 22,588 BRCA1 and BRCA2 mutation carriers.
... of Cancer Research (AIRC) [IG 2013 ...and Cancer Research Initiatives ...in Breast Cancer (CA125183), R01 CA142996, 1U01CA161032, P20CA233307, American Cancer Society ... See full document
27
Founder populations and their uses for breast cancer genetics
... unaffected mutation carrier is identified, the question becomes what is the likelihood that she will develop cancer by a given age (age-specific ...of cancer are ...develop breast ... See full document
23
Fine-Scale Mapping at 9p22.2 Identifies Candidate Causal Variants That Modify Ovarian Cancer Risk in BRCA1 and BRCA2 Mutation Carriers.
... Hereditary Cancer Program, IDIBELL (Bellvitge Biomedical Research Institute), Catalan Institute of Oncology, Gran Via de l'Hospitalet, 199 – 203, 08908 L'Hospitalet, Barcelona, Spain, 36 Molecular Diagnostics ... See full document
8
Male breast cancer in BRCA1 and BRCA2 mutation carriers: pathology data from the Consortium of Investigators of Modifiers of BRCA1/2
... Hereditary Breast and Ovarian Cancer (GC-HBOC) is supported by the German Cancer Aid (grant 110837 to Rita ...le Cancer; the Association “ Le cancer du sein, parlons-en! ” Award; ... See full document
9
Plasma osteoprotegerin and breast cancer risk in BRCA1 and BRCA2 mutation carriers
... annual risk for breast cancer in BRCA mutation carriers is ~2% between the ages of 30 and ...higher risk of developing disease who may be targets for alternative chemoprevention ... See full document
12
Molecular genetics analysis of hereditary breast and ovarian cancer patients in India
... and BRCA2 genes had been identified by linkage analysis and positional cloning on large breast cancer families in the early 1990's ...hereditary breast and ovarian cancer thus ... See full document
15
The androgen receptor CAG repeat polymorphism and modification of breast cancer risk in BRCA1 and BRCA2 mutation carriers
... reliable risk estimates, but point estimates (0.49 [P = 0.1] for BRCA1, ...for BRCA2) provided no evidence for increased risk associated with these large ...use. Risk estimates were not ... See full document
9
Evidence for SMAD3 as a modifier of breast cancer risk in BRCA2mutation carriers
... The candidate gene (or candidate SNP) approach for identifying potential risk modifiers has been successfully used to identify a SNP in the 5 ’ untranslated region of ...a genetic ... See full document
5
Common breast cancer susceptibility alleles are associated with tumour subtypes in BRCA1 and BRCA2 mutation carriers: results from the Consortium of Investigators of Modifiers of BRCA1/2
... National Cancer Program 2006 “ Alleanza contro il Cancro ” , and “ Progetto Tumouri Femminili ” ) and Ministero dell ’ Universita ’ e Ricerca (RBLAO3-BETH) to ...of BRCA1 and BRCA2 mutation ... See full document
44
The risk of contralateral breast cancer in patients from BRCA1/2 negative high risk families as compared to patients from BRCA1 or BRCA2 positive families: a retrospective cohort study
... from BRCA1 or BRCA2 positive families were proven mutation ...our risk estimates for contralateral breast cancer in BRCA1 and BRCA2 car- riers ...high risk ... See full document
7
Parity and breast cancer risk among BRCA1 and BRCA2mutation carriers
... by Breast Cancer Information Core [15]. All cases of breast or abdominal cancers are confirmed by means of hos- pital or pathology records from the Regional Cancer Regis- tries (data available ... See full document
9
Cost effectiveness of bilateral prophylactic mastectomy with and without different breast reconstruction techniques versus screening in women with high risk of breast cancer in the Canadian province of Ontario
... lifetime breast cancer risk and an 11% [95% CI: 2%–19%] lifetime ovarian cancer risk ...between BRCA2 mutations and an increased risk of pancreatic, gastric, bone, ... See full document
178
BRCA1 founder mutations do not contribute to increased risk of gastric cancer in the Polish population
... leucocytes. BRCA1 and BRCA2 mutation analysis was performed at the International Hereditary Cancer Center, Department of Genetics and Pathology, Pomeranian Medical Univer- ...in BRCA1 ... See full document
21
Associations of common breast cancer susceptibility alleles with risk of breast cancer subtypes in BRCA1 and BRCA2 mutation carriers
... of Cancer Research and Royal Marsden NHS Foundation Trust: Ros Eeles, Susan Shanley, Nazneen Rahman, Richard Houlston, Elizabeth Bancroft, Elizabeth Page, Audrey Ardern-Jones, Kelly Kohut, Jennifer Wiggins, Elena ... See full document
59
Common variants at 12p11, 12q24, 9p21, 9q31 2 and in ZNF365 are associated with breast cancer risk for BRCA1 and/or BRCA2mutation carriers
... Epidemiological study of BRCA1 & BRCA2 mutation carriers (EMBRACE) Douglas F. Easton is the PI of the study. EMBRACE Collaborating Centres are: Coordinating Centre, Cambridge: Susan Peock, ... See full document
12
Can multiple SNP testing in BRCA2 and BRCA1 female carriers be used to improve risk prediction models in conjunction with clinical assessment?
... Alongside risk factors with a genetic component there are several hormonal risk factors that are thought to be associated with breast cancer both among the general population and those ... See full document
7
No Sib Pair Concordance for Breast or Ovarian Cancer in BRCA1 Mutation Carriers
... and/or cancer registries, because our families are large, thereby minimizing the effect of calculation on the selection clusters in the families, because we have complete pedigree structures for close to all ... See full document
36
Breastfeeding and the risk of breast cancer in BRCA1 and BRCA2 mutation carriers
... for BRCA1 and BRCA2 mutations because of a personal and/or family history of breast and/or ovarian ...with breast or ovarian cancer. When a BRCA1 or BRCA2 ... See full document
9
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