[PDF] Top 20 Modelo para búsqueda y recuperación semántica en bibliotecas digitales

... that this interval is relatively fixed, not age- dependent, and mainly driven by neurodegen- eration. However, given their younger age at onset, pediatric patients with MS reach both mild and severe disability at ... See full document

... the treatment of migraine in adults and children were issued in October 2002 (see Appendix) ...the treatment of migraine in adults and children, paracetamol was the drug of choice favoured by ...as ... See full document

... as first line treatment and only ...the first line prescription treatment suggested, the second cicle of treatment proposed, and the time range recommended for the ... See full document

... Also of note in the randomized trials, was the higher incidence of infection in alemtuzumab-treated patients (73% in alemtuzumab-treated patients compared to 54% in interferon beta-1a-treated patients) (Table 4). This ... See full document

... Well- designed and executed randomized controlled trials provide the most reliable evidence on the efficacy of proposed health interventions. The conduct of an RCT is time-consuming, expensive and deals with moral and ... See full document

... OS was not reached in the nivolumab group, but it was 10.8 months in those patients who received dacarbazine. The OS rate at 1 year in the nivolumab- and dacarbazine-treated groups were 73% and 42%, respectively (Table ... See full document

... with pediatric patients demonstrate that PEG-ASNase is safe and tolerable, with lower or similar frequency than other ASNase formulations of toxic reaction to EC L-ASNase for front-line treatment of ... See full document

... for first-line therapy within the European Union, many questions remain about how the drug should best be ...that treatment may need to be given for ...new first-line study ... See full document

... 2.6 first-line treatment failures per 100 person- years and ranged between 2 to 5 per 100 ...on first- line treatment can severely limit the expected number of treatment ... See full document

... definite treatment option in relapsed/refractory CLL with high-risk features and inferior ...in first-line treatment needs to be fur- ther elucidated, particularly in comparison to the new ... See full document

... of treatment failure, defined as treatment switching or relapse treatment or death, with the assessment showing that IFN-b-1a-IM was inferior to the other IFN-bs and to glatiramer acetate in both ... See full document

... Given that the costs used in the analysis remain as expressed in the report, the critical difference in clinical benefit between the two treatments arms is five months. Below this difference the cost per extra LYG ... See full document

... early treatment approach using these monoclonal antibodies in combination for CLL patients with high-risk features was explored in a single-center Phase II ... See full document

... two first line antibiotics [10 (91%) and 9 (82%) ...third line antibiotics like Clindamycin, Vancomycin and Ciprofloxacin while Gram-negative isolates had a higher susceptibility to Ciprofloxacin and ... See full document

... If the first character of a line is 012, 014, or 021, the handler automatically enters Multiple Line Mode by setting bit 0 of the first word in the user's buffer to 1 and prints two line[r] ... See full document

... of first line managers is improved, but that the way in which they handle HRM issues has not altered to the same ...Many first line managers who were traditionally supervisors with no ... See full document

... with multiple mechanisms of action, including the state-depen- dent inhibition of sodium channels, the potentia- tion of -aminobutyric acid (GABA)-induced chlo γ - ride influx, the blockade of glutamate related ... See full document

... as first-line therapy in children and adults with convulsive status ...the first-line therapy for ...the management of a case of status epileptics during their ...the management ... See full document

... and management of adult ADHD, most of the data are based on experience derived from management of childhood ...and management of adult ADHD with special emphasis on the role of methylphenidate ... See full document

... of treatment regimen), early discontinuation (or short persistence) is the largest single factor for a decrease in adherence ...the first time are apt to feel fear and recur to treatment, while those ... See full document