[PDF] Top 20 Modelo de negócio e avaliação de empresas : o caso ISA
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Assessment of patients with idiopathic inflammatory myopathies and isolated creatin-kinase elevation
... activity assessment tool (MDAAT) is a combined tool that assesses muscle disease activity and extramuscular organ ...activity assessment (MYOACT) and the Myositis Intention to Treat Activities Index ... See full document
17
Favorable rituximab response in patients with refractory idiopathic inflammatory myopathies
... autoantibodies’ assessment, a commercially available line blot test kit (Myositis Profile Euroline Blot test kit, Euroim- mun, Lübeck, Germany) was used according to the manu- facturer’s protocol and to the ... See full document
7
The metastasis promoting protein S100A4 levels associate with disease activity rather than cancer development in patients with idiopathic inflammatory myopathies
... The data were described as median (IQR) if variables were not normally distributed and as mean (SD) if normally distributed. The Kruskal-Wallis test and cor- responding post-hoc analysis and Mann-Whitney test were ... See full document
12
Inflammatory lung disease a potential risk factor for onset of idiopathic inflammatory myopathies: results from a pilot study
... excluding patients with IBM and sarcoidosis expos- ure was ...For assessment of age and gender standardised mortality ratio (SMR), information on mortality among the general population aged 15 – 89 years by ... See full document
75
Resistin in idiopathic inflammatory myopathies
... The assessment of resistin staining intensity in inflam- matory infiltrates of the sections from muscle biopsies revealed a mean intensity of ...DM patients on the 0 to 3 ...MG patients were used as ... See full document
6
Cardiac involvement in adult and juvenile idiopathic inflammatory myopathies
... in patients with IIM is ...Myositis Assessment and Clinical Studies Group (IMACS) on the use of lipid-lowering therapy in patients with IIM showed that 76% of the IIM specialists prescribed ... See full document
16
Pulmonary arterial hypertension, a novelty in idiopathic inflammatory myopathies: insights and first experiences with vasoactive therapy
... among idiopathic inflammatory myopathy ...with assessment of PH by right heart catheterisation, extent of interstitial lung disease (ILD) and outcome of vasoactive ...of patients with IIM with ... See full document
15
Systematic protein protein interaction and pathway analyses in the idiopathic inflammatory myopathies
... There are currently no disease-specific treatments for IIM; instead anti-inflammatory, immunosuppressive and immunodulatory treatments are borrowed from other rheumatic diseases. Furthermore, despite treatment ... See full document
5
Role of non immune mechanisms of muscle damage in idiopathic inflammatory myopathies
... cally, patients show muscle infl ammation, fi ber degenera- tion, and overexpression of the MHC class I molecule ...many patients display isolated patches of infl ammation and degeneration in otherwise ... See full document
5
Microstructure and mineral composition of dystrophic calcification associated with the idiopathic inflammatory myopathies
... FTIR-RM, SEM/SDD-EDS and μCT maps and images The distribution of the calcified deposits within the tissue specimens differed among samples from different patients. In three specimens (Calc1, Calc2, and Calc10), ... See full document
17
Identification of multiple cancer associated myositis specific autoantibodies in idiopathic inflammatory myopathies: a large longitudinal cohort study
... population, patients with IIMs and anti-transcriptional intermediary factor (TIF1)- γ antibodies (SIR = ...the patients carrying anti-TIF1- γ , as well as other ...the patients with cancer-associated ... See full document
5
Bench to bedside review of myositis autoantibodies
... Idiopathic inflammatory myopathies represent a heterogeneous group of autoimmune diseases with systemic involvement. Even though numerous specific autoantibodies have been recognized, they have not ... See full document
94
MRI of skeletal muscles in patients with idiopathic inflammatory myopathies: characteristic findings and diagnostic performance in dermatomyositis
... of the nearby vessels. If the ‘foggy’ pattern was seen contig- uous with the ‘honeycomb’ pattern or ‘SHSI’ pattern, we described it as ‘honeycomb’ pattern or ‘SHSI’ pattern, respectively. Examples of actual MR images of ... See full document
324
Original Article Expression of adenosine receptors in muscle tissues from patients with idiopathic inflammatory myopathies
... Several studies have shown that A 3 AR plays an important role in regulating the inflammatory response and reducing tissue damage [11, 12]. In addition, applying A 3 AR agonists reduced serum creatine ... See full document
53
Clinical characteristics and favorable long-term outcomes for patients with idiopathic inflammatory myopathies: a retrospective single center study in China
... of patients in this study could be attributed to the follow- ing: (i) positive screening of ILD, cardiac involvement, PAH, and serologic tests at any time during the clinical ...our patients received ... See full document
13
Muscle shear wave elastography in idiopathic inflammatory myopathies: a case–control study with MRI correlation
... differently under the passive load acted upon by the limb weight. Participants were instructed to relax their muscles in all positions and were rested supine for 5 min before scanning. Two-dimensional SWE acquisitions ... See full document
5
Laboratory evaluation of the inflammatory myopathies.
... of patients with IIM, depending on the group of patients studied, and can be helpful in distinguishing the inflammatory myopa- thies from some other forms of muscle disease (86, 109, 116, ...some ... See full document
12
Elevated risk of venous thromboembolic events in patients with inflammatory myopathies
... Apart from ailments caused by the IMM itself, patients also suffer from venous thromboembolism (VTE) complica- tions that greatly affect the patient’s quality of life and prog- nosis. The objective of this review ... See full document
48
Muscle biopsy features of idiopathic inflammatory myopathies and differential diagnosis
... the inflammatory cells are similar to those seen in PM, consisting predominantly of macrophages and CD8? T cells which invade nonnecrotic muscle fibers that express MHC class I antigen on the sarcolemma [1, 5, 9, ... See full document
96
Immune mechanisms in the pathogenesis of idiopathic inflammatory myopathies
... of patients with polymyositis or dermatomyositis, supporting a role for B lymphocytes in these disease entities, but less often in patients with inclusion-body ...in patients with myositis, such as ... See full document
13
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