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Coating biomimetic nanoparticles with chimeric antigen receptor T cell-membrane provides high specificity for hepatocellular carcinoma photothermal therapy treatment
... of membrane proteins after the cell membrane coating on IMs, CD3 was quantified by flow cytometry on CIMs surface and comparing with that on CAR-T cells membranes with an equal amount of ... See full document
228
<p>Doxorubicin Delivered Using Nanoparticles Camouflaged with Mesenchymal Stem Cell Membranes to Treat Colon Cancer</p>
... of cell membranes, MSCs can be isolated from various tis- sues and increased in quantity in the ...develop biomimetic drug delivery platforms has become an area of intense research ... See full document
9
Preparation and Application of Cell Membrane-Camouflaged Nanoparticles for Cancer Therapy
... of nanoparticles can be easily engineered by coating particles with membrane derived from cells or bio-vesicles of different types ...resulting membrane-coated nanomedicines (CNs) are highly ... See full document
18
<p>Ferroptosis in Carcinoma: Regulatory Mechanisms and New Method for Cancer Therapy</p>
... Many genes, such as NFS1, Δ Np63 α and LSH, are involved in the regulation of ferroptosis. NFS1 activity is fundamental for maintaining iron-sulfur cluster biogenesis in high-oxygen environments such as the lung. NFS1 ... See full document
7
Nanostructured lipid carriers loaded with resveratrol modulate human dendritic cells
... internalization, cell labeling, and drug ...internalizing nanoparticles upon 1 hour of ...these nanoparticles, very small concentrations of rsv were sufficient to significantly decrease surface ... See full document
9
<p>Albumin exfoliated titanium disulfide nanosheet: a multifunctional nanoplatform for synergistic photothermal/radiation colon cancer therapy</p>
... The nanoparticles also produced a remarkable, synergistic, cytotoxic effect under PTT/RT irradiation, and showed great biocompatibility in vitro and in ...a new tumor therapeutic ... See full document
28
<p>New Aspects of Ultrasound-Mediated Targeted Delivery and Therapy for Cancer</p>
... immunotherapy. 122–125 DCs are well known as antigen- presenting cells that activate antigen-speci fi c T cell responses. DCs can be modi fi ed to present tumor-derived antigens to T cells. Thus harnessing the ... See full document
133
<p>Paclitaxel-Loaded Macrophage Membrane Camouflaged Albumin Nanoparticles for Targeted Cancer Therapy</p>
... albumin nanoparticles coated with macrophage plasma membranes as a means to achieve tar- geted therapy against malignant ...albumin nanoparticles have received great attention in both academia and ... See full document
19
<p>Hollow Prussian Blue Nanospheres for Photothermal/Chemo-Synergistic Therapy</p>
... 43.5% cell mortality rate; how- ever, the HPB nanospheres-DOX+NIR group leads to ...peutic therapy with the combination of chemo and thermal therapy can be calculated according to the previous ...and ... See full document
14
<p>The Pimpled Gold Nanosphere: A Superior Candidate for Plasmonic Photothermal Therapy</p>
... A new means of alternative cancer therapeutic complemen- tary techniques called “ plasmonic photothermal therapy ” is emphasized here to synthesize effective nanostructures with signi fi cant ... See full document
21
Safe and Immunocompatible Nanocarriers Cloaked in RBC Membranes for Drug Delivery to Treat Solid Tumors
... One cell type that has been widely explored as a source for membrane coating is the red blood cell (RBC), which represents nature’s own long circulating ...of nanoparticles with RBC ... See full document
22
<p>Molecular Antenna-Sensitized Upconversion Nanoparticle for Temperature Monitored Precision Photothermal Therapy</p>
... Tumor-bearing mice were subjected to thermal treatment 6 hrs after NPs were injected intravenously. Temperature and upconversion luminescence were imaged with a thermal machine and a CCD camera, respectively, as the ... See full document
15
pH-responsive perylenediimide nanoparticles for cancer trimodality imaging and photothermal therapy
... According to its structure, compound PPDI is amphiphilic with PDI core and hydrophilic PEG segment, which can self-assemble into nanoparticles (PPDI-NPs) in water. Transmission electron microscopy (TEM) images ... See full document
8
Recent Advances in Nanoparticle Shape and Composition Regulation Based on Galvanic Replacement for Cancer Treatment
... efficient photothermal conversion under laser irradiation, which is observed to be excellent for all these hollow ...including cancer treatment because of their high biocompatibility and excellent LSPR ... See full document
5
Novel Cs-Based Upconversion Nanoparticles as Dual-Modal CT and UCL Imaging Agents for Chemo-Photothermal Synergistic Therapy
... nanoparticles. However, the slight difference may not influence the application of UCNP for optical imaging. UCL targeted imaging of UCNP-ICG-RGDs in vitro was investigated using a laser scanning upconversion ... See full document
45
<p>SPOCK1 Involvement in Epithelial-to-Mesenchymal Transition: A New Target in Cancer Therapy?</p>
... between cancer cells and different extracellular ...of cell adhesion and elonga- tion but also latent ECM ...c cell ligands in the microenvironment of tumors depend on ECM compo- nents that are ... See full document
12
<p>Perioperative Targeted Therapy Or Immunotherapy In Non-Small-Cell Lung Cancer</p>
... The CheckMate-159 study (Table 2), 32 published in the New England Journal of Medicine in 2018, fi rst explored the ef fi cacy and safety of neoadjuvant immunotherapy for NSCLC. Twenty-one patients with untreated ... See full document
7
<p>Silver Nanoparticles for the Therapy of Tuberculosis</p>
... It is postulated that combining AgNPs and an antibiotic can synergistically inhibit both Gram + and Gram - multi- drug-resistant bacteria. 198 – 200 But this synergism is observed only for certain types of antibiotics, ... See full document
8
<p>Advances Of Chimeric Antigen Receptor T Cell Therapy In Ovarian Cancer</p>
... ovarian cancer, but no remission manifestations, such as tumor load reduction, were observed in this ...T cell receptor CD3 ζ chain signaling module alone (MOv19- ζ ) or in combination with the CD137 ... See full document
7
<p>Self-Assembly Nanoparticles for Overcoming Multidrug Resistance and Imaging-Guided Chemo-Photothermal Synergistic Cancer Therapy</p>
... ICG NPs (Figure 2D). DLS showed its average diameter is about 19.03 nm, which was smaller than ICG-Dox, the results of DLS also con fi rmed their size distributions displayed a cramped feature, which means T/Dox-ICG NPs ... See full document
8
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