[PDF] Top 20 Relación de Causalidad en Medicina Legal
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Human cellular restriction factors that target HIV-1 replication
... CA: caspid protein; CML: calcium modulating cyclophi- lin; CypA: cyclophilin A; Env: envelope protein; FIV: feline immunodeficiency virus; Gag: group specific antigen; GPI: glycosyl-phosphatidylinositol; HMM: high ... See full document
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Potent restriction of HIV 1 and SIVmac239 Replication by African Green Monkey TRIM5α
... TRIM5α restriction follows logarithmic kinetics with a strong, nearly absolute, block at lower MOIs that initially has small marginal reduc- tions in restriction with increasing virus ...cause ... See full document
5
Human cellular microRNA hsa miR 29a interferes with viral nef protein expression and HIV 1 replication
... the HIV-1 genome for all human ...four HIV-1 ...of HIV-1 (Fig. 1A). The predicted target site of hsa-miR-29a and 29b, located 407 bases into the nef transcript, is ... See full document
8
Determinants of Efficient Degradation of APOBEC3 Restriction Factors by HIV-1 Vif
... intra- cellular restriction factors against replication of HIV-1 (re- ferred to as HIV) ...ding HIV virions can restrict HIV replication in the next ... See full document
15
Cellular fatty acid synthase is required for late stages of HIV 1 replication
... by HIV-1 infection. HeLa-derived TZM-bl cells were infected with HIV-1, lysed 48 h post infection, and incu- bated with the purinome-capture ...ATP. HIV-infection increased the recovery ... See full document
5
Functional Analysis of the Human Immunodeficiency Virus Type 1 Rev Protein Oligomerization Interface
... of HIV-1 encodes a key activity for the complex regulation of viral gene ...the HIV-1 replication cycle to bring about the export from the nucleus to the cytoplasm of incompletely ... See full document
Cytokines Elevated in HIV Elite Controllers Reduce HIV Replication In Vitro and Modulate HIV Restriction Factor Expression
... with HIV. CD8-depleted PBMCs from individual donors were infected with HIV NL4-3 in the presence of the cytokines of interest, and then expression levels of CCR5/7, CXCR4, and CD69 were measured ...for ... See full document
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Human Immunodeficiency Virus Type 1 Employs the Cellular Dynein Light Chain 1 Protein for Reverse Transcription through Interaction with Its Integrase Protein
... chain 1 (DYNLL1, LC8, DLC1), dynein light chain Tctex-type 1 (DYNLT1), and p150 Glued have been implicated in cargo recruitment to the dynein complex during retrograde transport ...efficient ... See full document
14
Generation of Rhesus Macaque-Tropic HIV-1 Clones That Are Resistant to Major Anti-HIV-1 Restriction Factors
... these target residues with those of SIVmac239 (Table 1, MN4/SD and initial ...(Table 1 and ...by HIV- 1mt adaptation in macaque cells (19). Since viral replication effi- ciency was ... See full document
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An AP-1 Binding Site in the Enhancer/Core Element of the HIV-1 Promoter Controls the Ability of HIV-1 To Establish Latent Infection
... factor restriction were to be the driving force behind the establishment of latent HIV-1 infection, we hypothe- sized that it should be possible to generate virus LTR mutants that would establish ... See full document
342
Effects of Alpha Interferon Treatment on Intrinsic Anti-HIV-1 Immunity In Vivo
... several restriction factors con- tributes to IFN- ␣ suppression of HIV-1 in ...and replication (20). The lack of a relationship between restriction factor induction in PBMCs and ... See full document
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Role of Cellular RNA Processing Factors in Human Immunodeficiency Virus Type 1 mRNA Metabolism, Replication, and Infectivity
... viral replication and infectivity, several hnRNPs and SR proteins may be considered potential cellular targets for ...facto restriction factors whose expression decreases viral ... See full document
111
A Functional Role for ADAM10 in Human Immunodeficiency Virus Type 1 Replication
... known cellular roles for this complex pro- ...growth factors, receptors, and adhesion proteins, a process known as ectodomain ...in cellular adhesion, including ephrin-A2 (EFNA2), AXL, fractalkine ... See full document
6
Expression profile of host restriction factors in HIV 1 elite controllers
... against HIV-1, cell-intrinsic mechanisms may play an important role in mediating resistance to HIV-1 infection in elite ...with HIV-1 elite control and viral set point in viremic ... See full document
6
Restriction of HIV-1 replication by unique TRIM22 isoforms.
... with human immunodeficiency virus ...to HIV infection and why normal antiviral defenses are insufficient to fight infection is a key step towards creating better ...restricting HIV-1 ... See full document
6
Cell to Cell Spreading of HIV 1 in Myeloid Target Cells Escapes SAMHD1 Restriction
... While HIV-1 infection with cell-free viruses has been largely documented, cell-to-cell transmission probably represents the dominant mode of infection (23, ...by HIV-1, including cells of the ... See full document
72
Stem loop binding protein is a multifaceted cellular regulator of HIV 1 replication
... of HIV-1–infected individuals is able to maintain plasma viral load (VL) at low levels without antiretroviral ...20 HIV-1–infected individuals who maintained either high or low VL with the aim ... See full document
7
SAMHD1: a new insight into HIV 1 restriction in myeloid cells
... differentiated human monocytic THP-1 cells that express tagged Vpx ...to HIV-1 infection by transduction of SIVsm/HIV-2 Vpx-contain- ing virus-like particles derived from SIVmac ... See full document
6
Two Families of Env Antibodies Efficiently Engage Fc-Gamma Receptors and Eliminate HIV-1-Infected Cells
... cells presenting Env in its open CD4-bound conformation (17–21, 26, 30, 58–60). Among the different nnAbs tested for their ADCC activity, the members of the anti- cluster A family of Abs were identified as being the most ... See full document
53
Evidence that Lo's mycoplasma (Mycoplasma fermentans incognitus) is not a unique strain among Mycoplasma fermentans strains
... Furthermore, the replication of human immunodeficiency virus type 1 HIV-1, determined by reverse transcriptase activity and HIV-1 p24 antigen level, in peripheral blood mononuclear cells[r] ... See full document
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