[PDF] Top 20 Salud pública y sistema sanitario. Informe SESPAS 2010
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Assessment of Cytotoxicity of Dimethyl Sulfoxide in Human Hematopoietic Tumor Cell Lines
... incubation time, the medium was replaced with 100 μl of fresh medium. The amount of 10 μl of MTT solution (5 mg/ ml in PBS) was then added to each well and incubated at 37°C for 4 hours. Then, 100 μl of the SDS-HCl ... See full document
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Cytotoxicity Assessment of Organotin(IV) (2-Metoxyethyl) Methyldithiocarbamate Compounds in Human Leukemia Cell Lines
... The methods of treatment for cancer vary and depend on the types of cancer involved. According to Wust et al., (2002), the main cancer treatment methods are surgery, radiotherapy and chemotherapy. Surgery works best for ... See full document
7
The Cytotoxicity Evaluation f Seven Species of Artemisia on Human Tumor Cell Lines
... mentioned human tumor cell lines was determined by a rapid colorimetric assay, using MTT [3-(4,5- dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide, Sigma, Germany] and compared with ... See full document
21
Original Article Diallyl trisulfide inhibits proliferation and promotes apoptosis of side population cells in multiple myeloma cells
... of tumor stem ...study, human MM RPMI-8226 and NCI-H929 cell lines were treated with different concentrations of DATS (2, 5, 10, 20, 40, or 80 μM) for 1, 2, or 3 days and the half-maximal ... See full document
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Cytotoxicity of Ethyl Acetate Extract of Endophytic Aspergillus fumigatus on A549 Cell Lines
... the cytotoxicity of endophytic Aspergillus fumigatus of Justicia ...cancerous cell line and a specific increased cytotoxicity to cancer cell line make the compound an interesting lead molecule ... See full document
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Tumor necrosis factor expression in human epithelial tumor cell lines
... vitro cytotoxicity for some but not all tumor ...epithelial tumor cell lines. Eleven of these cell lines were resistant to the growth inhibitory effects of TNF (50% ... See full document
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Molecular Cytotoxic Mechanisms of 1-(3,4,5-Trihydroxyphenyl)-dodecylbenzoate in Human Leukemia Cell Lines
... cell lines. Since new compounds with biological activity and less cytotoxicity to normal cells are necessary for cancer therapy, the aim of this study was to evaluate the cytotoxic effect of ... See full document
6
Ex-vivo expanded human NK cells express activating receptors that mediate cytotoxicity of allogeneic and autologous cancer cell lines by direct recognition and antibody directed cellular cytotoxicity
... of cell separator (Elutra, Gambro ...and cell density, five elu- triated cell fractions were ...elutriated cell fractions were viably frozen in RPMI-1640 (Invitrogen ...20% human AB ... See full document
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Virus production and hemoglobin synthesis in variant lines of dimethyl sulfoxide-treated Friend erythroleukemia cells.
... Treatment of the cultures with dimethyl sulfoxide DMSO stimulates erythroid differentiation accompanied by increased hemoglobin synthesis 12, as well as virus production 15, 27, 33.. Thu[r] ... See full document
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Enhanced infectivity of adenovirus type 2 DNA and a DNA-protein complex.
... It was recently reported that the infectivity of herpesvirus type 1 DNA could be increased by treatment of cell monolayers with dimethyl sulfoxide Me2SO after transfection with the calci[r] ... See full document
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Anti inflammatory evaluation of the methanolic extract of Taraxacum officinale in LPS stimulated human umbilical vein endothelial cells
... mononuclear cell adhesion, given that its cognate ligand, the integrin very late antigen-4, is selectively expressed on monocytes (and on some T lympho- cytes) but not on neutrophils ... See full document
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Synthesis, antitumor evaluation and molecular modeling study of novel benzimidazoles and pyrazinobenzimidazoles
... individual cell lines, compound 5a showed selective inhibition against HepG2 and MCF-7 cell ...B cell line with IC 50 reached 2.5 µg/ml. The results of the cytotoxicity of ... See full document
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Piperolein B, isopiperolein B and piperamide C9:1(8E): total synthesis and cytotoxicities
... cell type-dependent. Of the three compounds, 3, the reported structure of isopiperolein B, was the most cytotoxic and piperamide C9:1(8E), 2 was the least cytotoxic demonstrating that the length of the connecting ... See full document
18
Clinical grade generation of peptide stimulated CMV/EBV specific T cells from G CSF mobilized stem cell grafts
... The rationale of strengthening specific T-cell immu- nity for both prevention and therapy of CMV and EBV reactivation therefore represents an intriguing thera- peutic option. Several groups have shown that CMV- or ... See full document
6
In vitro cytotoxicity of Parthenium hysterophorus extracts against human cancerous cell lines
... of human cancer cell lines and to select a better extract is a matter of ...different cell specificity and cascade mechanisms followed by different ...in human leukemia HL-60 ... See full document
7
Metformin combined with aspirin significantly inhibit pancreatic cancer cell growth in vitro and in vivo by suppressing anti- apoptotic proteins Mcl-1 and Bcl-2
... The mTOR signaling pathway has been reported to regulate Mcl-1 at both transcriptional and translational levels [48, 50]. mTOR also can indirectly regulate proteasome degradation of Mcl-1 by repressing GSK3 [51]. . In ... See full document
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Oncolytic Virotherapy Synergism with Signaling Inhibitors: Rapamycin Increases Myxoma Virus Tropism for Human Tumor Cells
... in human tumor cells gar- nered interest in the viral and cellular host range factors that could be responsible for this unique cross-species ...in human tumor cells ...the cell cycle ... See full document
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Enhanced antitumor activity of doxorubicin in breast cancer through the use of poly(butylcyanoacrylate) nanoparticles
... against human and mouse breast carcinoma cells, given the important reduction of the IC 50 ...of tumor growth and that the use of PBCA NPs reduces DOX ... See full document
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Terpenes from soft corals of the genus Lobophytum (Alcyoniidae): Chemistry and biological activities
... The soft coral Lobophytum durum, resulted seventeen cembranolide named durumolides A-L(24-35)with a trans- fused -methylene- -lactone and durumolides M–Q(36-40)possessing an α-methoxymethyl-γ-lactone 3,12,13 . Compounds ... See full document
8
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... and cell surface markers (cluster of differentiation [CD31], CD44, CD45, and CD90) by flow cytometry was analyzed before and after the ...slow-freezing. Cell viability was assessed by trypan blue exclusion ... See full document
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