[PDF] Top 20 Sobre la experiencia religiosa: aproximación fenomenológica
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Collagen density promotes mammary tumor initiation and progression
... breast density are not only associated with increased epithelial and stromal cellular- ity [12-14], but also significantly increased fibrillar colla- gen deposition ...total collagen increase as ... See full document
59
Neutrophils drive accelerated tumor progression in the collagen dense mammary tumor microenvironment
... a tumor-associated neutrophil (TAN) population analo- gous to ...of tumor growth are more cytotoxic to tumor cells by either directly killing tumor cells or by secreting reactive oxygen ... See full document
12
Adipocyte derived collagen VI affects early mammary tumor progression in vivo, demonstrating a critical interaction in the tumor/stroma microenvironment
... 1 promotes cellular proliferation via p27 Kip1 degradation, and metallothionein-1f/1e is corre- lated with poor patient prognosis in breast ...data, collagen VI mediated the upregulation of metallothio- ... See full document
24
Estrogen promotes estrogen receptor negative BRCA1 deficient tumor initiation and progression
... in tumor development and progression [12, ...in tumor initiation and ...proficient tumor cells in vitro and tumorigenesis in ...-deficient mammary tumor cells, promoting ... See full document
21
COX 2 modulates mammary tumor progression in response to collagen density
... increased collagen deposition that occurs around tumors, even in the PyMT/Col1a1 ...with tumor growth and pro- gression to metastasis in the involuting mammary gland ...greater collagen ... See full document
8
ADAM17 in tumor associated leukocytes regulates inflammatory mediators and promotes mammary tumor formation
... the tumor microenvironment has been tightly linked to mammary tumor formation and ...between tumor cells and infiltrating macrophages can contribute to the generation of a pro-tumorigenic ... See full document
19
Collagen density regulates the activity of tumor-infiltrating T cells
... different collagen densities impairs proliferation without compromising viability To investigate if 3D culture in collagen matrices of different collagen concentrations affected the viability of T ... See full document
23
<p>Overexpression of COL5A1 promotes tumor progression and metastasis and correlates with poor survival of patients with clear cell renal cell carcinoma</p>
... The COL5A1 mRNA expression in patients with metastatic ccRCC was significantly higher compared to patients with localized ccRCC (P < 0.001; Figure 2A). Based on the median level of COL5A1 mRNA (1.70-fold) in ccRCC ... See full document
79
Upregulation of valosin-containing protein (VCP) is associated with poor prognosis and promotes tumor progression of orbital B-cell lymphoma
... of Chinese People’s Armed Police Forces (Beijing, China) from December 2008 to December 2012, with follow-up until January 2018. We received a documented review and approval from the ethics committee for all studies ... See full document
9
A mouse mammary tumor virus promoter element near the transcription initiation site.
... A similar sequence was observed near the major transcription initiation site for the SV40 late promoter, and a protein in crude nuclear extracts was shown to footprint on SV40 sequences [r] ... See full document
1
Adipocyte derived endotrophin promotes malignant tumor progression
... in tumor tissues. To further investigate a role of COL6 in tumor progression, particularly in the context of ETP, we generated polyclonal antibodies specific for either mouse or human ETP domains ... See full document
102
Compression-induced dedifferentiation of adipocytes promotes tumor progression
... Polyacrylamide gels of various stiffnesses were fabricated on 35-mm glass-bottom culture dishes (MatTek, Ashland, MA). Briefly, the bottom no. 1 coverslip was aminosilanized to enable polyacrylamide attach- ment. Gel ... See full document
27
Antibody-based targeting of alternatively spliced tissue factor: a new approach to impede the primary growth and spread of pancreatic ductal adenocarcinoma
... of tumor size by RabMab1 led to a 3-fold reduction of the circulating levels of asTF from 600 pg/mL to ~200 pg/ml (Figure 3): last year, we reported that pre-operative circulating levels of asTF ≥ 200 pg/ml may ... See full document
126
Evaluation of tumor hypoxia and proliferation in canine spontaneous solid tumors
... the tumor had no or a minimum fraction of hypoxic tumor ...of tumor oxygenation that bears a relationship to prognosis. Tumor hypoxia is an important independent poor prognostic factor in ... See full document
50
Emerging clinical significance of claudin-7 in colorectal cancer: a review
... enhanced tumor growth and invasiveness in nude mice through a mouse model of ...a tumor suppressor involved in CRC ...of tumor formation, whereas knockdown of claudin-7 in the HT-29 or DLD-1 cell ... See full document
49
Leptin promotes melanoma tumor growth in mice related to increasing circulating endothelial progenitor cells numbers and plasma NO production
... studies indicated that the EPC derived from bone marrow also contributes to tumor vasculogenesis [3-5,39]. How- ever the extent of EPCs incorporation into the tumor vas- culature has been a subject of ... See full document
6
High mammographic density is associated with an increase in stromal collagen and immune cells within the mammary epithelium
... mouse mammary glands led to hyperpla- sia and tumour growth, suggesting aromatase’s tumori- genic potential when its expression becomes aberrant ...culture density and in- creased ECM presence significantly ... See full document
5
PIM1 regulates glycolysis and promotes tumor progression in hepatocellular carcinoma
... Hepatocellular carcinoma (HCC) is one of the most malignant cancers worldwide and highly prevalent in China and Southeast Asia. Characteristically, HCC is rapidly proliferating and often outpaces its functional blood ... See full document
69
RhoE is required for contact inhibition and negatively regulates tumor initiation and progression
... MEFs of each genotype were plated on 35 mm dishes. Every three days cells were trypsinized, counted and replated at the same density. The number of divisions (population doubling level, PDL) was calculated using ... See full document
205
Elevated expression of Tiam1 is associated with poor prognosis and promotes tumor progression in pancreatic cancer
... and progression of PC, loss-of-function experi- ments were first performed to knockdown the expression of Tiam1 in SW1990 cells and BxPC-3 using a specific plasmid ... See full document
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