[PDF] Top 20 Viabilidad de semillas de guabijuzeiro en almacenamiento
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Clinical significance of epithelial-mesenchymal transition
... cytoskeleton as a prerequisite for lamellipodia and filopodia formation, such as Rho, Rac and Cdc42 [31]. Vimentin, which is frequently upregulated in cells with an EMT-like phenotype, is then required for the further ... See full document
55
Expression of the epithelial-mesenchymal transition-related proteins and their clinical significance in lung adenocarcinoma
... Characteristics of EMT include complete loss of epi- thelial polarity, loss of epithelial markers and acquisition of mesenchymal markers. In addition to processes in- volving complete EMT, many processes ... See full document
5
Original Article Expression of TWIST, an inducer of epithelial-mesenchymal transition, in nasopharyngeal carcinoma and its clinical significance
... from epithelial morphology and physiology to the mesenchymal phenotype ...and clinical stage, inconsistent with evidence that tumor volumes were associat- ed with an inreased incidence of nodal ... See full document
31
Role of microRNA in epithelial to mesenchymal transition and metastasis and clinical perspectives
... Because epithelial plasticity must be finely regulated along the metastatic cascade, miRNAs have emerged as critical regu- lators necessary for metastatic ...regulate epithelial plasticity, such as ... See full document
27
Clinicopathological significance of KAI1 expression and epithelial mesenchymal transition in non small cell lung cancer
... EMT has been found to be critical in tumor dissemin- ation, local invasion, and metastasis, endowing cells with cancer stem cell properties [29–31]. Its common charac- teristic is downregulation of E-cad expression and ... See full document
168
Clinicopathological and prognostic significance of epithelial mesenchymal transition-related protein expression in intrahepatic cholangiocarcinoma
... statistical significance of the relationship between clinicopathological variables and expression of individual EMT-related ...Statistical significance was set at P , ... See full document
12
Role and prognostic significance of the epithelial-mesenchymal transition factor ZEB2 in ovarian cancer
... In a panel of ovarian adenocarcinoma cell lines we found that the different epithelial and mesenchymal markers display a wide degree of expression variability. These findings likely reflect the progressive ... See full document
59
Morphological and immunohistochemical identification of epithelial-to-mesenchymal transition in clinical prostate cancer
... Although N-cadherin overexpression occurred preferentially in Gleason grade 4 ill-defined growth pattern, a significant number of ill-defined structures did not express N-cadherin. It is possible that other cadherins ... See full document
79
Epithelial to mesenchymal transition and breast cancer
... of epithelial and stromal cell ...and clinical features that allow evaluation of different aspects representing some of the heterogeneity seen in breast ...the epithelial origin, it was clearly shown ... See full document
6
Significance of the NOR1-FOXA1/HDAC2-Slug regulatory network in epithelial-mesenchymal transition of tumor cells
... The epithelial-mesenchymal transition (EMT) process is believed to play a crucial role in nasopharyngeal carcinoma (NPC) progression, a squamous cell carcinoma of the head and neck with the tendency ... See full document
81
The role of epithelial–mesenchymal transition programming in invasion and metastasis: a clinical perspective
... Abstract: Epithelial–mesenchymal transition (EMT) is involved in normal developmental cellular processes, but it may also be co-opted by a subset of cancer cells, to enable them to invade and form ... See full document
43
Novel clinical therapeutics targeting the epithelial to mesenchymal transition
... pathway, mesenchymal to epithe- lial transition ...of epithelial nephrons which require the transcription fac- tor Pax-2 to initiate ...to transition cells to an epithelial phenotype, ... See full document
17
The translational significance of epithelial-mesenchymal transition in head and neck cancer
... EMT remains a controversial pathobiological model in the clinical setting, and some question the validity of the concept outside of the confines of in vitro conditions and embryonal development [37]. Despite these ... See full document
92
Corepressor metastasis-associated protein 3 modulates epithelial-to-mesenchymal transition and metastasis
... and mesenchymal movement, and (2) collective migration, involving the movement of cells in the form of sheets, strands, clusters, or ducts rather than individually ... See full document
85
Original Article MiR-211 inhibits cell epithelial-mesenchymal transition by targeting MMP9 in gastric cancer
... To investigate the expression of miR-211 in GC, we detected 72 paired tumor tissues and adja- cent normal tissues in patients by performing qRT-PCR. As shown in Figure 1, the miR-211 expression levels were lower in GC ... See full document
148
Heparin binding epidermal growth factor (HB EGF) drives EMT in patients with COPD: Implications for disease pathogenesis and novel therapies
... increased epithelial expression of mesenchymal markers such as S100A4 and vimentin in large and small airways of COPD patients compared to non-smokers (30, ...whose epithelial and Rbm cell expression ... See full document
15
Expression of zinc finger transcription factors (ZNF143 and ZNF281) in serous borderline ovarian tumors and low-grade ovarian cancers
... underwent clinical stage-appropriate surgical resections of ovarian tumors, and whenever necessary, received adjuvant platinum-based chemotherapy as recommended by current Polish guidelines ... See full document
12
Epithelial mesenchymal transition and its implications for fibrosis
... GTPase modulation of cell shape and movement. Epithelia that undergo EMT during development, inflammation, or carcinogenesis become mesenchymal cells, fibroblasts, or metastatic tumor cells, respectively (19, 72, ... See full document
30
<p>Epithelial–mesenchymal transition is driven by transcriptional and post transcriptional modulations in COPD: implications for disease progression and new therapeutics</p>
... (Wnt)-mediated epithelial changes could also be crucial in COPD EMT ...bronchial epithelial cells showed that nicotine, which is a major component of tobacco smoke, could induce EMT in a WNT-3A/ β ... See full document
7
OVOL guides the epithelial-hybrid-mesenchymal transition
... of Epithelial-to-Mesenchymal Transition (EMT) and its ...hybrid epithelial/mesenchymal (E/M) phenotype that has maximum cellular plasticity and allows migration of Circulating Tumor ... See full document
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