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Heterotrimeric G-Protein Subunit Function in Candida albicans: both the α and β Subunits of the Pheromone Response G Protein Are Required for Mating
... contain heterotrimeric G-protein modules have been identi- ...␣ subunits and usually a single ␥ pair. An excess of ␣ subunits is also found in higher eukaryotes such as mammals, in ... See full document
141
Ste18p Is a Positive Control Element in the Mating Process of Candida albicans
... the G␥ subunit of the C. albicans mating response G protein generates ...the function is in any way mating type ...the G␥ subunit is similar to ... See full document
8
Gpa2, a G-Protein α Subunit Required for Hyphal Development in Candida albicans
... GTP-binding protein Ras and het- erotrimeric G proteins are involved in the transmission of external ...C. albicans a single Ras protein has been described (18, ...in both the Efg1 and ... See full document
11
A Phytophthora sojae G-Protein α Subunit Is Involved in Chemotaxis to Soybean Isoflavones
... involving heterotrimeric G proteins are probably the most ubiquitous and best studied among ...The G-protein complex, which is composed of ␣ ,  , and ␥ subunits, is activated by a ... See full document
98
A Phytophthora infestans G-Protein β Subunit Is Involved in Sporangium Formation
... The heterotrimeric G-protein pathway has been identified as an important regulator of development and physiology in plant-pathogenic fungi (3, 17, ...the function of G␣ subunits ... See full document
141
Multiple Roles of a Heterotrimeric G-Protein γ-Subunit in Governing Growth and Development of Aspergillus nidulans
... Gb- subunit (SfaD) functions as a heterodimer with the cog- nate G g -subunit in ...is required for normal vegetative growth and developmental ... See full document
24
Basidiomycete Mating Type Genes and Pheromone Signaling
... B mating type locus seems to be rep- resented by receptors homologous to ...A pheromone is encoded in close proximity to the Pleurotus djamor receptor, while no pheromone genes were linked to the ... See full document
9
The Heterotrimeric G-Protein Subunits GNG-1 and GNB-1 Form a Gβγ Dimer Required for Normal Female Fertility, Asexual Development, and Gα Protein Levels in Neurospora crassa
... The gng-1 replacement mutation and complementation by gng-1 ⴙ in trans. The gng-1 ORF is located only 790 bp away from the 3⬘ end of the insert in genomic clone #31. To make a gene replacement construct, a larger genomic ... See full document
161
Mot3, a Zn Finger Transcription Factor That Modulates Gene Expression and Attenuates Mating Pheromone Signaling in Saccharomyces cerevisiae
... of pheromone response and pheromone-induced gene expression and to require an intact signaling pathway to exert its ...of pheromone-responsive genes by mechanisms distinct from those used by ... See full document
45
A G-Protein β Subunit Required for Sexual and Vegetative Development and Maintenance of Normal Gα Protein Levels in Neurospora crassa
... Deletion of gnb-1 does not greatly impact apical extension rate but influences mass accumulation and conidiation on solid medium. N. crassa grows vegetatively by apical extension and fusion of septated hyphae to form the ... See full document
59
Polarity mediates asymmetric trafficking of the Gβ heterotrimeric G protein subunit GPB 1 in C elegans embryos
... also required for fission and fusion events within the endosomal pathway (reviewed by Praefcke and McMahon, ...dynamin function by overexpression of a temperature-sensitive mutant leads to defects in ... See full document
8
Polycystin 1 loss of function is directly linked to an imbalance in G protein signaling in the kidney
... kidney function, dilated pronephric tubules and ducts, and the loss of the expression of the sodium bicarbonate co-transporter Nbc1 in the late distal tubule (Tran et ...trimeric G-protein signaling ... See full document
16
Deletion of the α subunit of the heterotrimeric Go protein impairs cerebellar cortical development in mice
... After immunostaining PFs in Gnao −/− mice with an anti- vGluT1 antibody, we found a generalized reduction in the thickness of the ML, but no more specific abnormal- ities (Additional file 2). Immunostaining of Gnao −/− ... See full document
72
The pheromone receptors inhibit the pheromone response pathway in Saccharomyces cerevisiae by a process that is independent of their associated G alpha protein.
... Truncations that deleted a larger region of the cytoplasmic tail did not produce functional protein as determined by complementation of a ste3::LEU2 allele in MATa cells [r] ... See full document
94
Remasking of Candida albicans β Glucan in Response to Environmental pH Is Regulated by Quorum Sensing
... a protein or nucleotide, the supernatants were heat inactivated and treated with protei- nase K, DNase, or ...in response to pH, although other factors may also play a ... See full document
116
The Gα Subunit Signals through the Ste50 Protein during the Mating Pheromone Response in the Yeast Kluyveromyces lactis
... activates mating by an unknown mechanism requir- ing Scp160 (7), an RNA binding protein that is predominantly associated with the nuclear envelop and with the endoplasmic reticulum (39, ...is ... See full document
12
Subunit interactions of vesicular stomatitis virus envelope glycoprotein stabilized by binding to viral matrix protein.
... Fluorescein-labeled G proteins from VSV-IND and VSV-NJ were incubated at a G protein subunit concentration of 4 nM for 30 min to allow the subunits to dissociate and then mixed with nucl[r] ... See full document
5
MFα1, the Gene Encoding the α Mating Pheromone of Candida albicans
... Candida albicans, the single most frequently isolated human fungal pathogen, was thought to be asexual until the recent discovery of the mating-type-like locus ...in mating than white-phase ... See full document
72
The heterotrimeric G protein β subunit RGB1 is required for seedling formation in rice
... The G protein γ subunits AGG1, AGG2, and AGG3 provide functional selectivity in Gβγ dimer signaling, and the triple gamma mutant (agg1agg2agg3) exhibits the phenotype of the agb1 mutant (Thung et ... See full document
186
The Gβ-Subunit-Encoding Gene bpp1 Controls Cyclic-AMP Signaling in Ustilago maydis
... a pheromone-receptor ...to heterotrimeric G proteins. Of four G ␣ subunits in ...a function during mating and cyclic AMP (cAMP) ...induces pheromone gene ... See full document
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