[PDF] Top 20 Balance General o Estado de Situacion Financiera pdf
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Efficacy and tolerability of fixed-combination bimatoprost/timolol versus fixed-combination dorzolamide/brimonidine/timolol in patients with primary open-angle glaucoma or ocular hypertension: a multicenter, prospective, crossover study
... The study recruited patients >17 years of age with a diagnosis of mild to moderate POAG or OHT who had failed to reach target IOP despite receiving bim/tim or dorz/brim/tim for at least 1 ...month. ... See full document
9
A combined analysis of five observational studies evaluating the efficacy and tolerability of bimatoprost/timolol fixed combination in patients with primary open-angle glaucoma or ocular hypertension
... The primary efficacy outcome was mean change in IOP (measured using contact tonometry) in each eye from baseline to the end of the study (approximately 12 weeks, based on routine clinical ... See full document
10
Comparative Evaluation of the Efficacy of the Bimatoprost 0 03%, Brimonidine 0 2%, Brinzolamide 1%, Dorzolamide 2%, and Travoprost 0 004%/Timolol 0 5% Fixed Combinations in Patients Affected by Open Angle Glaucoma
... the efficacy and safety of BRIMOTFC versus the unfixed components or another fixed combination ...brinzolamide-0.5% timolol ophthalmic suspension is associated with a statistically ... See full document
33
A Comparative Evaluation of Efficacy and Tolerability of Fixed Drug Combination of Brimonidine and Timolol with Timolol Monotherapy in Patients with Primary Open-Angle Glaucoma: An Open Labeled Prospective Study
... This study was conducted to compare and evaluate the efficacy and tolerability of fixed-dose combination of Brimonidine-Timolol with Timolol monotherapy in ... See full document
178
Fixed combination of bimatoprost and timolol in patients with primary open-angle glaucoma or ocular hypertension with inadequate IOP adjustment
... an open-label observational study including many ...a study has inherent limitations, which must be ...the study means that there could be no washout period between the earlier prior ... See full document
7
Preference for a fixed combination of brinzolamide/timolol versus dorzolamide/ timolol among patients with open-angle glaucoma or ocular hypertension
... a multicenter, prospective, patient-masked, ran- domized, interventional, crossover 3-day ...0), patients were assessed for study ... See full document
18
Preservative-free bimatoprost 0.03%/timolol 0.5% fixed combination in patients with glaucoma in clinical practice
... This open-label, observational study looked at the efficacy and AE profile of, and compliance to, PF FC bimatoprost ...IOP-lowering efficacy and safety of PF FC bimatoprost ... See full document
16
Clinical utility and differential effects of prostaglandin analogs in the management of raised intraocular pressure and ocular hypertension
... topical ocular hypotensive agents available for the treatment of elevated intraocular pressure ...latanoprost, bimatoprost and travoprost compared with timolol ...0.5%, brimonidine 0.2%, or ... See full document
30
The impact of timolol maleate on the ocular tolerability of fixed-combination glaucoma therapies
... of patients with elevated IOP will require more than one medication to obtain a modest 20% reduction in IOP, and as a result, some patients may require two medications, provided in either two separate ... See full document
8
Update and optimal use of a brinzolamide-timolol fixed combination in open-angle glaucoma and ocular hypertension
... of glaucoma and therefore are important to consider when evaluating treatment ...options. Ocular perfusion is increasingly recognized as potentially playing a role in the ...randomized, crossover, ... See full document
12
Efficacy and safety of travoprost/timolol vs dorzolamide/timolol in patients with open-angle glaucoma or ocular hypertension
... the primary inference was based on the comparisons of mean IOP between the two treatment groups across the four on-therapy visits and time points using the intent-to-treat ...IOP-lowering efficacy ... See full document
30
Study of ocular hypotensive effect and tolerability of fixed-combination Brinzolamide 1% and brimonidine 0.2% in Indian eyes with open angle glaucoma
... solution. Brimonidine is contraindicated in children due to cardiovascular instability, lethargy and ...of brimonidine occurs with peak plasma concentration within 1-4 ...in fixed combination ... See full document
5
Efficacy and safety of benzalkonium chloride-free fixed-dose combination of latanoprost and timolol in patients with open-angle glaucoma or ocular hypertension
... dB. Patients were excluded if they had had intraocular conventional surgery or laser surgery within the past 6 months, refractive surgery in the study eye, or ocular trauma within the previous 3 ... See full document
5
Phase III safety and efficacy study of long-term brinzolamide/timolol fixed combination in Japanese patients with open-angle glaucoma or ocular hypertension
... current study was to evaluate the long- term safety and efficacy of BRINZ/TIM-FC in Japanese patients with open-angle glaucoma (primary open-angle, ... See full document
21
Twelve-week, randomized, multicenter study comparing a fixed combination of brimonidine-timolol with timolol as therapy adjunctive to latanoprost
... randomized patients received at least one dose of study medication and were included in the safety ...72 patients in each group would provide 80% power to detect a ...the primary outcome. The ... See full document
5
Managing refractory glaucoma with a fixed combination of bimatoprost (0.03%) and timolol (0.5%)
... States, glaucoma is the second leading cause of blindness in the gen- eral population, and the leading cause of blindness in black ...of glaucoma (Hayreh 1969; Ernest 1975; Sossi and Anderson 1983). ... See full document
32
Comparison of the latanoprost 0.005%/timolol 0.5% + brinzolamide 1% versus dorzolamide 1%/timolol 0.5% + latanoprost 0.005%: a 12-week, randomized open-label trial
... this study is that dorzolamide is used at 1% concentrations in Japan, however 2% solutions are used in European countries and the ...dose-response study that the percentage reduction from baseline ... See full document
18
Safety and efficacy of switching from dorzolamide 1.0%/timolol maleate 0.5% eye drops to brinzolamide 1.0%/timolol maleate 0.5% eye drops
... a fixed-combination eye drop that contains two different medications is ...Several fixed-combination eye drops have been approved for use in Japan and have been available since ...include ... See full document
6
Clinical effectiveness of brinzolamide 1%–brimonidine 0.2% fixed combination for primary open-angle glaucoma and ocular hypertension
... Some of the warnings to be kept in mind while using BBFC include sulfonamide hypersensitivity, the risk of corneal edema, and caution about the use of the product in patients with severe renal impairment, because ... See full document
10
Comparative efficacy and safety of the fixed versus unfixed combination of latanoprost and timolol in Chinese patients with open-angle glaucoma or ocular hypertension
... closed/barely open anterior cham- ber angle or a history of acute angle-closure glaucoma; (2) ocular surgery in one or both eyes within 3 months prior to the screening visit; (3) any ... See full document
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