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[PDF] Top 20 Determination of erlotinib in rabbit plasma by liquid chromatography mass spectrometry

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Determination of erlotinib in rabbit plasma by liquid chromatography mass spectrometry

Determination of erlotinib in rabbit plasma by liquid chromatography mass spectrometry

... Electrospray ionization (ESI) source was applied and operated in posi- tive ion mode; multiple reaction monitoring (MRM) mode was used to quantification using target frag- ment ions m/z[r] ... See full document

1

Development and validation of LC-ESI-MS method for the quantification of dapoxetine in rat plasma

Development and validation of LC-ESI-MS method for the quantification of dapoxetine in rat plasma

... A sensitive and simple liquid chromatography/electrospray mass spectrometry (LC-ESI-MS) method for determination of dapoxetine in rat plasma using one-step protein precipitation was deve[r] ... See full document

1

Simultaneous determination of prodrug of Ginkgolide B and Ginkgolide B in rat plasma by LC-MS/MS

Simultaneous determination of prodrug of Ginkgolide B and Ginkgolide B in rat plasma by LC-MS/MS

... A simple and sensitive liquid chromatography tandem mass spectrometry (LC-MS/MS) method was established and validated for the determination of prodrug of ginkgolide B (PGB) and its metab[r] ... See full document

1

Determination of sub ppb epichlorohydrin levels in water by on line solid phase extraction liquid chromatography/tandem mass spectrometry

Determination of sub ppb epichlorohydrin levels in water by on line solid phase extraction liquid chromatography/tandem mass spectrometry

... transitions of a HPLC-grade water blank, a reference standard and the DWTP1 sample spiked both.. It can be seen the robustness of the analyte and IS retention times as well as the good.[r] ... See full document

28

Pharmacokinetics of andrographolide dripping pills, a modern chinese herb medicine, by LC-MS/MS method in beagle dogs

Pharmacokinetics of andrographolide dripping pills, a modern chinese herb medicine, by LC-MS/MS method in beagle dogs

... A rapid and sensitive method for the analysis of andrographolide in dog plasma using liquid chromatography coupled to tandem electrospray ionization mass spectrometry (LC-MS/MS) was deve[r] ... See full document

1

Determination of dextromethorphan in rabbit plasma by LC-MS/MS and its application to pharmacokinetic study

Determination of dextromethorphan in rabbit plasma by LC-MS/MS and its application to pharmacokinetic study

... A highly sensitive liquid chromatographic tandem mass spectrometric (LC-MS/MS) method for determination of dextromethorphan in rabbit plasma using triazolam as the internal standard (IS)[r] ... See full document

1

Determination of free amino acids in plants by liquid chromatography coupled to tandem mass spectrometry (LC MS/MS)

Determination of free amino acids in plants by liquid chromatography coupled to tandem mass spectrometry (LC MS/MS)

... content in plant samples (leaves and stalks), collected from pot experiments, they were placed in a mortar and ground with a pestle using liquid ...followed by 15 min sonification in ... See full document

17

Determination of ketamine in rabbit plasma by gradient elution liquid chromatography/electrospray mass spectrometry

Determination of ketamine in rabbit plasma by gradient elution liquid chromatography/electrospray mass spectrometry

... A sensitive and simple liquid chromatography/electrospray mass spectrometry (LC-ESI-MS) method for determination of ketamine in rabbit plasma using one-step protein precipitation was dev[r] ... See full document

1

Determination of tolbutamide and hydroxytolbutamide by LC–MS/MS in rat and its application to assessment of CYP2C9 activity

Determination of tolbutamide and hydroxytolbutamide by LC–MS/MS in rat and its application to assessment of CYP2C9 activity

... A sensitive and selective liquid chromatography–tandem mass spectrometry method (LC–MS/MS) for the determination of tolbutamide (TB) and its metabolite hydroxytolbutamide (HTB) in rat pl[r] ... See full document

1

Determination of bupropion hydrochloride in rat plasma by LC-MS/MS and Its application to pharmacokinetic study

Determination of bupropion hydrochloride in rat plasma by LC-MS/MS and Its application to pharmacokinetic study

... A selective and sensitive liquid chromatography-tandem mass spectrometry method was de- veloped and validated for quantitation of bupropion hydrochloride in rat plasma using triazolam as[r] ... See full document

1

Simultaneous determination of four cytochrome p450 probe drugs in rat plasma by a simple liquid chromatography–mass spectrometry method

Simultaneous determination of four cytochrome p450 probe drugs in rat plasma by a simple liquid chromatography–mass spectrometry method

... simple liquid chromatography- mass spectrometry (LC-MS) method was de- veloped and validated for determination of four cytochrome P450 probe drugs (phenacetin (CYP1A2), ... See full document

1

Gradient elution LC-ESI-MS determination of tramadol in rat plasma

Gradient elution LC-ESI-MS determination of tramadol in rat plasma

... A sensitive and simple liquid chromatography/electrospray mass spectrometry (LC-ESI-MS) method for determination of tramadol in rat plasma using one-step protein precipitation was develo[r] ... See full document

1

Determination of tolbutamide in rabbit plasma by LC-MS/MS and its application to pharmacokinetic study

Determination of tolbutamide in rabbit plasma by LC-MS/MS and its application to pharmacokinetic study

... A sensitive and selective liquid chromatography–tandem mass spectrometry method (LC–MS/MS) for the determination of tolbutamide in rabbit plasma was developed and validated over the conc[r] ... See full document

1

Determination of ibudilast in rabbit plasma by liquid chromatography-mass spectrometry and its application

Determination of ibudilast in rabbit plasma by liquid chromatography-mass spectrometry and its application

... Detection involved positive ion mode electrospray ion- ization (ESI), and selective ion monitoring (SIM) mode was used for quantification of target fragment ions m/z 230.7 for ibudilast [r] ... See full document

1

Determination of dezocine in rabbit plasma by liquid chromatography-mass spectrometry and its application

Determination of dezocine in rabbit plasma by liquid chromatography-mass spectrometry and its application

... Detection involved positive ion mode electrospray ioniza- tion (ESI), and selective ion monitoring ( SIM ) mode was used for quantification of target fragment ions m/z 245.8 for dezocine[r] ... See full document

1

Robustness testing in the determination of seven drugs in animal muscle by liquid chromatography–tandem mass spectrometry

Robustness testing in the determination of seven drugs in animal muscle by liquid chromatography–tandem mass spectrometry

... identification of the potentially influential factors and the definition of their variation ranges and of the responses to be ...as in the Youden test [13], is the most frequently used ... See full document

22

Quantification of torsemide in rabbit plasma by liquid chromatography/electrospray mass spectrometry and its application

Quantification of torsemide in rabbit plasma by liquid chromatography/electrospray mass spectrometry and its application

... A sensitive and simple liquid chromatography/electrospray mass spectrometry (LC-ESI-MS) method for determination of torsemide in rabbit plasma using one-step protein precipitation was de[r] ... See full document

1

Determination of tetramethylpyrazine in rat plasma by liquid chromatography/electrospray mass spectrometry

Determination of tetramethylpyrazine in rat plasma by liquid chromatography/electrospray mass spectrometry

... Electrospray ionization (ESI) source was applied and operated in positive ion mode; selected ion monitoring (SIM) mode was used to quantify tetramethylpyrazine using target fragment ions[r] ... See full document

1

Determination of esomeprazole in rabbit plasma by liquid chromatography-mass spectrometry and its application to a pharmacokinetic study

Determination of esomeprazole in rabbit plasma by liquid chromatography-mass spectrometry and its application to a pharmacokinetic study

... Detection involved positive ion mode electrospray ion- ization (ESI), and selective ion monitoring (SIM) mode was used for quantification of target fragment ions m/z 198 for esomeprazol[r] ... See full document

1

Determination of diphenhydramine hydrochloride in rabbit plasma by LC-MS/MS and its application to a pharmacokinetic study

Determination of diphenhydramine hydrochloride in rabbit plasma by LC-MS/MS and its application to a pharmacokinetic study

... A sensitive and selective liquid chromatography tandem mass spectrometry (LC–MS/MS) method for determination of diphenhydramine hydrochloride in rabbit plasma was developed and validat- [r] ... See full document

1

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